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  • Your search results: "Guyton, John"
Showing 1 - 20 results of 370 for search '"Guyton, John"', query time: 1.29s Narrow search
  • 1
    Cover Image Journal Article
    Safety Considerations with Niacin Therapy
    by Guyton, John R., MD   Bays, Harold E., MD Published in The American journal of cardiology (2007)
    “...Niacin has beneficial effects on plasma lipoproteins and has demonstrated clinical benefits in reducing cardiovascular events and atherosclerosis progression...”
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  • 2
    Cover Image Journal Article
    Efficacy and safety of alirocumab vs ezetimibe in statin-intolerant patients, with a statin rechallenge arm: The ODYSSEY ALTERNATIVE randomized trial
    by Moriarty, Patrick M., MD   Thompson, Paul D., MD   Cannon, Christopher P., MD   Guyton, John R., MD   Bergeron, Jean, MD   Zieve, Franklin J., MD, PhD   Bruckert, Eric, MD   Jacobson, Terry A., MD   Kopecky, Stephen L., MD   Baccara-Dinet, Marie T., MD   Du, Yunling, PhD   Pordy, Robert, MD   Gipe, Daniel A., MD Published in Journal of clinical lipidology (2015)
    “...Background Statin intolerance limits many patients from achieving optimal low-density lipoprotein cholesterol (LDL-C) concentrations. Current options for such...”
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  • 3
    Cover Image Journal Article
    Regional Variations in Alirocumab Dosing Patterns in Patients with Heterozygous Familial Hypercholesterolemia During an Open-Label Extension Study
    by Langslet, Gisle   Hovingh, G. Kees   Guyton, John R   Baccara-Dinet, Marie T   Letierce, Alexia   Manvelian, Garen   Farnier, Michel Published in Cardiovascular drugs and therapy (2020)
    “...Purpose: During the alirocumab open-label extension study ODYSSEY OLE (open-label extension; NCT01954394), physicians could adjust alirocumab dosing for...”
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  • 4
    Cover Image Journal Article
    Efficacy and safety of alirocumab, a monoclonal antibody to PCSK9, in statin-intolerant patients: Design and rationale of ODYSSEY ALTERNATIVE, a randomized phase 3 trial
    by Moriarty, Patrick M., MD   Jacobson, Terry A., MD   Bruckert, Eric, MD   Thompson, Paul D., MD   Guyton, John R., MD   Baccara-Dinet, Marie T., MD   Gipe, Daniel, MD Published in Journal of clinical lipidology (2014)
    “...Background Statin intolerance has been a major limitation in the use of statins, especially at higher doses. New effective treatments are needed for lowering...”
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  • 5
    Cover Image Journal Article
    Reminders and Recidivism: Using Administrative Data to Characterize Nonfilers and Conduct EITC Outreach
    by John Guyton   Pat Langetieg   Day Manoli   Mark Payne   Brenda Schafer   Michael Sebastiani Published in The American economic review (01.05.2017)
    “...This project uses third-party information reporting and population-level administrative tax data to identify the population of nonfilers. This population...”
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  • 6
    Cover Image Journal Article
    An assessment by the Statin Intolerance Panel: 2014 update
    by Guyton, John R., MD, FNLA   Bays, Harold E., MD, FNLA   Grundy, Scott M., MD, PhD, FNLA   Jacobson, Terry A., MD, FACP, FNLA Published in Journal of clinical lipidology (2014)
    “...Abstract This article from the National Lipid Association Statin Intolerance Panel provides a framework for understanding statin intolerance and makes general...”
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  • 7
    Cover Image Journal Article
    MR Spectroscopy of Cholesteryl Ester in Human Atherosclerosis
    by Guyton, John R., MD Published in JACC. Cardiovascular imaging (2013)
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  • 8
    Cover Image Journal Article
    ALIROCUMAB TREATMENT IN A REAL WORLD SETTING: SAFETY UPDATE FROM AN OPEN-LABEL TREATMENT EXTENSION TO THE ODYSSEY PROGRAM FOR PATIENTS WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEM...
    by Guyton, John R   Hovingh, G. Kees   Langslet, Gisle   Dufour, Robert   Baccara-Dinet, Marie   Din-Bell, Chantal   Manvelian, Garen   Farnier, Michel Published in Journal of the American College of Cardiology (2017)
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  • 9
    Cover Image Journal Article
    Usefulness of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) in Women to Lower Triglyceride Levels (Results from the MARINE and ANCHOR Trials)
    by Mosca, Lori, MD, MPH, PhD   Ballantyne, Christie M., MD   Bays, Harold E., MD   Guyton, John R., MD   Philip, Sephy, RPh, PharmD   Doyle, Ralph T., BA   Juliano, Rebecca A., PhD Published in The American journal of cardiology (2016)
    “...There are limited data on the efficacy and safety of triglyceride (TG)-lowering agents in women. We conducted subgroup analyses of the effects of icosapent...”
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  • 10
    Cover Image Journal Article
    What Works, What Doesn’t? Three Studies Designed to Improve Survey Response
    by Sun, Hanyu   Newsome, Jocelyn   McNulty, Jennifer   Levin, Kerry   Langetieg, Pat   Schafer, Brenda   Guyton, John Published in Field methods (01.08.2020)
    “...Over the past few decades, the survey industry has experienced a steady decline in response rates, which has posed numerous challenges for researchers, most...”
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  • 11
    Cover Image Journal Article
    Lipid-Altering Efficacy and Safety of Ezetimibe/Simvastatin Coadministered With Extended-Release Niacin in Patients With Type IIa or Type IIb Hyperlipidemia
    by Guyton, John R., MD   Brown, B. Greg, MD, PhD   Fazio, Sergio, MD, PhD   Polis, Adam, MA   Tomassini, Joanne E., PhD   Tershakovec, Andrew M., MD, MPH Published in Journal of the American College of Cardiology (2008)
    “...Lipid-Altering Efficacy and Safety of Ezetimibe/Simvastatin Coadministered With Extended-Release Niacin in Patients With Type IIa or Type IIb Hyperlipidemia...”
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  • 12
    Cover Image Journal Article
    ON-TREATMENT LDL-C LEVELS WHEN ALIROCUMAB DOSE IS DECREASED FROM 150 TO 75 MG EVERY 2 WEEKS IN PATIENTS WITH HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA: RESULTS FROM ODYSSEY OLE
    by Farnier, Michel   Guyton, John   Langslet, Gisle   Dufour, Robert   Baccara-Dinet, Marie   Din-Bell, Chantal   Manvelian, Garen   Hovingh, G. Kees Published in Journal of the American College of Cardiology (2017)
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  • 13
    Cover Image Journal Article
    ALIROCUMAB TITRATION STRATEGY ALLOWS INDIVIDUALIZED LDL-C REDUCTION IN A REAL WORLD SETTING: RESULTS FROM ODYSSEY OLE (LONG TERM COHORT)
    by Dufour, Robert   Hovingh, G. Kees   Guyton, John   Langslet, Gisle   Baccara-Dinet, Marie   Din-Bell, Chantal   Manvelian, Garen   Farnier, Michel Published in Journal of the American College of Cardiology (2017)
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  • 14
    Cover Image Journal Article
    Triglyceride-lowering therapies reduce cardiovascular disease event risk in subjects with hypertriglyceridemia
    by Maki, Kevin C., PhD, FNLA   Guyton, John R., MD, FNLA   Orringer, Carl E., MD, FNLA   Hamilton-Craig, Ian, MBBS, PhD   Alexander, Dominik D., PhD, MSPH   Davidson, Michael H., MD, FNLA Published in Journal of clinical lipidology (2016)
    “...Background Cardiovascular outcomes trials of fibrates, niacin, or omega-3 fatty acids alone, or added to a statin, have not consistently demonstrated reduced...”
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  • 15
    Cover Image Journal Article
    Safety Considerations with Gastrointestinally Active Lipid-Lowering Drugs
    by Jacobson, Terry A., MD   Armani, Annemarie, MD   McKenney, James M., PharmD   Guyton, John R., MD Published in The American journal of cardiology (2007)
    “...Gastrointestinally active agents such as cholesterol absorption inhibitors (CAIs) (eg, ezetimibe) and bile acid sequestrants (BAS) (the resins cholestyramine...”
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  • 16
    Cover Image Journal Article
    Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia and LDL-C of 160 mg/dl or Higher
    by Ginsberg, Henry N   Rader, Daniel J   Raal, Frederick J   Guyton, John R   Baccara-Dinet, Marie T   Lorenzato, Christelle   Pordy, Robert   Stroes, Erik Published in Cardiovascular drugs and therapy (2016)
    “...Even with statins and other lipid-lowering therapy (LLT), many patients with heterozygous familial hypercholesterolemia (heFH) continue to have elevated...”
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  • 17
    Cover Image Journal Article
    Long-Term Safety and Efficacy of Triple Combination Ezetimibe/Simvastatin Plus Extended-Release Niacin in Patients With Hyperlipidemia
    by Fazio, Sergio, MD, PhD   Guyton, John R., MD   Polis, Adam B., MA   Adewale, Adeniyi J., PhD   Tomassini, Joanne E., PhD   Ryan, Nicholas W., PharmD   Tershakovec, Andrew M., MD, MPH Published in The American journal of cardiology (2010)
    “...The safety and efficacy of combination ezetimibe/simvastatin (E/S) plus extended-release niacin was assessed in 942 patients with type IIa/IIb hyperlipidemia...”
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  • 18
    Cover Image Journal Article
    EFFICACY AND SAFETY OF DIFFERENT DOSING REGIMENS OF ALIROCUMAB (STARTING DOSES OF 75 MG EVERY TWO WEEKS AND 150 MG EVERY FOUR WEEKS) VERSUS PLACEBO IN PATIENTS WITH HYPERCHOLESTERO...
    by Stroes, Erik S.G   Guyton, John   Farnier, Michel   Lepor, Norman   Civeira, Fernando   Gaudet, Daniel   Watts, Gerald   Manvelian, Garen   Lecorps, Guillaume   Baccara-Dinet, Marie Published in Journal of the American College of Cardiology (17.03.2015)
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  • 19
    Cover Image Journal Article
    Pleiotropy and allelic heterogeneity in the TOMM40-APOE genomic region related to clinical and metabolic features of hepatitis C infection
    by Chiba-Falek, Ornit   Linnertz, Colton   Guyton, John   Gardner, Stephen D   Roses, Allen D   McCarthy, Jeanette J   Patel, Keyur Published in Human genetics (01.12.2012)
    “...Hepatitis C virus (HCV) modulates host lipid metabolism as part of its lifecycle and is dependent upon VLDL for co-assembly and secretion. HCV dyslipidemia is...”
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  • 20
    Cover Image Journal Article
    Review article: the impact of liver‐directed therapies on the atherogenic risk profile in non‐alcoholic steatohepatitis
    by Connelly, Margery A   Velez Rivera, Jonathan   Guyton, John R   Siddiqui, Mohammad Shadab   Sanyal, Arun J Published in Alimentary pharmacology & therapeutics (01.08.2020)
    “...Summary Background Patients with non‐alcoholic fatty liver disease (NAFLD), the most common cause of chronic liver disease, are at higher risk of...”
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