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1“...Niacin has beneficial effects on plasma lipoproteins and has demonstrated clinical benefits in reducing cardiovascular events and atherosclerosis progression...”
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2by Moriarty, Patrick M., MD Thompson, Paul D., MD Cannon, Christopher P., MD Guyton, John R., MD Bergeron, Jean, MD Zieve, Franklin J., MD, PhD Bruckert, Eric, MD Jacobson, Terry A., MD Kopecky, Stephen L., MD Baccara-Dinet, Marie T., MD Du, Yunling, PhD Pordy, Robert, MD Gipe, Daniel A., MD Published in Journal of clinical lipidology (2015)“...Background Statin intolerance limits many patients from achieving optimal low-density lipoprotein cholesterol (LDL-C) concentrations. Current options for such...”
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3by Langslet, Gisle Hovingh, G. Kees Guyton, John R Baccara-Dinet, Marie T Letierce, Alexia Manvelian, Garen Farnier, Michel Published in Cardiovascular drugs and therapy (2020)“...Purpose: During the alirocumab open-label extension study ODYSSEY OLE (open-label extension; NCT01954394), physicians could adjust alirocumab dosing for...”
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4by Moriarty, Patrick M., MD Jacobson, Terry A., MD Bruckert, Eric, MD Thompson, Paul D., MD Guyton, John R., MD Baccara-Dinet, Marie T., MD Gipe, Daniel, MD Published in Journal of clinical lipidology (2014)“...Background Statin intolerance has been a major limitation in the use of statins, especially at higher doses. New effective treatments are needed for lowering...”
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5by John Guyton Pat Langetieg Day Manoli Mark Payne Brenda Schafer Michael Sebastiani Published in The American economic review (01.05.2017)“...This project uses third-party information reporting and population-level administrative tax data to identify the population of nonfilers. This population...”
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6by Guyton, John R., MD, FNLA Bays, Harold E., MD, FNLA Grundy, Scott M., MD, PhD, FNLA Jacobson, Terry A., MD, FACP, FNLA Published in Journal of clinical lipidology (2014)“...Abstract This article from the National Lipid Association Statin Intolerance Panel provides a framework for understanding statin intolerance and makes general...”
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9by Mosca, Lori, MD, MPH, PhD Ballantyne, Christie M., MD Bays, Harold E., MD Guyton, John R., MD Philip, Sephy, RPh, PharmD Doyle, Ralph T., BA Juliano, Rebecca A., PhD Published in The American journal of cardiology (2016)“...There are limited data on the efficacy and safety of triglyceride (TG)-lowering agents in women. We conducted subgroup analyses of the effects of icosapent...”
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10by Sun, Hanyu Newsome, Jocelyn McNulty, Jennifer Levin, Kerry Langetieg, Pat Schafer, Brenda Guyton, John Published in Field methods (01.08.2020)“...Over the past few decades, the survey industry has experienced a steady decline in response rates, which has posed numerous challenges for researchers, most...”
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11by Guyton, John R., MD Brown, B. Greg, MD, PhD Fazio, Sergio, MD, PhD Polis, Adam, MA Tomassini, Joanne E., PhD Tershakovec, Andrew M., MD, MPH Published in Journal of the American College of Cardiology (2008)“...Lipid-Altering Efficacy and Safety of Ezetimibe/Simvastatin Coadministered With Extended-Release Niacin in Patients With Type IIa or Type IIb Hyperlipidemia...”
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14by Maki, Kevin C., PhD, FNLA Guyton, John R., MD, FNLA Orringer, Carl E., MD, FNLA Hamilton-Craig, Ian, MBBS, PhD Alexander, Dominik D., PhD, MSPH Davidson, Michael H., MD, FNLA Published in Journal of clinical lipidology (2016)“...Background Cardiovascular outcomes trials of fibrates, niacin, or omega-3 fatty acids alone, or added to a statin, have not consistently demonstrated reduced...”
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15by Jacobson, Terry A., MD Armani, Annemarie, MD McKenney, James M., PharmD Guyton, John R., MD Published in The American journal of cardiology (2007)“...Gastrointestinally active agents such as cholesterol absorption inhibitors (CAIs) (eg, ezetimibe) and bile acid sequestrants (BAS) (the resins cholestyramine...”
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16by Ginsberg, Henry N Rader, Daniel J Raal, Frederick J Guyton, John R Baccara-Dinet, Marie T Lorenzato, Christelle Pordy, Robert Stroes, Erik Published in Cardiovascular drugs and therapy (2016)“...Even with statins and other lipid-lowering therapy (LLT), many patients with heterozygous familial hypercholesterolemia (heFH) continue to have elevated...”
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17by Fazio, Sergio, MD, PhD Guyton, John R., MD Polis, Adam B., MA Adewale, Adeniyi J., PhD Tomassini, Joanne E., PhD Ryan, Nicholas W., PharmD Tershakovec, Andrew M., MD, MPH Published in The American journal of cardiology (2010)“...The safety and efficacy of combination ezetimibe/simvastatin (E/S) plus extended-release niacin was assessed in 942 patients with type IIa/IIb hyperlipidemia...”
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19by Chiba-Falek, Ornit Linnertz, Colton Guyton, John Gardner, Stephen D Roses, Allen D McCarthy, Jeanette J Patel, Keyur Published in Human genetics (01.12.2012)“...Hepatitis C virus (HCV) modulates host lipid metabolism as part of its lifecycle and is dependent upon VLDL for co-assembly and secretion. HCV dyslipidemia is...”
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20by Connelly, Margery A Velez Rivera, Jonathan Guyton, John R Siddiqui, Mohammad Shadab Sanyal, Arun J Published in Alimentary pharmacology & therapeutics (01.08.2020)“...Summary Background Patients with non‐alcoholic fatty liver disease (NAFLD), the most common cause of chronic liver disease, are at higher risk of...”