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1by Brodowicz, Thomas Liegl-Atzwager, Bernadette Tresch, Emmanuelle Taieb, Sophie Kramar, Andrew Gruenwald, Viktor Vanseymortier, Marie Clisant, Stéphanie Blay, Jean-Yves Le Cesne, Axel Penel, Nicolas Published in BMC cancer (14.03.2015)“...Angiogenesis, among other signaling pathways, plays a key-role in sarcoma biology. Regorafenib (RE) has recently been shown to be effective in imatinib and...”
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2by Eroukhmanoff, Juliette Castinetti, Frederic Penel, Nicolas Salas, Sebastien Published in BMC cancer (24.08.2016)“...While hypothyroidism has frequently been reported with the use of TKIs, the thyroid-stimulating hormone (TSH) suppressing effect of TKIs is rare, except for...”
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3by Grellety, Thomas Cousin, Sophie Letinier, Louis Bosco-Lévy, Pauline Hoppe, Stéphanie Joly, Damien Penel, Nicolas Mathoulin-Pelissier, Simone Italiano, Antoine Published in BMC cancer (04.10.2016)“...Optimizing patient selection is a necessary step to design better clinical trials. 'Life expectancy' is a frequent inclusion criterion in phase II trial...”
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4by Genin, Marie Clement, Francois Fattaccioli, Antoine Raes, Martine Michiels, Carine Published in BMC cancer (08.08.2015)“...Tumor associated macrophages (TAMs) are present in high density in solid tumors. TAMs share many characteristics with alternatively activated macrophages, also...”
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5“...Exosomes are nanovesicles secreted by tumour cells which have roles in paracrine signalling during tumour progression, including tumour-stromal interactions,...”
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6by Lu, Kai-hua Li, Wei Liu, Xiang-hua Sun, Ming Zhang, Mei-ling Wu, Wei-qin Xie, Wei-ping Hou, Ya-yi Published in BMC cancer (07.10.2013)“...Long non-coding RNAs play an important role in tumorigenesis, hence, identification of cancer-associated lncRNAs and investigation of their biological...”
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7by Engstrand, Jennie Nilsson, Henrik Strömberg, Cecilia Jonas, Eduard Freedman, Jacob Published in BMC cancer (15.01.2018)“...Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with liver metastases developing in 25-30% of those affected. Previous data suggest a...”
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8by Liu, Xiang-hua Liu, Zhi-li Sun, Ming Liu, Jing Wang, Zhao-xia De, Wei Published in BMC cancer (08.10.2013)“...The identification of cancer-associated long non-coding RNAs and the investigation of their molecular and biological functions are important for understanding...”
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9by Sekulic, Aleksandar Migden, Michael R Basset-Seguin, Nicole Garbe, Claus Gesierich, Anja Lao, Christopher D Miller, Chris Mortier, Laurent Murrell, Dedee F Hamid, Omid Quevedo, Jorge F Hou, Jeannie McKenna, Edward Dimier, Natalie Williams, Sarah Schadendorf, Dirk Hauschild, Axel Published in BMC cancer (16.05.2017)“...In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration-approved Hedgehog pathway inhibitor, showed objective...”
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10by Sun, Ming Jin, Fei-yan Xia, Rui Kong, Rong Li, Jin-hai Xu, Tong-peng Liu, Yan-wen Zhang, Er-bao Liu, Xiang-hua De, Wei Published in BMC cancer (06.05.2014)“...Gastric cancer is the second leading cause of cancer death and remains a major clinical challenge due to poor prognosis and limited treatment options. Long...”
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11“...We recently published PROGgene, a tool that can be used to study prognostic implications of genes in various cancers. The first version of the tool had several...”
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12“...Surgical resection remains the primary treatment for gastrointestinal (GI) malignancy including early-stage cancer. Omega-3 polyunsaturated fatty acids (n-3...”
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13by Gorges, Tobias M Tinhofer, Ingeborg Drosch, Michael Röse, Lars Zollner, Thomas M Krahn, Thomas von Ahsen, Oliver Published in BMC cancer (16.05.2012)“...Circulating tumour cells (CTCs) have shown prognostic relevance in metastatic breast, prostate, colon and pancreatic cancer. For further development of CTCs as...”
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14by Medrek, Catharina Pontén, Fredrik Jirström, Karin Leandersson, Karin Published in BMC cancer (23.07.2012)“...Tumor associated macrophages (TAMs) are alternatively activated macrophages that enhance tumor progression by promoting tumor cell invasion, migration and...”
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15by Lee, Suee Oh, Sung Yong Kim, Sung Hyun Lee, Ji Hyun Kim, Min Chan Kim, Ki Han Kim, Hyo-Jin Published in BMC cancer (22.07.2013)“...Several inflammatory response materials could be used for prediction of prognosis of cancer patients. The neutrophil lymphocyte ratio (NLR), and the platelet...”
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16by Smith, J Joshua Chow, Oliver S Gollub, Marc J Nash, Garrett M Temple, Larissa K Weiser, Martin R Guillem, José G Paty, Philip B Avila, Karin Garcia-Aguilar, Julio Published in BMC cancer (23.10.2015)“...Treatment of patients with non-metastatic, locally advanced rectal cancer (LARC) includes pre-operative chemoradiation, total mesorectal excision (TME) and...”
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17by Mrozik, Krzysztof Marek Blaschuk, Orest William Cheong, Chee Man Zannettino, Andrew Christopher William Vandyke, Kate Published in BMC cancer (01.10.2018)“...In many types of solid tumours, the aberrant expression of the cell adhesion molecule N-cadherin is a hallmark of epithelial-to-mesenchymal transition,...”
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18by Webb, Anderson H Gao, Bradley T Goldsmith, Zachary K Irvine, Andrew S Saleh, Nabil Lee, Ryan P Lendermon, Justin B Bheemreddy, Rajini Zhang, Qiuhua Brennan, Rachel C Johnson, Dianna Steinle, Jena J Wilson, Matthew W Morales-Tirado, Vanessa M Published in BMC cancer (20.06.2017)“...Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed...”
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19by Nielsen, Torsten Wallden, Brett Schaper, Carl Ferree, Sean Liu, Shuzhen Gao, Dongxia Barry, Garrett Dowidar, Naeem Maysuria, Malini Storhoff, James Published in BMC cancer (13.03.2014)“...NanoString's Prosigna™ Breast Cancer Prognostic Gene Signature Assay is based on the PAM50 gene expression signature. The test outputs a risk of recurrence...”
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20by Endzeliņš, Edgars Berger, Andreas Melne, Vita Bajo-Santos, Cristina Soboļevska, Kristīne Ābols, Artūrs Rodriguez, Marta Šantare, Daiga Rudņickiha, Anastasija Lietuvietis, Vilnis Llorente, Alicia Linē, Aija Published in BMC cancer (09.11.2017)“...Circulating cell-free miRNAs have emerged as promising minimally-invasive biomarkers for early detection, prognosis and monitoring of cancer. They can exist in...”