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Immunological investigations

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Immunological investigations [electronic resource]

Published in Immunological investigations

Journal Article

Overexpression of lncRNA HULC Attenuates Myocardial Ischemia/reperfusion Injury in Rat Models and Apoptosis of Hypoxia/reoxygenation Cardiomyocytes via Targeting miR-377-5p through...

by Liang, Huiqing Li, Fangjiang Li, Huixian Wang, Rui Du, Meiling Published in Immunological investigations (//)

“...Acute myocardial infarction (AMI) is characterized by myocardial tissue necrosis and activation of inflammatory response. This study aims to elucidate the...”

Journal Article

The Relationship of COX-2 Gene Polymorphisms and Susceptibility to Kawasaki Disease in Chinese Population

by Li, Shentang Shi, Ruting Tian, Lang Chen, Jia Li, Xin Huang, Lihua Yang, Zuocheng Published in Immunological investigations (17.02.2019)

“...Background: Kawasaki disease (KD) is an acute systemic vasculitis that predominantly affects children, and it can result in coronary artery lesions...”

Journal Article

Cancer/Testis Antigens: Expression, Regulation, Tumor Invasion, and Use in Immunotherapy of Cancers

by Salmaninejad, Arash Zamani, Mohammad Reza Pourvahedi, Mehrnaz Golchehre, Zahra Hosseini Bereshneh, Ali Rezaei, Nima Published in Immunological investigations (02.10.2016)

“...Cancer/testis antigens (CTAs) are named based on their expression pattern that is restricted in a number of normal and abnormal tissues. Tumor cells frequently...”

Journal Article

The role of cytokines in inflammatory bone loss

by Souza, Pedro P. C Lerner, Ulf H Published in Immunological investigations (01.10.2013)

“...Chronic inflammatory processes close to bone often lead to loss of bone in diseases such as rheumatoid arthritis, periodontitis, loosened joint prosthesis and...”

Journal Article

Circulating Levels of Osteoprotegerin, Osteocalcin and Osteopontin in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

by Liu, Li-Na Mao, Yan-Mei Zhao, Chan-Na Wang, Hong Yuan, Fei-Fei Li, Xiao-Mei Pan, Hai-Feng Published in Immunological investigations (17.02.2019)

“...Objective: Currently published data regarding the potential role of osteoprotegerin (OPG), osteocalcin (OCN) and osteopontin (OPN) for the discrimination...”

Journal Article

Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

by Raber, Patrick Ochoa, Augusto C Rodríguez, Paulo C Published in Immunological investigations (01.08.2012)

“...Patients with cancer have an impaired T cell response that can decrease the potential therapeutic benefit of cancer vaccines and other forms of immunotherapy...”

Journal Article

Interleukin-6 as a Predictor of the Risk of Cardiovascular Disease: A Meta-Analysis of Prospective Epidemiological Studies

by Zhang, Bo Li, Xiao-Ling Zhao, Cun-Rui Pan, Chen-Liang Zhang, Zheng Published in Immunological investigations (03.10.2018)

“...Objective: The etiology of cardiovascular disease (CVD) is complex owing to the interactions of genetic variance with environmental factors. Inflammatory...”

Journal Article

Short-Chain Fatty Acids Regulate Cytokines and Th17/Treg Cells in Human Peripheral Blood Mononuclear Cells in vitro

by Asarat, M Apostolopoulos, V Vasiljevic, T Donkor, O Published in Immunological investigations (02.04.2016)

“...Short-chain fatty acids (SCFAs) have been recognized as mediators of immune responses, including pathways of cytokine production. In this study, we...”

Journal Article

Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy

by Maccalli, Cristina Parmiani, Giorgio Ferrone, Soldano Published in Immunological investigations (03.04.2017)

“...Cancer-initiating cells (CICs) represent a relatively rare subpopulation of cells endowed with self-renewal, stemness properties, tumorigenicity in...”

Journal Article

MicroRNAs in the Diagnosis and Treatment of Cancer

by Mansoori, Behzad Mohammadi, Ali Shirjang, Solmaz Baradaran, Behzad Published in Immunological investigations (17.11.2017)

“...Immune cells are recruited into the tumor microenvironment and regulate anti- and pro-tumor signals. MicroRNAs (miRNAs) markedly control the immune system...”

Journal Article

Serum IL-6 and IL-8 Correlate with Prognostic Factors in Ovarian Cancer

by Sanguinete, Marcela Moisés Maluf Oliveira, Paula Honório De Martins-Filho, Agrimaldo Micheli, Douglas Côbo Tavares-Murta, Beatriz Martins Murta, Eddie Fernando Candido Nomelini, Rosekeila Simões Published in Immunological investigations (03.10.2017)

“...The aim of the study was to correlate serum levels of IL-2, IL-5, IL-6, IL-8, IL-10, and TNF-α with clinical, laboratory, and pathological prognostic factors...”

Journal Article

Dexamethasone Attenuates LPS-induced Acute Lung Injury through Inhibition of NF-κB, COX-2, and Pro-inflammatory Mediators

by Al-Harbi, Naif O Imam, Faisal Al-Harbi, Mohammed M Ansari, Mushtaq Ahmad Zoheir, Khairy M. A Korashy, Hesham M Sayed-Ahmed, Mohamed M Attia, Sabry M Shabanah, Othman A Ahmad, Sheikh Fayaz Published in Immunological investigations (18.05.2016)

“...Dexamethasone (DEX) is a synthetic glucocorticoid with potent anti-inflammatory effects that is widely used to treat inflammatory diseases. The aim of the...”

Journal Article

The Effect of Intravenous Selenium on Oxidative Stress in Critically Ill Patients with Acute Respiratory Distress Syndrome

by Mahmoodpoor, Ata Hamishehkar, Hadi Shadvar, Kamran Ostadi, Zohreh Sanaie, Sarvin Saghaleini, Seied Hadi Nader, Nader D Published in Immunological investigations (17.02.2019)

“...Objective: To modulate the inflammatory response in respiratory distress syndrome (ARDS) with selenium. Background: Selenium replenishes the glutathione...”

Journal Article

The Association of Interleukin-16 Gene Polymorphisms with IL-16 Serum Levels and Risk of Multiple Sclerosis

by Farrokhi, Mehrdad Masoudifar, Aria Derakhshan, Ali Saadatmand, Samira Rouhi-Boroujeni, Hojjat Etemadifar, Masoud Rezaei-Zarji, Saeid Javid, Ameneh Nobakht, Reza Deyhimi, Mitra Ekramnia, Afagh Ebrahimi, Milad Sheikh, Sajad Ansaripour, Sadra Amani-Beni, Ali Jahanbani-Ardakani, Hamidreza Published in Immunological investigations (02.02.2017)

“...Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS) that is immunologically...”

Journal Article

Upregulated IL-1 Receptor-associated Kinase 1 (IRAK1) in Systemic Lupus Erythematosus: IRAK1 Inhibition Represses Th17 Differentiation with Therapeutic Potential

by Zhou, Zhou Tian, Zhiqiang Zhang, Mengjie Zhang, Yuxun Ni, Bing Hao, Fei Published in Immunological investigations (04.07.2018)

“...Systemic lupus erythematosus (SLE) is a typical autoimmune disease. Genome-wide analyses have revealed that interleukin-1 receptor-associated kinase 1 (IRAK1)...”

Journal Article

Effect of Class Switch Recombination Defect on the Phenotype of Ataxia-Telangiectasia Patients

by Amirifar, Parisa Mozdarani, Hossein Yazdani, Reza Kiaei, Fatemeh Moeini Shad, Tannaz Shahkarami, Sepideh Abolhassani, Hassan Delavari, Samaneh Sohani, Mahsa Rezaei, Arezou Hassanpour, Gholamreza Akrami, Seyed Mohammad Aghamohammadi, Asghar Published in Immunological investigations (17.02.2021)

“...Objectives: Ataxia-telangiectasia (A-T) is an autosomal recessive neurodegenerative disorder with multisystem involvement caused by homozygous or compound...”

Journal Article

by Li, Na Fan, Xiude Wang, Xiaoyun Deng, Huan Zhang, Kun Zhang, Xiaoge Han, Qunying Lv, Yi Liu, Zhengwen Published in Immunological investigations (19.05.2019)

“...Background: Despite the identification of autophagy-related protein 5 (ATG5) as a molecule involved in the activated autophagy machinery during hepatitis B...”

Journal Article

Disequilibrium of M1 and M2 Macrophages Correlates with the Development of Experimental Inflammatory Bowel Diseases

by Zhu, Wei Yu, Jianbo Nie, Ying Shi, XueKui Liu, Yang Li, Fujuan Zhang, Xiao-li Published in Immunological investigations (01.10.2014)

“...Ulcerative colitis, a major inflammatory bowel disease, is an idiopathic inflammatory disorder of the colonic mucosa, accompanied by an aberrant immune...”

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