Search Results - "BECKER, RÜDIGER"

Journal Article

Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels

by Schmidt, Constanze Wiedmann, Felix Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Naunyn-Schmiedeberg's archives of pharmacology (01.10.2012)

“...Dronedarone is currently used for the treatment of paroxysmal and persistent atrial fibrillation (AF). Pharmacological inhibition of cardiac two-pore-domain...”

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Journal Article

Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model

by BIKOU, Olympia THOMAS, Dierk BAUER, Alexander TRAPPE, Kerstin LUGENBIEL, Patrick KELEMEN, Kamilla KOCH, Martin SOUCEK, Radim VOSS, Frederik BECKER, Rudiger KATUS, Hugo A Published in Cardiovascular research (2011)

“...Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, and effective treatment of AF still remains an unmet medical need. AF is associated...”

Journal Article

Identification and functional characterization of zebrafish K(2P)10.1 (TREK2) two-pore-domain K(+) channels

by Gierten, Jakob Hassel, David Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Biochimica et biophysica acta (01.01.2012)

“...Two-pore-domain potassium (K(2P)) channels mediate K(+) background currents that stabilize the resting membrane potential and contribute to repolarization of...”

Journal Article

PKC‐dependent activation of human K2P18.1 K+ channels

by Rahm, Ann‐Kathrin Gierten, Jakob Kisselbach, Jana Staudacher, Ingo Staudacher, Kathrin Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in British journal of pharmacology (01.05.2012)

“...BACKGROUND AND PURPOSE Two‐pore‐domain K+ channels (K2P) mediate K+ background currents that modulate the membrane potential of excitable cells. K2P18.1...”

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Journal Article

Anxiety Disorders in Patients with Implantable Cardioverter Defibrillators: Frequency, Course, Predictors, and Patients’ Requests for Treatment

by LANG, SASKIA BECKER, RÜDIGER WILKE, STEFANIE HARTMANN, MECHTHILD HERZOG, WOLFGANG LÖWE, BERND Published in Pacing and clinical electrophysiology (01.01.2014)

“...Objectives To determine (1) the frequency and course of anxiety disorders in patients with implantable cardioverter defibrillators (ICDs), (2) the predictors...”

Journal Article

Successful acute and long-term management of electrical storm in Brugada syndrome using orciprenaline and quinine/quinidine

by Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Clinical research in cardiology (01.07.2010)

Journal Article

Prophylactic implantation of cardioverter-defibrillator in patients with severe cardiac amyloidosis and high risk for sudden cardiac death

by Kristen, Arnt V., MD Dengler, Thomas J., MD Hegenbart, Ute, MD Schonland, Stefan O., MD Goldschmidt, Hartmut, MD Sack, Falk-Udo, MD Voss, Frederik, MD Becker, Rüdiger, MD Katus, Hugo A., MD Bauer, Alexander, MD Published in Heart rhythm (2008)

“...Background Cardiac light-chain amyloidosis carries a high risk for death predominantly from progressive cardiomyopathy or sudden death (SCD). Independent risk...”

Journal Article

Implantable Defibrillators With Enhanced Detection Algorithms: Detection Performance and Safety Results from the PainFree SST Study

by WOLLMANN, CHRISTIAN G LAWO, THOMAS KÜHLKAMP, VOLKER BECKER, RÜDIGER GARUTTI, CLAUDIO JACKSON, TROY BROWN, MARK L MAYR, HARALD Published in Pacing and clinical electrophysiology (01.09.2014)

“...Background Implantable defibrillators (ICD) are highly effective in reducing arrhythmia‐related mortality. ICD shock therapy has been shown to increase...”

Journal Article

Biophysical properties of mutant KCNQ1 S277L channels linked to hereditary long QT syndrome with phenotypic variability

by Aidery, Parwez Kisselbach, Jana Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Biochimica et biophysica acta. Molecular basis of disease (01.04.2011)

“...Hereditary long QT syndrome (LQTS) is associated with ventricular torsade de pointes tachyarrhythmias and sudden cardiac death. Mutations in a cardiac...”

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Journal Article

Impaired ion channel function related to a common KCNQ1 mutation — Implications for risk stratification in long QT syndrome 1

by Aidery, Parwez Kisselbach, Jana Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Gene (10.12.2012)

“...Long QT syndrome (LQTS) 1 is the most common type of inherited LQTS and is linked to mutations in the KCNQ1 gene. We identified a KCNQ1 missense mutation,...”

Journal Article

Identification and functional characterization of zebrafish K2P10.1 (TREK2) two-pore-domain K+ channels

by Gierten, Jakob Hassel, David Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Biochimica et biophysica acta. Biomembranes (01.01.2012)

“...Two-pore-domain potassium (K2P) channels mediate K+ background currents that stabilize the resting membrane potential and contribute to repolarization of...”

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Journal Article

Genetic suppression of atrial fibrillation using a dominant-negative ether-a-go-go–related gene mutant

by Soucek, Radim, MD Thomas, Dierk, MD Kelemen, Kamilla, MD Bikou, Olympia, MD Seyler, Claudia, PhD Voss, Frederik, MD Becker, Rüdiger, MD Koenen, Michael, PhD Katus, Hugo A., MD Bauer, Alexander, MD Published in Heart rhythm (2012)

“...Background Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Gene therapy–dependent modulation of atrial electrophysiology may provide...”

Journal Article

Initial experience with robotic navigation for catheter ablation of paroxysmal and persistent atrial fibrillation

by Thomas, Dierk, MD Scholz, Eberhard P., MD Schweizer, Patrick A., MD Katus, Hugo A., MD Becker, Rüdiger, MD Published in Journal of electrocardiology (2012)

“...Abstract Background and Purpose Remote robotic navigation (RRN) technology has been developed to facilitate catheter ablation of symptomatic atrial...”

Journal Article

Alternative splicing determines mRNA translation initiation and function of human K2P10.1 K+ channels

by Staudacher, Kathrin Baldea, Ioana Kisselbach, Jana Staudacher, Ingo Rahm, Ann‐Kathrin Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in The Journal of physiology (01.08.2011)

“...Non‐technical summary The resting membrane potential of excitable cells such as neurones and cardiac myocytes depends on the distribution of potassium ions...”

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Journal Article

Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation

by Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Drug design, development and therapy (06.01.2011)

“...Atrial fibrillation (AF) is the most common sustained arrhythmia. Management of AF includes rate control, rhythm control if necessary, prevention of...”

Journal Article

The Novel cAMP-Insensitive HCN4-695X Mutation is Associated with Marked Sinus Bradycardia but Regular Autonomic Rate Control

by Schweizer, Patrick Duhme, Nana Thomas, Dierk Becker, Rüdiger Zehelein, Jörg Draguhn, Andreas Bruehl, Claus Katus, Hugo A Koenen, Michael Published in Biophysical journal (2011)

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Journal Article

Efficacy, High Procedural Safety And Rapid Optimization Of Cryoballoon Atrial Fibrillation Ablation In The Hands Of A New Operator

by Scholz, Eberhard Lugenbiel, Patrick Schweizer, Patrick A Xynogalos, Panagiotis Seyler, Claudia Zitron, Edgar Becker, Rüdiger Katus, Hugo A Thomas, Dierk Published in Journal of atrial fibrillation (01.02.2016)

“...Cryoballoon (CB) ablation is successful in eliminating atrial fibrillation (AF). The purpose of this study was to assess procedural efficacy and safety of CB...”

Journal Article

Effects of [beta]-blocker therapy on electrocardiographic and echocardiographic characteristics of left ventricular noncompaction

by Li, Jin Franke, Jennifer Pribe-Wolferts, Regina Meder, Benjamin Ehlermann, Philipp Mereles, Derliz Andre, Florian Abdelrazek, Mohamed Assem Merten, Constanze Schweizer, Patrick A Becker, Rudiger Katus, Hugo A Thomas, Dierk Published in Clinical research in cardiology (01.03.2015)

Journal Article

CATHETER ABLATION OF ATRIAL FLUTTER: ACUTE AND LONG-TERM RESULTS

by Luciani, Etienne Nagy, Marliese Brachmann, Johannes Kuck, Karl-Heinz Andresen, Dietrich Willems, Stephan Hoffmann, Ellen Schumacher, Burghard Lewalter, Thorsten Spitzer, Stefan Tebbenjohanns, Jürgen Becker, Rüdiger Senges, Jochen Gonska, Bernd-Dieter Published in Journal of the American College of Cardiology (2011)

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Journal Article

HERG K+ channel-dependent apoptosis and cell cycle arrest in human glioblastoma cells

by Staudacher, Ingo Jehle, Julian Staudacher, Kathrin Pledl, Hans-Werner Lemke, Dieter Schweizer, Patrick A Becker, Rüdiger Katus, Hugo A Thomas, Dierk
edited by Bishopric, Nanette H
Published in PloS one (2014-00-00)

“...Glioblastoma (GB) is associated with poor patient survival owing to uncontrolled tumor proliferation and resistance to apoptosis. Human ether-a-go-go-related...”

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