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  • Your search results: "BMC cancer"
Showing 1 - 20 results of 14,262 for search '"BMC cancer"', query time: 2.19s Narrow search
  • 1
    Cover Image Journal Article
    Study protocol of REGOSARC trial: activity and safety of regorafenib in advanced soft tissue sarcoma: a multinational, randomized, placebo-controlled, phase II trial
    by Brodowicz, Thomas   Liegl-Atzwager, Bernadette   Tresch, Emmanuelle   Taieb, Sophie   Kramar, Andrew   Gruenwald, Viktor   Vanseymortier, Marie   Clisant, Stéphanie   Blay, Jean-Yves   Le Cesne, Axel   Penel, Nicolas Published in BMC cancer (14.03.2015)
    “...Angiogenesis, among other signaling pathways, plays a key-role in sarcoma biology. Regorafenib (RE) has recently been shown to be effective in imatinib and...”
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  • 2
    Cover Image Journal Article
    Auto-immune thyroid dysfunction induced by tyrosine kinase inhibitors in a patient with recurrent chordoma
    by Eroukhmanoff, Juliette   Castinetti, Frederic   Penel, Nicolas   Salas, Sebastien Published in BMC cancer (24.08.2016)
    “...While hypothyroidism has frequently been reported with the use of TKIs, the thyroid-stimulating hormone (TSH) suppressing effect of TKIs is rare, except for...”
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  • 3
    Cover Image Journal Article
    PRognostic factor of Early Death In phase II Trials or the end of 'sufficient life expectancy' as an inclusion criterion? (PREDIT model)
    by Grellety, Thomas   Cousin, Sophie   Letinier, Louis   Bosco-Lévy, Pauline   Hoppe, Stéphanie   Joly, Damien   Penel, Nicolas   Mathoulin-Pelissier, Simone   Italiano, Antoine Published in BMC cancer (04.10.2016)
    “...Optimizing patient selection is a necessary step to design better clinical trials. 'Life expectancy' is a frequent inclusion criterion in phase II trial...”
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  • 4
    Cover Image Journal Article
    M1 and M2 macrophages derived from THP-1 cells differentially modulate the response of cancer cells to etoposide
    by Genin, Marie   Clement, Francois   Fattaccioli, Antoine   Raes, Martine   Michiels, Carine Published in BMC cancer (08.08.2015)
    “...Tumor associated macrophages (TAMs) are present in high density in solid tumors. TAMs share many characteristics with alternatively activated macrophages, also...”
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  • 5
    Cover Image Journal Article
    Hypoxic enhancement of exosome release by breast cancer cells
    by King, Hamish W   Michael, Michael Z   Gleadle, Jonathan M Published in BMC cancer (24.09.2012)
    “...Exosomes are nanovesicles secreted by tumour cells which have roles in paracrine signalling during tumour progression, including tumour-stromal interactions,...”
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  • 6
    Cover Image Journal Article
    Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression
    by Lu, Kai-hua   Li, Wei   Liu, Xiang-hua   Sun, Ming   Zhang, Mei-ling   Wu, Wei-qin   Xie, Wei-ping   Hou, Ya-yi Published in BMC cancer (07.10.2013)
    “...Long non-coding RNAs play an important role in tumorigenesis, hence, identification of cancer-associated lncRNAs and investigation of their biological...”
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  • 7
    Cover Image Journal Article
    Colorectal cancer liver metastases—A population‐based study on incidence, management and survival
    by Engstrand, Jennie   Nilsson, Henrik   Strömberg, Cecilia   Jonas, Eduard   Freedman, Jacob Published in BMC cancer (15.01.2018)
    “...Colorectal cancer (CRC) is a leading cause of cancer-associated deaths with liver metastases developing in 25-30% of those affected. Previous data suggest a...”
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  • 8
    Cover Image Journal Article
    The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer
    by Liu, Xiang-hua   Liu, Zhi-li   Sun, Ming   Liu, Jing   Wang, Zhao-xia   De, Wei Published in BMC cancer (08.10.2013)
    “...The identification of cancer-associated long non-coding RNAs and the investigation of their molecular and biological functions are important for understanding...”
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  • 9
    Cover Image Journal Article
    Long‐term safety and efficacy of vismodegib in patients with advanced basal cell carcinoma: Final update of the pivotal ERIVANCE BCC study
    by Sekulic, Aleksandar   Migden, Michael R   Basset-Seguin, Nicole   Garbe, Claus   Gesierich, Anja   Lao, Christopher D   Miller, Chris   Mortier, Laurent   Murrell, Dedee F   Hamid, Omid   Quevedo, Jorge F   Hou, Jeannie   McKenna, Edward   Dimier, Natalie   Williams, Sarah   Schadendorf, Dirk   Hauschild, Axel Published in BMC cancer (16.05.2017)
    “...In the primary analysis of the ERIVANCE BCC trial, vismodegib, the first US Food and Drug Administration-approved Hedgehog pathway inhibitor, showed objective...”
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  • 10
    Cover Image Journal Article
    Decreased expression of long noncoding RNA GAS5 indicates a poor prognosis and promotes cell proliferation in gastric cancer
    by Sun, Ming   Jin, Fei-yan   Xia, Rui   Kong, Rong   Li, Jin-hai   Xu, Tong-peng   Liu, Yan-wen   Zhang, Er-bao   Liu, Xiang-hua   De, Wei Published in BMC cancer (06.05.2014)
    “...Gastric cancer is the second leading cause of cancer death and remains a major clinical challenge due to poor prognosis and limited treatment options. Long...”
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  • 11
    Cover Image Journal Article
    PROGgeneV2: enhancements on the existing database
    by Goswami, Chirayu Pankaj   Nakshatri, Harikrishna Published in BMC cancer (17.12.2014)
    “...We recently published PROGgene, a tool that can be used to study prognostic implications of genes in various cancers. The first version of the tool had several...”
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  • 12
    Cover Image Journal Article
    Effects of omega-3 fatty acids on patients undergoing surgery for gastrointestinal malignancy: a systematic review and meta-analysis
    by Yu, Jing   Liu, Lian   Zhang, Yue   Wei, Jia   Yang, Fan Published in BMC cancer (14.04.2017)
    “...Surgical resection remains the primary treatment for gastrointestinal (GI) malignancy including early-stage cancer. Omega-3 polyunsaturated fatty acids (n-3...”
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  • 13
    Cover Image Journal Article
    Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition
    by Gorges, Tobias M   Tinhofer, Ingeborg   Drosch, Michael   Röse, Lars   Zollner, Thomas M   Krahn, Thomas   von Ahsen, Oliver Published in BMC cancer (16.05.2012)
    “...Circulating tumour cells (CTCs) have shown prognostic relevance in metastatic breast, prostate, colon and pancreatic cancer. For further development of CTCs as...”
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  • 14
    Cover Image Journal Article
    The presence of tumor associated macrophages in tumor stroma as a prognostic marker for breast cancer patients
    by Medrek, Catharina   Pontén, Fredrik   Jirström, Karin   Leandersson, Karin Published in BMC cancer (23.07.2012)
    “...Tumor associated macrophages (TAMs) are alternatively activated macrophages that enhance tumor progression by promoting tumor cell invasion, migration and...”
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  • 15
    Cover Image Journal Article
    Prognostic significance of neutrophil lymphocyte ratio and platelet lymphocyte ratio in advanced gastric cancer patients treated with FOLFOX chemotherapy
    by Lee, Suee   Oh, Sung Yong   Kim, Sung Hyun   Lee, Ji Hyun   Kim, Min Chan   Kim, Ki Han   Kim, Hyo-Jin Published in BMC cancer (22.07.2013)
    “...Several inflammatory response materials could be used for prediction of prognosis of cancer patients. The neutrophil lymphocyte ratio (NLR), and the platelet...”
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  • 16
    Cover Image Journal Article
    Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated...
    by Smith, J Joshua   Chow, Oliver S   Gollub, Marc J   Nash, Garrett M   Temple, Larissa K   Weiser, Martin R   Guillem, José G   Paty, Philip B   Avila, Karin   Garcia-Aguilar, Julio Published in BMC cancer (23.10.2015)
    “...Treatment of patients with non-metastatic, locally advanced rectal cancer (LARC) includes pre-operative chemoradiation, total mesorectal excision (TME) and...”
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  • 17
    Cover Image Journal Article
    N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer
    by Mrozik, Krzysztof Marek   Blaschuk, Orest William   Cheong, Chee Man   Zannettino, Andrew Christopher William   Vandyke, Kate Published in BMC cancer (01.10.2018)
    “...In many types of solid tumours, the aberrant expression of the cell adhesion molecule N-cadherin is a hallmark of epithelial-to-mesenchymal transition,...”
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  • 18
    Cover Image Journal Article
    Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma
    by Webb, Anderson H   Gao, Bradley T   Goldsmith, Zachary K   Irvine, Andrew S   Saleh, Nabil   Lee, Ryan P   Lendermon, Justin B   Bheemreddy, Rajini   Zhang, Qiuhua   Brennan, Rachel C   Johnson, Dianna   Steinle, Jena J   Wilson, Matthew W   Morales-Tirado, Vanessa M Published in BMC cancer (20.06.2017)
    “...Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed...”
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  • 19
    Cover Image Journal Article
    Analytical validation of the PAM50-based Prosigna Breast Cancer Prognostic Gene Signature Assay and nCounter Analysis System using formalin-fixed paraffin-embedded breast tumor spe...
    by Nielsen, Torsten   Wallden, Brett   Schaper, Carl   Ferree, Sean   Liu, Shuzhen   Gao, Dongxia   Barry, Garrett   Dowidar, Naeem   Maysuria, Malini   Storhoff, James Published in BMC cancer (13.03.2014)
    “...NanoString's Prosigna™ Breast Cancer Prognostic Gene Signature Assay is based on the PAM50 gene expression signature. The test outputs a risk of recurrence...”
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  • 20
    Cover Image Journal Article
    Detection of circulating miRNAs: comparative analysis of extracellular vesicle-incorporated miRNAs and cell-free miRNAs in whole plasma of prostate cancer patients
    by Endzeliņš, Edgars   Berger, Andreas   Melne, Vita   Bajo-Santos, Cristina   Soboļevska, Kristīne   Ābols, Artūrs   Rodriguez, Marta   Šantare, Daiga   Rudņickiha, Anastasija   Lietuvietis, Vilnis   Llorente, Alicia   Linē, Aija Published in BMC cancer (09.11.2017)
    “...Circulating cell-free miRNAs have emerged as promising minimally-invasive biomarkers for early detection, prognosis and monitoring of cancer. They can exist in...”
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