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1by Gélinas, Roselle Mailleux, Florence Dontaine, Justine Bultot, Laurent Demeulder, Bénédicte Ginion, Audrey Daskalopoulos, Evangelos P Esfahani, Hrag Dubois-Deruy, Emilie Lauzier, Benjamin Gauthier, Chantal Olson, Aaron K Bouchard, Bertrand Des Rosiers, Christine Viollet, Benoit Sakamoto, Kei Balligand, Jean-Luc Vanoverschelde, Jean-Louis Beauloye, Christophe Horman, Sandrine Bertrand, Luc Published in Nature communications (25.01.2018)“...AMP-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy. Here, we show that submaximal AMPK activation blocks cardiomyocyte...”
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2by Ruiz, Matthieu Labarthe, François Fortier, Annik Bouchard, Bertrand Thompson Legault, Julie Bolduc, Virginie Rigal, Odile Chen, Jane Ducharme, Anique Crawford, Peter A Tardif, Jean-Claude Des Rosiers, Christine Published in American journal of physiology. Heart and circulatory physiology (01.10.2017)“...Heart failure (HF) is associated with metabolic perturbations, particularly of fatty acids (FAs), which remain to be better understood in humans. This study...”
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3by PICARD, Martin JUNG, Boris MATECKI, Stefan JABER, Samir DES ROSIERS, Christine KARPATI, George FERRI, Lorenzo BURELLE, Yan TURNBULL, Douglass M TAIVASSALO, Tanja PETROF, Basil J FENG LIANG AZUELOS, Ilan HUSSAIN, Sabah GOLDBERG, Peter CODIN, Richard DANIALOU, Gawiyou CHATURVEDI, Rakesh RYGIEL, Karolina Published in American journal of respiratory and critical care medicine (2012)“...Mechanical ventilation (MV) is associated with adverse effects on the diaphragm, but the cellular basis for this phenomenon, referred to as ventilator-induced...”
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4by Lamantia, Valérie Bissonnette, Simon Provost, Viviane Devaux, Marie Cyr, Yannick Daneault, Caroline Rosiers, Christine Des Faraj, May Published in The Journal of nutrition (01.01.2019)“...ABSTRACT Background δ-5 and δ-6 desaturases (D5D and D6D) catalyze the endogenous conversion of n–3 (ω-3) and n–6 (ω-6) polyunsaturated fatty acids (PUFAs)...”
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5by Schmeisser, Sebastian Li, Shaolin Bouchard, Bertrand Ruiz, Matthieu Des Rosiers, Christine Roy, Richard Published in Cell reports (Cambridge) (24.12.2019)“...A growing body of evidence suggests that changes in fat metabolism may have a significant effect on lifespan. Accumulation of lipid deposits in non-adipose...”
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6by Kajimoto, Masaki Ledee, Dolena R Olson, Aaron K Isern, Nancy G Des Rosiers, Christine Portman, Michael A Published in American journal of physiology. Heart and circulatory physiology (01.10.2015)“...Nutritional energy support during extracorporeal membrane oxygenation (ECMO) should promote successful myocardial adaptation and eventual weaning from the ECMO...”
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7by Virginie Bolduc Annick Drouin Marc-Antoine Gillis Natacha Duquette Nathalie Thorin-Trescases Isabelle Frayne-Robillard Christine Des Rosiers Jean-Claude Tardif Eric Thorin Published in American Journal of Physiology - Heart and Circulatory Physiology (01.11.2011)“...The cardiac cycle imposes a mechanical stress that dilates elastic carotid arteries, while shear stress largely contributes to the endothelium-dependent...”
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8by Renguet, Edith Ginion, Audrey Gélinas, Roselle Bultot, Laurent Auquier, Julien Robillard Frayne, Isabelle Daneault, Caroline Vanoverschelde, Jean-Louis Des Rosiers, Christine Hue, Louis Horman, Sandrine Beauloye, Christophe Bertrand, Luc Published in American journal of physiology. Heart and circulatory physiology (01.08.2017)“...High plasma leucine levels strongly correlate with type 2 diabetes. Studies of muscle cells have suggested that leucine alters the insulin response for glucose...”
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9by Lacroix, Sébastien Rosiers, Christine Des Tardif, Jean-Claude Nigam, Anil Published in Nutrition research reviews (01.12.2012)“...Endothelial dysfunction is a turning point in the initiation and development of atherosclerosis and its complications and is predictive of future...”
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10by Ruiz, Matthieu Coderre, Lise Lachance, Dominic Houde, Valérie Martel, Cécile Thompson Legault, Julie Gillis, Marc-Antoine Bouchard, Bertrand Daneault, Caroline Carpentier, André C Gaestel, Matthias Allen, Bruce G Des Rosiers, Christine Published in Diabetes (New York, N.Y.) (01.02.2016)“...Heart disease remains a major complication of diabetes, and the identification of new therapeutic targets is essential. This study investigates the role of the...”
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11by Vaillant, Fanny Lauzier, Benjamin Ruiz, Matthieu Shi, Yanfen Lachance, Dominic Rivard, Marie-Eve Bolduc, Virginie Thorin, Eric Tardif, Jean-Claude Des Rosiers, Christine Published in American journal of physiology. Heart and circulatory physiology (01.10.2016)“...While heart rate reduction (HRR) is a target for the management of patients with heart disease, contradictory results were reported using ivabradine, which...”
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12by Alexis Ascah Maya Khairallah Frédéric Daussin Céline Bourcier-Lucas Richard Godin Bruce G. Allen Basil J. Petrof Christine Des Rosiers Yan Burelle Published in American Journal of Physiology - Heart and Circulatory Physiology (01.01.2011)“...Susceptibility of cardiomyocytes to stress-induced damage has been implicated in the development of cardiomyopathy in Duchenne muscular dystrophy, a disease...”
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13by Fanny Vaillant Benjamin Lauzier Isabelle Poirier Roselle Gélinas Marie-Eve Rivard Isabelle Robillard Frayne Eric Thorin Christine Des Rosiers Published in American Journal of Physiology - Heart and Circulatory Physiology (01.01.2014)“...In mice, genetic background is known to influence various parameters, including cardiac function. Its impact on cardiac energy substrate metabolism-a factor...”
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14by Ledee, Dolena R Kajimoto, Masaki O'Kelly Priddy, Colleen M Olson, Aaron K Isern, Nancy Robillard-Frayne, Isabelle Des Rosiers, Christine Portman, Michael A Published in American journal of physiology. Heart and circulatory physiology (01.07.2015)“...Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory support for infants and children with postoperative cardiopulmonary failure...”
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15by Tatiana F. Galvao Ramzi J. Khairallah Erinne R. Dabkowski Bethany H. Brown Peter A. Hecker Kelly A. O'Connell Karen M. O'Shea Hani N. Sabbah Sharad Rastogi Caroline Daneault Christine Des Rosiers William C. Stanley Published in American Journal of Physiology - Heart and Circulatory Physiology (01.01.2013)“...Mitochondrial dysfunction in heart failure includes greater susceptibility to mitochondrial permeability transition (MPT), which may worsen cardiac function...”
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16by Colleen M. O′Kelly Priddy Masaki Kajimoto Dolena R. Ledee Bertrand Bouchard Nancy Isern Aaron K. Olson Christine Des Rosiers Michael A. Portman Published in American Journal of Physiology - Heart and Circulatory Physiology (01.02.2013)“...Extracorporeal membrane oxygenation (ECMO) provides essential mechanical circulatory support necessary for survival in infants and children with acute cardiac...”
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17by Aaron K. Olson Bertrand Bouchard Xue-Han Ning Nancy Isern Christine Des Rosiers Michael A. Portman Published in American Journal of Physiology - Heart and Circulatory Physiology (01.03.2012)“...Triiodothyronine (T3) supplementation improves clinical outcomes in infants after cardiac surgery using cardiopulmonary bypass by unknown mechanisms. We...”
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18by Benjamin Lauzier Fanny Vaillant Roselle Gélinas Bertrand Bouchard Roger Brownsey Eric Thorin Jean-Claude Tardif Christine Des Rosiers Published in American Journal of Physiology - Heart and Circulatory Physiology (01.03.2011)“...Heart rate reduction (HRR) is an important target in the management of patients with chronic stable angina. Most available drugs for HRR, such as β-blockers,...”
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19by Dabkowski, Erinne R O’Connell, Kelly A Xu, Wenhong Ribeiro Jr, Rogerio F Hecker, Peter A Shekar, Kadambari Chandra Daneault, Caroline Des Rosiers, Christine Stanley, William C Published in Cardiovascular drugs and therapy (01.12.2013)“...Supplementation with the n3 polyunsaturated fatty acid docosahexaenoic acid (DHA) is beneficial in heart failure patients, however the mechanisms are unclear...”
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20by Roy W. R. Dudley Maya Khairallah Shawn Mohammed Larry Lands Christine Des Rosiers Basil J. Petrof Published in American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (01.09.2006)“...The precise mechanisms underlying skeletal muscle damage in Duchenne muscular dystrophy (DMD) remain ill-defined. Functional ischemia during muscle activation,...”