Search Results - "Dimitrov, Ivan"

Journal Article

AllerTOP—a server for in silico prediction of allergens

by Dimitrov, Ivan Flower, Darren R Doytchinova, Irini Published in BMC bioinformatics (2013-00-00)

“...Allergy is a form of hypersensitivity to normally innocuous substances, such as dust, pollen, foods or drugs. Allergens are small antigens that commonly...”

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Associations between Milk and Egg Allergens and the HLA-DRB1/DQ Polymorphism: A Bioinformatics Approach

by Dimitrov, Ivan Doytchinova, Irini Published in International archives of allergy and immunology (01.04.2016)

“...Background: Little is known about the associations between human leukocyte antigens (HLAs) and food allergies. Our aim was to analyze the associations between...”

Journal Article

Proteochemometrics-Based Prediction of Peptide Binding to HLA-DP Proteins

by Yordanov, Ventsislav Dimitrov, Ivan Doytchinova, Irini Published in Journal of chemical information and modeling (26.02.2018)

“...Human leukocyte antigens (HLA) class II proteins are involved in the antigen processing in the antigen presenting cells. They form complexes with antigen...”

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Journal Article

Cellular polyamines condense hyperphosphorylated Tau, triggering Alzheimer’s disease

by Ivanov, Stefan M Atanasova, Mariyana Dimitrov, Ivan Doytchinova, Irini A Published in Scientific reports (22.06.2020)

“...Many gaps in our understanding of Alzheimer’s disease remain despite intense research efforts. One such prominent gap is the mechanism of Tau condensation and...”

Journal Article

Predicting Immunogenicity Risk in Biopharmaceuticals

by Doneva, Nikolet Doytchinova, Irini Dimitrov, Ivan Published in Symmetry (Basel) (27.02.2021)

“...The assessment of immunogenicity of biopharmaceuticals is a crucial step in the process of their development. Immunogenicity is related to the activation of...”

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Journal Article

Z‐spectrum appearance and interpretation in the presence of fat: Influence of acquisition parameters

by Zhang, Shu Keupp, Jochen Wang, Xinzeng Dimitrov, Ivan Madhuranthakam, Ananth J Lenkinski, Robert E Vinogradov, Elena Published in Magnetic resonance in medicine (01.05.2018)

“...Purpose Chemical exchange saturation transfer (CEST) MRI is increasingly evolving from brain to body applications. One of the known problems in the body...”

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Journal Article

Positive Systems of Kostant Roots

by Dimitrov, Ivan Roth, Mike Published in Algebras and representation theory (01.12.2017)

“...Let 𝔤 $\mathfrak {g}$ be a simple complex Lie algebra and let 𝔱 ⊂ 𝔤 $\mathfrak {t} \subset \mathfrak {g}$ be a toral subalgebra of 𝔤 $\mathfrak {g}$ . As a...”

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Journal Article

INTERSECTION MULTIPLICITY ONE FOR CLASSICAL GROUPS

by DIMITROV, IVAN ROTH, MIKE Published in Transformation groups (01.12.2019)

“...In this note we show that when G is a classical semi-simple algebraic group, B a G a Borel subgroup, and X = G/B, then the structure coefficients of the...”

Journal Article

Bacterial Immunogenicity Prediction by Machine Learning Methods

by Dimitrov, Ivan Zaharieva, Nevena Doytchinova, Irini Published in Vaccines (Basel) (30.11.2020)

“...The identification of protective immunogens is the most important and vigorous initial step in the long-lasting and expensive process of vaccine design and...”

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Journal Article

Two Faces of Milk Proteins Peptides with Both Allergenic and Multidimensional Health Beneficial Impact- Integrated In Vitro / In Silico Approach

by Ogrodowczyk, Anna Maria Dimitrov, Ivan Wróblewska, Barbara Published in Foods (14.01.2021)

“...The main food-origin antigens that the infant's body is in contact with are cow's milk proteins (CMP). Still, CMP are one of the main sources of beneficial...”

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Journal Article

Dependence of blood T2 on oxygenation at 7 T: In vitro calibration and in vivo application

by Krishnamurthy, Lisa C Liu, Peiying Xu, Feng Uh, Jinsoo Dimitrov, Ivan Lu, Hanzhang Published in Magnetic resonance in medicine (01.06.2014)

“...Purpose The calibratable relationship between blood oxygenation (Y) and T2 allows quantification of cerebral venous oxygenation. We aim to establish a...”

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Journal Article

Curcumin Inhibits the Primary Nucleation of Amyloid-Beta Peptide: A Molecular Dynamics Study

by Doytchinova, Irini Atanasova, Mariyana Salamanova, Evdokiya Ivanov, Stefan Dimitrov, Ivan Published in Biomolecules (Basel, Switzerland) (15.09.2020)

“...The amyloid plaques are a key hallmark of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Amyloidogenesis is a complex...”

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Journal Article

Multisite evaluations of a T2‐relaxation‐under‐spin‐tagging (TRUST) MRI technique to measure brain oxygenation

by Liu, Peiying Dimitrov, Ivan Andrews, Trevor Crane, David E Dariotis, Jacinda K Desmond, John Dumas, Julie Gilbert, Guillaume Kumar, Anand Maclntosh, Bradley J Tucholka, Alan Yang, Shaolin Xiao, Guanghua Lu, Hanzhang Published in Magnetic resonance in medicine (01.02.2016)

“...Purpose Venous oxygenation (Yv) is an important index of brain physiology and may be indicative of brain diseases. A T2‐relaxation‐under‐spin‐tagging (TRUST)...”

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Journal Article

Quadrature transmit coil for breast imaging at 7 tesla using forced current excitation for improved homogeneity

by McDougall, Mary Preston Cheshkov, Sergey Rispoli, Joseph Malloy, Craig Dimitrov, Ivan Wright, Steven M Published in Journal of magnetic resonance imaging (01.11.2014)

“...Purpose To demonstrate the use of forced current excitation (FCE) to create homogeneous excitation of the breast at 7 tesla, insensitive to the effects of...”

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Journal Article

Novel hits for acetylcholinesterase inhibition derived by docking-based screening on ZINC database

by Doytchinova, Irini Atanasova, Mariyana Valkova, Iva Stavrakov, Georgi Philipova, Irena Zhivkova, Zvetanka Zheleva-Dimitrova, Dimitrina Konstantinov, Spiro Dimitrov, Ivan Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2018)

“...The inhibition of the enzyme acetylcholinesterase (AChE) increases the levels of the neurotransmitter acetylcholine and symptomatically improves the affected...”

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Journal Article

Quantification of renal steatosis in type II diabetes mellitus using dixon‐based MRI

by Yokoo, Takeshi Clark, Haley R Pedrosa, Ivan Yuan, Qing Dimitrov, Ivan Zhang, Yue Lingvay, Ildiko Beg, Muhammad S Bobulescu, I. Alexandru Published in Journal of magnetic resonance imaging (01.11.2016)

“...Purpose To evaluate renal lipid content in subjects with and without type II diabetes mellitus (DM2) using Dixon‐based magnetic resonance imaging (MRI)...”

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Journal Article

Proteochemometrics for the Prediction of Binding to the MHC Proteins

by Ventsislav Yordanov Ivan Dimitrov Irini Doytchinova Published in Letters in drug design & discovery (20170000)

“...The recognition of a foreign protein (antigen) by host B and/or T cells and the induction of immune response have a key role for the human immune system. The...”

Journal Article

Accelerated rates of protein evolution in barley grain and pistil biased genes might be legacy of domestication

by Shi, Tao Dimitrov, Ivan Zhang, Yinling Tax, Frans E Yi, Jing Gou, Xiaoping Li, Jia Published in Plant molecular biology (01.10.2015)

“...Traits related to grain and reproductive organs in grass crops have been under continuous directional selection during domestication. Barley is one of the...”

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Journal Article

Glycine by MR spectroscopy is an imaging biomarker of glioma aggressiveness

by Tiwari, Vivek Daoud, Elena V Hatanpaa, Kimmo J Gao, Ang Zhang, Song An, Zhongxu Ganji, Sandeep K Raisanen, Jack M Lewis, Cheryl M Askari, Pegah Baxter, Jeannie Levy, Michael Dimitrov, Ivan Thomas, Binu P Pinho, Marco C Madden, Christopher J Pan, Edward Patel, Toral R DeBerardinis, Ralph J Sherry, A Dean Mickey, Bruce E Malloy, Craig R Maher, Elizabeth A Choi, Changho Published in Neuro-oncology (Charlottesville, Va.) (07.07.2020)

“...Abstract Background High-grade gliomas likely remodel the metabolic machinery to meet the increased demands for amino acids and nucleotides during rapid cell...”

Journal Article

Spontaneous perforation of the bladder in a patient operated for a lung abscess: a case report

by Hadzhiminev, Velizar Kalacheva, Krasi Dimitrov, Ivan Novakov, Ivan Published in International Journal of Surgery and Medicine (2017-00-00)

“...We present a rare case of a spontaneous perforation of the bladder in a female patient who underwent thoracic operation. A 45 year-old female patient with no...”

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