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1
Journal Article
by Murtomäki, Aino Pollard, Jeffrey W Nurmi, Harri Zarkada, Georgia Fruttiger, Marcus Mäkinen, Taija Gerhardt, Holger Zheng, Wei Tammela, Tuomas Franco, Claudio A Miura, Naoyuki Ylä-Herttuala, Seppo Eichmann, Anne Tvorogov, Denis Jakobsson, Lars Aranda, Evelyn Heinolainen, Krista Alitalo, Kari Published in Nature cell biology (11.09.2011)“...Angiogenesis, the growth of new blood vessels, involves specification of endothelial cells to tip cells and stalk cells, which is controlled by Notch...”
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2
Journal Article
by Papadopoulos, Nicholas Martin, Joel Ruan, Qin Rafique, Ashique Rosconi, Michael P Shi, Ergang Pyles, Erica A Yancopoulos, George D Stahl, Neil Wiegand, Stanley J Published in Angiogenesis (London) (01.06.2012)“...Pharmacological inhibition of VEGF-A has proven to be effective in inhibiting angiogenesis and vascular leak associated with cancers and various eye diseases...”
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3
Journal Article
by Heinolainen, Krista Karaman, Sinem D’Amico, Gabriela Tammela, Tuomas Sormunen, Raija Eklund, Lauri Alitalo, Kari Zarkada, Georgia Published in Circulation research (28.04.2017)“...RATIONALE:Vascular endothelial growth factor (VEGF) is the main driver of angiogenesis and vascular permeability via VEGF receptor 2 (VEGFR2), whereas...”
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4
Journal Article
by Shibuya, Masabumi Published in Journal of biochemistry (Tokyo) (01.01.2013)“...Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor supergene family, and they play central roles in the regulation of...”
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5
Journal Article
by Cho, Sun-Jung Park, Moon Ho Han, Changsu Yoon, Keejung Koh, Young Ho Published in Scientific reports (18.12.2017)“...Alzheimer's disease (AD) is a common disorder of progressive cognitive decline among elderly subjects. Angiogenesis-related factors including vascular...”
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6
Journal Article
by Anisimov, Andrey Leppänen, Veli-Matti Tvorogov, Denis Zarkada, Georgia Jeltsch, Michael Holopainen, Tanja Kaijalainen, Seppo Alitalo, Kari Published in Science signaling (02.07.2013)“...Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel development through VEGF receptors (VEGFRs). The VEGFR immunoglobulin homology...”
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7
Journal Article
by Veli-Matti Leppänen Andrea E. Prota Michael Jeltsch Andrey Anisimov Nisse Kalkkinen Tomas Strandin Hilkka Lankinen Adrian Goldman Kurt Ballmer-Hofer Kari Alitalo Erkki Ruoslahti Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2010)“...Vascular endothelial growth factors (VEGFs) regulate blood and lymph vessel formation through activation of three receptor tyrosine kinases, VEGFR-1, -2, and...”
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8
Journal Article
by Coon, Brian G Baeyens, Nicolas Han, Jinah Budatha, Madhusudhan Ross, Tyler D Fang, Jennifer S Yun, Sanguk Thomas, Jeon-Leon Schwartz, Martin A Published in The Journal of cell biology (30.03.2015)“...Endothelial responses to fluid shear stress are essential for vascular development and physiology, and determine the formation of atherosclerotic plaques at...”
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9
Journal Article
by Davydova, Natalia Harris, Nicole C Roufail, Sally Paquet-Fifield, Sophie Ishaq, Musarat Streltsov, Victor A Williams, Steven P Karnezis, Tara Stacker, Steven A Achen, Marc G Published in The Journal of biological chemistry (01.12.2016)“...VEGF-C and VEGF-D are secreted glycoproteins that induce angiogenesis and lymphangiogenesis in cancer, thereby promoting tumor growth and spread. They exhibit...”
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10
Journal Article
“...Angiogenesis is a highly regulated process orchestrated by the VEGF system. Heparin/heparan sulfate proteoglycans and neuropilin-1 (NRP-1) have been identified...”
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11
Journal Article
by Durré, Tania Morfoisse, Florent Erpicum, Charlotte Ebroin, Marie Blacher, Silvia García-Caballero, Melissa Deroanne, Christophe Louis, Thomas Balsat, Cédric Van de Velde, Maureen Kaijalainen, Seppo Kridelka, Frédéric Engelholm, Lars Struman, Ingrid Alitalo, Kari Behrendt, Niels Paupert, Jenny Noel, Agnès Published in Nature communications (05.12.2018)“...The development of new lymphatic vessels occurs in many cancerous and inflammatory diseases through the binding of VEGF-C to its receptors, VEGFR-2 and...”
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12
Journal Article
by Gaudio, Eugenio Barbaro, Barbara Alvaro, Domenico Glaser, Shannon Francis, Heather Ueno, Yoshiyuki Meininger, Cynthia J Franchitto, Antonio Onori, Paolo Marzioni, Marco Taffetani, Silvia Fava, Giammarco Stoica, George Venter, Julie Reichenbach, Ramona De Morrow, Sharon Summers, Ryun Alpini, Gianfranco Published in Gastroenterology (New York, N.Y. 1943) (01.04.2006)“...Background & Aims: Vascular endothelial growth factor (VEGF) is secreted by several epithelia and modulates cellular functions by autocrine and paracrine...”
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13
Journal Article
by de Paulis, Amato Prevete, Nella Fiorentino, Isabella Rossi, Francesca Wanda Staibano, Stefania Montuori, Nunzia Ragno, Pia Longobardi, Amelia Liccardo, Bianca Genovese, Arturo Ribatti, Domenico Walls, Andrew F Marone, Gianni Published in The Journal of immunology (1950) (15.11.2006)“...Angiogenesis is a multistep complex phenomenon critical for several inflammatory and neoplastic disorders. Basophils, normally confined to peripheral blood,...”
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14
Journal Article
by Liu, Yanqiu Berendsen, Agnes D Jia, Shidong Lotinun, Sutada Baron, Roland Ferrara, Napoleone Olsen, Bjorn R Published in The Journal of clinical investigation (01.09.2012)“...Osteoporotic bones have reduced spongy bone mass, altered bone architecture, and increased marrow fat. Bone marrow stem cells from osteoporotic patients are...”
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15
Journal Article
by BENEDITO, Rui ROCHA, Susana F WOESTE, Marina ZAMYKAL, Martin RADTKE, Freddy CASANOVAS, Oriol DUARTE, Antonio PYTOWSKI, Bronislaw ADAMS, Ralf H Published in Nature (London) (2012)“...Developing tissues and growing tumours produce vascular endothelial growth factors (VEGFs), leading to the activation of the corresponding receptors in...”
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16
Journal Article
by Singh, Nikhlesh K Hansen, 3rd, Dale E Kundumani-Sridharan, Venkatesh Rao, Gadiparthi N Published in Blood (07.03.2013)“...To understand the mechanisms of Src-PLD1-PKCγ-cPLA2 activation by vascular endothelial growth factor A (VEGFA), we studied the role of Kdr and Flt1. VEGFA,...”
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17
Journal Article
by Shibuya, Masabumi Published in Cold Spring Harbor perspectives in biology (01.10.2013)“...Vascular endothelial growth factor receptors (VEGFRs) in vertebrates play essential roles in the regulation of angiogenesis and lymphangiogenesis. VEGFRs...”
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18
Journal Article
Neuroblastoma progression correlates with downregulation of the lymphangiogenesis inhibitor sVEGFR-2by BECKER, Jürgen PAVLAKOVIC, Helena LUDEWIG, Fabian WILTING, Fabiola WEICH, Herbert A ALBUQUERQUE, Romulo AMBATI, Jayakrishna WILTING, Jörg Published in Clinical cancer research (2010)“...Tumor progression correlates with the induction of a dense supply of blood vessels and the formation of peritumoral lymphatics. Hemangiogenesis and...”
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19
Journal Article
by Bower, Neil I Vogrin, Adam J Le Guen, Ludovic Chen, Huijun Stacker, Steven A Achen, Marc G Hogan, Benjamin M Published in Development (Cambridge) (01.02.2017)“...Vascular endothelial growth factors (VEGFs) control angiogenesis and lymphangiogenesis during development and in pathological conditions. In the zebrafish...”
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20
Journal Article
by Huggenberger, Reto Ullmann, Stefan Proulx, Steven T Pytowski, Bronislaw Alitalo, Kari Detmar, Michael Published in The Journal of experimental medicine (27.09.2010)“...The role of lymphangiogenesis in inflammation has remained unclear. To investigate the role of lymphatic versus blood vasculature in chronic skin inflammation,...”
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