“...The genome of the protozoan parasite Plasmodium falciparum, the causative agent of the most lethal type of human malaria, contains a single gene annotated as...”

“...CA II protein fold, Zn(II) ion, and its coordination by three histidine residues. Carbonic anhydrases (CAs, EC 4.2.1.1) are widespread enzymes in all...”

“...[Display omitted] Resistance to available antibiotics in pathogenic bacteria is currently a global challenge since the number of strains that are resistant to...”

“...[Display omitted] Proteolysis targeting chimeras (PROTACs) are heterobifunctional compounds with molecular weights and other properties that lie outside the...”

“...Repeated guanine tracts in human and other genomes can form higher-order four stranded structures, termed quadruplexes. In the human genome they have...”

“...[Display omitted] 20-(S)-Camptothecin (CPT) is a natural alkaloid extracted from the bark of Camptotheca acuminata (Chinese happy tree). It acts as a DNA...”

“...[Display omitted] •First small molecule degraders for zinc-dependent HDACs.•HDAC6 selective degraders.•Selectively remove HDAC6 by the...”