Search Results - "Laforest, Richard"

Journal Article

Reply to 'Is Cherenkov luminescence bright enough for photodynamic therapy?'

by Kotagiri, Nalinikanth Laforest, Richard Achilefu, Samuel Published in Nature nanotechnology (01.05.2018)

Journal Article

NON-CONVENTIONAL PET NUCLIDES: PRODUCTION AND IMAGING

by Laforest, Richard Published in Momento (01.07.2015)

“...Medical cyclotrons are now commonly used for the production of PET nuclides by the (pn) reaction. These devices are typically capable of delivering 10-15 MeV...”

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Journal Article

Cavitation dose painting for focused ultrasound-induced blood-brain barrier disruption

by Yang, Yaoheng Zhang, Xiaohui Ye, Dezhuang Laforest, Richard Williamson, Jeffrey Liu, Yongjian Chen, Hong Published in Scientific reports (26.02.2019)

“...Focused ultrasound combined with microbubble for blood-brain barrier disruption (FUS-BBBD) is a promising technique for noninvasive and localized brain drug...”

Journal Article

Evaluation of diagnostic performance of whole-body simultaneous PET/MRI in pediatric lymphoma

by Ponisio, Maria Rosana McConathy, Jonathan Laforest, Richard Khanna, Geetika Published in Pediatric radiology (01.08.2016)

“...Whole-body 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is the standard of care for lymphoma. Simultaneous PET/MRI...”

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2031-P: Obesity and Insulin Resistance Alter the Biodistribution of Whole Body Insulin-Stimulated Glucose Disposal

by KOH, HAN-CHOW VLIET, STEPHAN VAN LAFOREST, RICHARD GROPLER, ROBERT KLEIN, SAMUEL MITTENDORFER, BETTINA Published in Diabetes (New York, N.Y.) (01.06.2020)

“...Insulin-stimulated whole-body (WB) glucose disposal (GD) is thought to occur predominately in skeletal muscle (SM). Studies in animals suggest adipose tissue...”

Journal Article

Diels-Alder Reaction for Tumor Pretargeting: In Vivo Chemistry Can Boost Tumor Radiation Dose Compared with Directly Labeled Antibody

by Rossin, Raffaella Läppchen, Tilman van den Bosch, Sandra M Laforest, Richard Robillard, Marc S Published in The Journal of nuclear medicine (1978) (01.11.2013)

“...Current pretargeting systems use noncovalent biologic interactions, which are prone to immunogenicity. We previously developed a novel approach based on the...”

Journal Article

Heterogeneity in insulin-stimulated glucose uptake among different muscle groups in healthy lean people and people with obesity

by Koh, Han-Chow E van Vliet, Stephan Meyer, Gretchen A Laforest, Richard Gropler, Robert J Klein, Samuel Mittendorfer, Bettina Published in Diabetologia (01.05.2021)

“...It has been proposed that muscle fibre type composition and perfusion are key determinants of insulin-stimulated muscle glucose uptake, and alterations in...”

Journal Article

Fluselenamyl: Evaluation of radiation dosimetry in mice and pharmacokinetics in brains of non-human primate

by Sundaram, G.S.M Jones, Lynne Zhou, Yun Laforest, Richard Sharma, Vijay Published in Nuclear medicine and biology (01.03.2020)

“...To allow quantitative assessment of therapeutic efficacy for therapeutic interventions (either approved or undergoing FDA approvals) for either inhibiting or...”

Journal Article

Deep learning‐based T1‐enhanced selection of linear attenuation coefficients (DL‐TESLA) for PET/MR attenuation correction in dementia neuroimaging

by Chen, Yasheng Ying, Chunwei Binkley, Michael M Juttukonda, Meher R Flores, Shaney Laforest, Richard Benzinger, Tammie L. S An, Hongyu Published in Magnetic resonance in medicine (01.07.2021)

“...Purpose The accuracy of existing PET/MR attenuation correction (AC) has been limited by a lack of correlation between MR signal and tissue electron density...”

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NEMA NU 4-2008 comparison of preclinical PET imaging systems

by Goertzen, Andrew L Bao, Qinan Bergeron, Mélanie Blankemeyer, Eric Blinder, Stephan Cañadas, Mario Chatziioannou, Arion F Dinelle, Katherine Elhami, Esmat Jans, Hans-Sonke Lage, Eduardo Lecomte, Roger Sossi, Vesna Surti, Suleman Tai, Yuan-Chuan Vaquero, Juan José Vicente, Esther Williams, Darin A Laforest, Richard Published in The Journal of nuclear medicine (1978) (01.08.2012)

“...The National Electrical Manufacturers Association (NEMA) standard NU 4-2008 for performance measurements of small-animal tomographs was recently published...”

Journal Article

Obesity Is Associated With Increased Basal and Postprandial β-Cell Insulin Secretion Even in the Absence of Insulin Resistance

by van Vliet, Stephan Koh, Han-Chow E Patterson, Bruce W Yoshino, Mihoko LaForest, Richard Gropler, Robert J Klein, Samuel Mittendorfer, Bettina Published in Diabetes (New York, N.Y.) (01.10.2020)

“...We tested the hypothesis that obesity, independent of insulin resistance, is associated with increased insulin secretion. We compared insulin kinetics before...”

Journal Article

Evaluation of [89Zr]trastuzumab-PET/CT in differentiating HER2-positive from HER2-negative breast cancer

by Dehdashti, Farrokh Wu, Ningying Bose, Ron Naughton, Michael J Ma, Cynthia X Marquez-Nostra, Bernadette V Diebolder, Philipp Mpoy, Cedric Rogers, Buck E Lapi, Suzanne E Laforest, Richard Siegel, Barry A Published in Breast cancer research and treatment (01.06.2018)

“...To evaluate whether tumor uptake of [89Zr]trastuzumab can distinguish HER2-positive from HER2-negative breast cancer.Women with HER2-positive (n = 34) and...”

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Journal Article

[89Zr]Trastuzumab: Evaluation of Radiation Dosimetry, Safety, and Optimal Imaging Parameters in Women with HER2-Positive Breast Cancer

by Laforest, Richard Lapi, Suzanne E Oyama, Reiko Bose, Ron Tabchy, Adel Marquez-Nostra, Bernadette V Burkemper, Jennifer Wright, Brian D Frye, Jennifer Frye, Sarah Siegel, Barry A Dehdashti, Farrokh Published in Molecular imaging and biology (01.12.2016)

“...The purpose of the present study is to evaluate safety, human radiation dosimetry, and optimal imaging time of [89Zr]trastuzumab in patients with HER2-positive...”

Journal Article

Acute Rodent Tolerability, Toxicity, and Radiation Dosimetry Estimates of the S1P1-Specific Radioligand [ 11 C]CS1P1

by Liu, Hui Laforest, Richard Gu, Jiwei Luo, Zonghua Jones, Lynne A Gropler, Robert J Benzinger, Tammie L S Tu, Zhude Published in Molecular imaging and biology (01.04.2020)

“...In preclinical studies with rodent models of inflammatory diseases, [ C]CS1P1 has been identified as a promising imaging agent targeting...”

Journal Article

PET/MRI of Hepatic 90Y Microsphere Deposition Determines Individual Tumor Response

by Fowler, Kathryn J Fowler, Kathryn J Maughan, Nichole M Maughan, Nichole M Laforest, Richard Laforest, Richard Saad, Nael E Saad, Nael E Sharma, Akash Sharma, Akash Olsen, Jeffrey Olsen, Jeffrey Speirs, Christina K Speirs, Christina K Parikh, Parag J Parikh, Parag J Published in Cardiovascular and interventional radiology (01.06.2016)

“...The purpose of our study is to determine if there is a relationship between dose deposition measured by PET/MRI and individual lesion response to yttrium-90...”

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Journal Article

In vivo assessment of tumor hypoxia in lung cancer with 60Cu-ATSM

by Dehdashti, Farrokh Mintun, Mark A Lewis, Jason S Bradley, Jeffrey Govindan, Ramaswamy Laforest, Richard Welch, Michael J Siegel, Barry A Published in European journal of nuclear medicine and molecular imaging (01.06.2003)

“...Tumor hypoxia is recognized as an important determinant of response to therapy. In this study we investigated the feasibility of clinical imaging with...”

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Journal Article

Chemokine Receptor 2-targeted Molecular Imaging in Pulmonary Fibrosis. A Clinical Trial

by Brody, Steven L Gunsten, Sean P Luehmann, Hannah P Sultan, Debbie H Hoelscher, Michelle Heo, Gyu Seong Pan, Jiehong Koenitzer, Jeffrey R Lee, Ethan C Huang, Tao Mpoy, Cedric Guo, Shuchi Laforest, Richard Salter, Amber Russell, Tonya D Shifren, Adrian Combadiere, Christophe Lavine, Kory J Kreisel, Daniel Humphreys, Benjamin D Rogers, Buck E Gierada, David S Byers, Derek E Gropler, Robert J Chen, Delphine L Atkinson, Jeffrey J Liu, Yongjian Published in American journal of respiratory and critical care medicine (01.01.2021)

“...Idiopathic pulmonary fibrosis (IPF) is a progressive inflammatory lung disease without effective molecular markers of disease activity or treatment responses...”

Journal Article

Fluselenamyl: A novel benzoselenazole derivative for PET detection of amyloid plaques (Aβ) in Alzheimer’s disease

by Sundaram, G S M Dhavale, Dhruva D Prior, Julie L Yan, Ping Cirrito, John Rath, Nigam P Laforest, Richard Cairns, Nigel J Lee, Jin-Moo Kotzbauer, Paul T Sharma, Vijay Published in Scientific reports (02.11.2016)

“...Fluselenamyl (5), a novel planar benzoselenazole shows traits desirable of enabling noninvasive imaging of Aβ pathophysiology in vivo; labeling of both diffuse...”

Journal Article

Impact of MR-based attenuation correction on neurologic PET studies

by Su, Yi Rubin, Brian B McConathy, Jonathan Laforest, Richard Qi, Jing Sharma, Akash Priatna, Agus Benzinger, Tammie L S Published in The Journal of nuclear medicine (1978) (01.06.2016)

“...Hybrid PET and MR scanners have become a reality in recent years, with the benefits of reduced radiation exposure, reduction of imaging time, and potential...”

Journal Article

Ex Vivo and In Vivo Evaluation of Overexpressed VLA-4 in Multiple Myeloma Using LLP2A Imaging Agents

by Soodgupta, Deepti Zhou, Haiying Beaino, Wissam Lu, Lan Rettig, Michael Snee, Mark Skeath, James DiPersio, John F Akers, Walter J Laforest, Richard Anderson, Carolyn J Tomasson, Michael H Shokeen, Monica Published in The Journal of nuclear medicine (1978) (01.04.2016)

“...Very-late-antigen-4 (VLA-4, α4β1 integrin, CD49d/CD29) is a transmembrane adhesion receptor that plays an important role in cancer and immune responses...”

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