Search Results - "Carpentier, Andre C"

Journal Article

Image-derived input function in dynamic human PET/CT: methodology and validation with 11C-acetate and 18F-fluorothioheptadecanoic acid in muscle and 18F-fluorodeoxyglucose in brain

by Croteau, Etienne Lavallée, Eric Labbe, Sébastien M Hubert, Laurent Pifferi, Fabien Rousseau, Jacques A Cunnane, Stephen C Carpentier, André C Lecomte, Roger Bénard, François Published in European journal of nuclear medicine and molecular imaging (01.08.2010)

“...Despite current advances in PET/CT systems, blood sampling still remains the standard method to obtain the radiotracer input function for tracer kinetic...”

Journal Article

Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans

by Ouellet, Véronique Labbé, Sébastien M Blondin, Denis P Phoenix, Serge Guérin, Brigitte Haman, François Turcotte, Eric E Richard, Denis Carpentier, André C Published in The Journal of clinical investigation (01.02.2012)

“...Brown adipose tissue (BAT) is vital for proper thermogenesis during cold exposure in rodents, but until recently its presence in adult humans and its...”

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Journal Article

Outdoor Temperature, Age, Sex, Body Mass Index, and Diabetic Status Determine the Prevalence, Mass, and Glucose-Uptake Activity of 18F-FDG-Detected BAT in Humans

by Ouellet, Veronique Routhier-Labadie, Annick Bellemare, William Lakhal-Chaieb, Lajmi Turcotte, Eric Carpentier, André C Richard, Denis Published in The journal of clinical endocrinology and metabolism (01.01.2011)

“...Context: In humans, the prevalence, mass, and glucose-uptake activity of 18F-fluorodeoxyglucose (18F-FDG)-detected brown adipose tissue (BAT), which are...”

Journal Article

Lipid-induced pancreatic β-cell dysfunction: focus on in vivo studies

by Adria Giacca Changting Xiao Andrei I. Oprescu Andre C. Carpentier Gary F. Lewis Published in American Journal of Physiology - Endocrinology And Metabolism (01.02.2011)

“...The phenomenon of lipid-induced pancreatic β-cell dysfunction (“lipotoxicity”) has been very well documented in numerous in vitro experimental systems and has...”

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Journal Article

Contributions of white and brown adipose tissues and skeletal muscles to acute cold‐induced metabolic responses in healthy men

by Blondin, Denis P Labbé, Sébastien M Phoenix, Serge Guérin, Brigitte Turcotte, Éric E Richard, Denis Carpentier, André C Haman, François Published in The Journal of physiology (01.02.2015)

“...Key points Both brown adipose tissue (BAT) and skeletal muscle activation contribute to the metabolic response of acute cold exposure in healthy men even under...”

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Journal Article

Branched-chain Amino Acid Catabolism by Brown Adipose Tissue

by Carpentier, André C Published in Endocrinology (Philadelphia) (01.07.2020)

Journal Article

Dietary fatty acid metabolism of brown adipose tissue in cold-acclimated men

by Blondin, Denis P Tingelstad, Hans C Noll, Christophe Frisch, Frédérique Phoenix, Serge Guérin, Brigitte Turcotte, Éric E Richard, Denis Haman, François Carpentier, André C Published in Nature communications (30.01.2017)

“...In rodents, brown adipose tissue (BAT) plays an important role in producing heat to defend against the cold and can metabolize large amounts of dietary fatty...”

Journal Article

Increased Brown Adipose Tissue Oxidative Capacity in Cold-Acclimated Humans

by Blondin, Denis P Labbé, Sébastien M Tingelstad, Hans C Noll, Christophe Kunach, Margaret Phoenix, Serge Guérin, Brigitte Turcotte, Éric E Carpentier, André C Richard, Denis Haman, François Published in The journal of clinical endocrinology and metabolism (01.03.2014)

“...Context: Recent studies examining brown adipose tissue (BAT) metabolism in adult humans have provided convincing evidence of its thermogenic potential and role...”

Journal Article

Brown adipose tissue energy metabolism in humans

by Carpentier, André C Blondin, Denis P Virtanen, Kirsi A Richard, Denis Haman, François Turcotte, Éric E Published in Frontiers in endocrinology (Lausanne) (2018-00-00)

“...The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily using positron emission tomography coupled to computed tomography...”

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Journal Article

Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications

by Barrière, David André Noll, Christophe Roussy, Geneviève Lizotte, Farah Kessai, Anissa Kirby, Karyn Belleville, Karine Beaudet, Nicolas Longpré, Jean-Michel Carpentier, André C Geraldes, Pedro Sarret, Philippe Published in Scientific reports (11.01.2018)

“...The epidemic of type 2 diabetes mellitus (T2DM) is fueled by added fructose consumption. Here, we thus combined high-fat/high-fructose diet, with multiple...”

Journal Article

Limited recovery of β-cell function after gastric bypass despite clinical diabetes remission

by DUTIA, Roxanne BRAKONIECKI, Katrina BUNKER, Phoebe PAULTRE, Furcy HOMEL, Peter CARPENTIER, André C MCGINTY, James LAFERRERE, Blandine Published in Diabetes (New York, N.Y.) (2014)

“...The mechanisms responsible for the remarkable remission of type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) are still puzzling. To elucidate the role of...”

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Journal Article

Four‐week cold acclimation in adult humans shifts uncoupling thermogenesis from skeletal muscles to brown adipose tissue

by Blondin, Denis P Daoud, Amani Taylor, Taryn Tingelstad, Hans C Bézaire, Véronic Richard, Denis Carpentier, André C Taylor, Albert W Harper, Mary‐Ellen Aguer, Céline Haman, François Published in The Journal of physiology (15.03.2017)

“...Key points Muscle‐derived thermogenesis during acute cold exposure in humans consists of a combination of cold‐induced increases in skeletal muscle proton leak...”

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Journal Article

Selective impairment of glucose but not fatty acid or oxidative metabolism in brown adipose tissue of subjects with type 2 diabetes

by Blondin, Denis P Labbé, Sébastien M Noll, Christophe Kunach, Margaret Phoenix, Serge Guérin, Brigitte Turcotte, Éric E Haman, François Richard, Denis Carpentier, André C Published in Diabetes (New York, N.Y.) (01.07.2015)

“...Spontaneous glucose uptake by brown adipose tissue (BAT) is lower in overweight or obese individuals and in diabetes. However, BAT metabolism has not been...”

Journal Article

2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult

by Anderson, Todd J., MD Grégoire, Jean, MD Hegele, Robert A., MD Couture, Patrick, MD, PhD Mancini, G.B. John, MD McPherson, Ruth, MD, PhD Francis, Gordon A., MD Poirier, Paul, MD, PhD Lau, David C., MD, PhD Grover, Steven, MD Genest, Jacques, MD Carpentier, André C., MD Dufour, Robert, MD Gupta, Milan, MD Ward, Richard, MD Leiter, Lawrence A., MD Lonn, Eva, MD Ng, Dominic S., MD, PhD Pearson, Glen J., PharmD Yates, Gillian M., MN, NP Stone, James A., MD, PhD Ur, Ehud, MB Published in Canadian journal of cardiology (2013)

“...Abstract Many developments have occurred since the publication of the widely-used 2009 Canadian Cardiovascular Society (CCS) Dyslipidemia guidelines. Here, we...”

Journal Article

Efficacy of Artificial Pancreas Use in Patients With Type 2 Diabetes Using Intensive Insulin Therapy: A Randomized Crossover Pilot Trial

by Taleb, Nadine Carpentier, André C Messier, Virginie Ladouceur, Martin Haidar, Ahmad Rabasa-Lhoret, Rémi Published in Diabetes care (01.07.2019)

Journal Article

HNF4α is a novel regulator of intestinal glucose-dependent insulinotropic polypeptide

by Girard, Romain Darsigny, Mathieu Jones, Christine Maloum-Rami, Faïza Gélinas, Yves Carpentier, André C Laplante, Mathieu Perreault, Nathalie Boudreau, François Published in Scientific reports (12.03.2019)

“...Mutations in the HNF4A gene cause MODY1 and are associated with an increased risk of Type 2 diabetes mellitus. On the other hand, incretins are hormones that...”

Journal Article

Contribution of perfusion to the 11C‐acetate signal in brown adipose tissue assessed by DCE‐MRI and 68Ga‐DOTA PET in a rat model

by Richard, Gabriel Noll, Christophe Archambault, Mélanie Lebel, Réjean Tremblay, Luc Ait‐Mohand, Samia Guérin, Brigitte Blondin, Denis P Carpentier, André C Lepage, Martin Published in Magnetic resonance in medicine (01.03.2021)

“...Purpose Determine if dynamic contrast enhanced (DCE) ‐MRI and/or 68 gallium 1,4,7,10‐tetraazacyclododecane N, N′, N″, N‴‐tretraacetic acid (68Ga‐DOTA) positron...”

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Journal Article

Determination of a pharmacokinetic model for [11C]-acetate in brown adipose tissue

by Richard, Marie Anne Blondin, Denis P Noll, Christophe Lebel, Réjean Lepage, Martin Carpentier, André C Published in EJNMMI research (01.12.2019)

“...[11C]-acetate positron emission tomography is used to assess oxidative metabolism in various tissues including the heart, tumor, and brown adipose tissue. For...”

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Journal Article

Increased myocardial uptake of dietary fatty acids linked to cardiac dysfunction in glucose-intolerant humans

by LABBE, Sébastien M GRENIER-LAROUCHE, Thomas NOLL, Christophe PHOENIX, Serge GUERIN, Brigitte TURCOTTE, Eric E CARPENTIER, André C Published in Diabetes (New York, N.Y.) (2012)

“...Impaired cardiac systolic and diastolic function has been observed in preclinical models and in subjects with type 2 diabetes. Using a recently validated...”

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Journal Article

Omental adipocyte hypertrophy relates to coenzyme Q10 redox state and lipid peroxidation in obese women

by Grenier-Larouche, Thomas Galinier, Anne Casteilla, Louis Carpentier, André C Tchernof, André Published in Journal of lipid research (01.10.2015)

“...Occurrence of oxidative stress in white adipose tissues contributes to its dysfunction and the development of obesity-related metabolic complications. Coenzyme...”

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