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  • Your search results: "DES ROSIERS, Christine"
Showing 1 - 20 results of 273 for search '"DES ROSIERS, Christine"', query time: 1.83s Narrow search
  • 1
    Cover Image Journal Article
    AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation
    by Gélinas, Roselle   Mailleux, Florence   Dontaine, Justine   Bultot, Laurent   Demeulder, Bénédicte   Ginion, Audrey   Daskalopoulos, Evangelos P   Esfahani, Hrag   Dubois-Deruy, Emilie   Lauzier, Benjamin   Gauthier, Chantal   Olson, Aaron K   Bouchard, Bertrand   Des Rosiers, Christine   Viollet, Benoit   Sakamoto, Kei   Balligand, Jean-Luc   Vanoverschelde, Jean-Louis   Beauloye, Christophe   Horman, Sandrine   Bertrand, Luc Published in Nature communications (25.01.2018)
    “...AMP-activated protein kinase (AMPK) has been shown to inhibit cardiac hypertrophy. Here, we show that submaximal AMPK activation blocks cardiomyocyte...”
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  • 2
    Cover Image Journal Article
    Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond
    by Ruiz, Matthieu   Labarthe, François   Fortier, Annik   Bouchard, Bertrand   Thompson Legault, Julie   Bolduc, Virginie   Rigal, Odile   Chen, Jane   Ducharme, Anique   Crawford, Peter A   Tardif, Jean-Claude   Des Rosiers, Christine Published in American journal of physiology. Heart and circulatory physiology (01.10.2017)
    “...Heart failure (HF) is associated with metabolic perturbations, particularly of fatty acids (FAs), which remain to be better understood in humans. This study...”
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  • 3
    Cover Image Journal Article
    Mitochondrial dysfunction and lipid accumulation in the human diaphragm during mechanical ventilation
    by PICARD, Martin   JUNG, Boris   MATECKI, Stefan   JABER, Samir   DES ROSIERS, Christine   KARPATI, George   FERRI, Lorenzo   BURELLE, Yan   TURNBULL, Douglass M   TAIVASSALO, Tanja   PETROF, Basil J   FENG LIANG   AZUELOS, Ilan   HUSSAIN, Sabah   GOLDBERG, Peter   CODIN, Richard   DANIALOU, Gawiyou   CHATURVEDI, Rakesh   RYGIEL, Karolina Published in American journal of respiratory and critical care medicine (2012)
    “...Mechanical ventilation (MV) is associated with adverse effects on the diaphragm, but the cellular basis for this phenomenon, referred to as ventilator-induced...”
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  • 4
    Cover Image Journal Article
    The Association of Polyunsaturated Fatty Acid δ-5-Desaturase Activity with Risk Factors for Type 2 Diabetes Is Dependent on Plasma ApoB-Lipoproteins in Overweight and Obese Adults
    by Lamantia, Valérie   Bissonnette, Simon   Provost, Viviane   Devaux, Marie   Cyr, Yannick   Daneault, Caroline   Rosiers, Christine Des   Faraj, May Published in The Journal of nutrition (01.01.2019)
    “...ABSTRACT Background δ-5 and δ-6 desaturases (D5D and D6D) catalyze the endogenous conversion of n–3 (ω-3) and n–6 (ω-6) polyunsaturated fatty acids (PUFAs)...”
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  • 5
    Cover Image Journal Article
    Muscle-Specific Lipid Hydrolysis Prolongs Lifespan through Global Lipidomic Remodeling
    by Schmeisser, Sebastian   Li, Shaolin   Bouchard, Bertrand   Ruiz, Matthieu   Des Rosiers, Christine   Roy, Richard Published in Cell reports (Cambridge) (24.12.2019)
    “...A growing body of evidence suggests that changes in fat metabolism may have a significant effect on lifespan. Accumulation of lipid deposits in non-adipose...”
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  • 6
    Cover Image Journal Article
    Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporeal membrane oxygenation in an infant swine model
    by Kajimoto, Masaki   Ledee, Dolena R   Olson, Aaron K   Isern, Nancy G   Des Rosiers, Christine   Portman, Michael A Published in American journal of physiology. Heart and circulatory physiology (01.10.2015)
    “...Nutritional energy support during extracorporeal membrane oxygenation (ECMO) should promote successful myocardial adaptation and eventual weaning from the ECMO...”
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  • 7
    Cover Image Journal Article
    Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice
    by Virginie Bolduc   Annick Drouin   Marc-Antoine Gillis   Natacha Duquette   Nathalie Thorin-Trescases   Isabelle Frayne-Robillard   Christine Des Rosiers   Jean-Claude Tardif   Eric Thorin Published in American Journal of Physiology - Heart and Circulatory Physiology (01.11.2011)
    “...The cardiac cycle imposes a mechanical stress that dilates elastic carotid arteries, while shear stress largely contributes to the endothelium-dependent...”
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  • 8
    Cover Image Journal Article
    Metabolism and acetylation contribute to leucine-mediated inhibition of cardiac glucose uptake
    by Renguet, Edith   Ginion, Audrey   Gélinas, Roselle   Bultot, Laurent   Auquier, Julien   Robillard Frayne, Isabelle   Daneault, Caroline   Vanoverschelde, Jean-Louis   Des Rosiers, Christine   Hue, Louis   Horman, Sandrine   Beauloye, Christophe   Bertrand, Luc Published in American journal of physiology. Heart and circulatory physiology (01.08.2017)
    “...High plasma leucine levels strongly correlate with type 2 diabetes. Studies of muscle cells have suggested that leucine alters the insulin response for glucose...”
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  • 9
    Cover Image Journal Article
    The role of oxidative stress in postprandial endothelial dysfunction
    by Lacroix, Sébastien   Rosiers, Christine Des   Tardif, Jean-Claude   Nigam, Anil Published in Nutrition research reviews (01.12.2012)
    “...Endothelial dysfunction is a turning point in the initiation and development of atherosclerosis and its complications and is predictive of future...”
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  • 10
    Cover Image Journal Article
    MK2 Deletion in Mice Prevents Diabetes-Induced Perturbations in Lipid Metabolism and Cardiac Dysfunction
    by Ruiz, Matthieu   Coderre, Lise   Lachance, Dominic   Houde, Valérie   Martel, Cécile   Thompson Legault, Julie   Gillis, Marc-Antoine   Bouchard, Bertrand   Daneault, Caroline   Carpentier, André C   Gaestel, Matthias   Allen, Bruce G   Des Rosiers, Christine Published in Diabetes (New York, N.Y.) (01.02.2016)
    “...Heart disease remains a major complication of diabetes, and the identification of new therapeutic targets is essential. This study investigates the role of the...”
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  • 11
    Cover Image Journal Article
    Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia
    by Vaillant, Fanny   Lauzier, Benjamin   Ruiz, Matthieu   Shi, Yanfen   Lachance, Dominic   Rivard, Marie-Eve   Bolduc, Virginie   Thorin, Eric   Tardif, Jean-Claude   Des Rosiers, Christine Published in American journal of physiology. Heart and circulatory physiology (01.10.2016)
    “...While heart rate reduction (HRR) is a target for the management of patients with heart disease, contradictory results were reported using ivabradine, which...”
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  • 12
    Cover Image Journal Article
    Stress-induced opening of the permeability transition pore in the dystrophin-deficient heart is attenuated by acute treatment with sildenafil
    by Alexis Ascah   Maya Khairallah   Frédéric Daussin   Céline Bourcier-Lucas   Richard Godin   Bruce G. Allen   Basil J. Petrof   Christine Des Rosiers   Yan Burelle Published in American Journal of Physiology - Heart and Circulatory Physiology (01.01.2011)
    “...Susceptibility of cardiomyocytes to stress-induced damage has been implicated in the development of cardiomyopathy in Duchenne muscular dystrophy, a disease...”
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  • 13
    Cover Image Journal Article
    Mouse strain differences in metabolic fluxes and function of ex vivo working hearts
    by Fanny Vaillant   Benjamin Lauzier   Isabelle Poirier   Roselle Gélinas   Marie-Eve Rivard   Isabelle Robillard Frayne   Eric Thorin   Christine Des Rosiers Published in American Journal of Physiology - Heart and Circulatory Physiology (01.01.2014)
    “...In mice, genetic background is known to influence various parameters, including cardiac function. Its impact on cardiac energy substrate metabolism-a factor...”
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  • 14
    Cover Image Journal Article
    Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model
    by Ledee, Dolena R   Kajimoto, Masaki   O'Kelly Priddy, Colleen M   Olson, Aaron K   Isern, Nancy   Robillard-Frayne, Isabelle   Des Rosiers, Christine   Portman, Michael A Published in American journal of physiology. Heart and circulatory physiology (01.07.2015)
    “...Extracorporeal membrane oxygenation (ECMO) provides mechanical circulatory support for infants and children with postoperative cardiopulmonary failure...”
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  • 15
    Cover Image Journal Article
    Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival
    by Tatiana F. Galvao   Ramzi J. Khairallah   Erinne R. Dabkowski   Bethany H. Brown   Peter A. Hecker   Kelly A. O'Connell   Karen M. O'Shea   Hani N. Sabbah   Sharad Rastogi   Caroline Daneault   Christine Des Rosiers   William C. Stanley Published in American Journal of Physiology - Heart and Circulatory Physiology (01.01.2013)
    “...Mitochondrial dysfunction in heart failure includes greater susceptibility to mitochondrial permeability transition (MPT), which may worsen cardiac function...”
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  • 16
    Cover Image Journal Article
    Myocardial oxidative metabolism and protein synthesis during mechanical circulatory support by extracorporeal membrane oxygenation
    by Colleen M. O′Kelly Priddy   Masaki Kajimoto   Dolena R. Ledee   Bertrand Bouchard   Nancy Isern   Aaron K. Olson   Christine Des Rosiers   Michael A. Portman Published in American Journal of Physiology - Heart and Circulatory Physiology (01.02.2013)
    “...Extracorporeal membrane oxygenation (ECMO) provides essential mechanical circulatory support necessary for survival in infants and children with acute cardiac...”
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  • 17
    Cover Image Journal Article
    Triiodothyronine increases myocardial function and pyruvate entry into the citric acid cycle after reperfusion in a model of infant cardiopulmonary bypass
    by Aaron K. Olson   Bertrand Bouchard   Xue-Han Ning   Nancy Isern   Christine Des Rosiers   Michael A. Portman Published in American Journal of Physiology - Heart and Circulatory Physiology (01.03.2012)
    “...Triiodothyronine (T3) supplementation improves clinical outcomes in infants after cardiac surgery using cardiopulmonary bypass by unknown mechanisms. We...”
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  • 18
    Cover Image Journal Article
    Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts
    by Benjamin Lauzier   Fanny Vaillant   Roselle Gélinas   Bertrand Bouchard   Roger Brownsey   Eric Thorin   Jean-Claude Tardif   Christine Des Rosiers Published in American Journal of Physiology - Heart and Circulatory Physiology (01.03.2011)
    “...Heart rate reduction (HRR) is an important target in the management of patients with chronic stable angina. Most available drugs for HRR, such as β-blockers,...”
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  • 19
    Cover Image Journal Article
    Docosahexaenoic Acid Supplementation Alters Key Properties of Cardiac Mitochondria and Modestly Attenuates Development of Left Ventricular Dysfunction in Pressure Overload-Induced...
    by Dabkowski, Erinne R   O’Connell, Kelly A   Xu, Wenhong   Ribeiro Jr, Rogerio F   Hecker, Peter A   Shekar, Kadambari Chandra   Daneault, Caroline   Des Rosiers, Christine   Stanley, William C Published in Cardiovascular drugs and therapy (01.12.2013)
    “...Supplementation with the n3 polyunsaturated fatty acid docosahexaenoic acid (DHA) is beneficial in heart failure patients, however the mechanisms are unclear...”
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  • 20
    Cover Image Journal Article
    Dynamic responses of the glutathione system to acute oxidative stress in dystrophic mouse (mdx) muscles
    by Roy W. R. Dudley   Maya Khairallah   Shawn Mohammed   Larry Lands   Christine Des Rosiers   Basil J. Petrof Published in American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (01.09.2006)
    “...The precise mechanisms underlying skeletal muscle damage in Duchenne muscular dystrophy (DMD) remain ill-defined. Functional ischemia during muscle activation,...”
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