Search Results - "Marek, Stefanie"

Journal Article

ECMO and Cytokine Removal for Bridging to Surgery in a Patient with Ischemic Ventricular Septal Defect – a Case Report

by Marek, Stefanie Gamper, Gunnar Reining, Georg Bergmann, Peter Mayr, Harald Kliegel, Andreas Published in International journal of artificial organs (01.09.2017)

“...Even in the modern era of percutaneous coronary intervention, postinfarction ventricular septal defect (VSD) remains a serious and often lethal complication...”

Journal Article

Minimal Invasive Pericardial Perfusion Model in Swine: A Translational Model for Cardiac Remodeling After Ischemia/Reperfusion Injury

by Marek-Iannucci, Stefanie Thomas, Amandine Gottlieb, Roberta A Published in Frontiers in physiology (2020-00-00)

“...Adverse remodeling leads to heart failure after myocardial infarction (MI), with important impact on morbidity and mortality. New therapeutic approaches are...”

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Journal Article

Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury

by Marek-Iannucci, Stefanie Thomas, Amandine Hou, Jean Crupi, Annunziata Sin, Jon Taylor, David J Czer, Lawrence S Esmailian, Fardad Mentzer, Jr, Robert M Andres, Allen M Gottlieb, Roberta A Published in Scientific reports (10.07.2019)

“...Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocardial function, yet exact mechanisms remain unclear. Impaired autophagy...”

Journal Article

Decrease of Cardiac Parkin Protein in Obese Mice

by Thomas, Amandine Marek-Iannucci, Stefanie Tucker, Kyle C Andres, Allen M Gottlieb, Roberta A Published in Frontiers in cardiovascular medicine (2019-00-00)

“...Mitophagy plays a major role in heart physiology. Impairment of Parkin-dependent mitophagy in heart is known to be deleterious. Obesity is a known...”

Journal Article

Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation

by Dagvadorj, Jargalsaikhan Mikulska-Ruminska, Karolina Tumurkhuu, Gantsetseg Ratsimandresy, Rojo A Carriere, Jessica Andres, Allen M Marek-Iannucci, Stefanie Song, Yang Chen, Shuang Lane, Malcolm Dorfleutner, Andrea Gottlieb, Roberta A Stehlik, Christian Cassel, Suzanne Sutterwala, Fayyaz S Bahar, Ivet Crother, Timothy R Arditi, Moshe Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2021)

“...The balance between NLRP3 inflammasome activation and mitophagy is essential for homeostasis and cellular health, but this relationship remains poorly...”

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Journal Article

Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression

by Kumar, Ashutosh Lewin, Astrid Rani, Pittu Sandhya Qureshi, Insaf A Devi, Savita Majid, Mohammad Kamal, Elisabeth Marek, Stefanie Hasnain, Seyed E Ahmed, Niyaz Published in Cytokine (Philadelphia, Pa.) (01.10.2013)

“...•M. tuberculosis dormancy protein, DATIN participates in innate functions.•DATIN was shown to interact with TLR2 and upregulated proinflammatory cytokines.•The...”

Journal Article

Hypothermic Regulation Of Cardiac Mitochondrial Dynamics

by Taylor, David Germano, Juliana Marek-Iannucci, Stefanie Hadj-Moussa, Hanane Storey, Kenneth Gottlieb, Roberta Published in Cryobiology (01.12.2019)

Journal Article

Hypothermia promotes mitochondrial elongation In cardiac cells via inhibition of Drp1

by Taylor, David Germano, Juliana Song, Yang Hadj-Moussa, Hanane Marek-Iannucci, Stefanie Dhanji, Raeesa Sin, Jon Czer, Lawrence S.C Storey, Kenneth B Gottlieb, Roberta A Published in Cryobiology (01.10.2021)

“...Hypothermia is a valuable clinical tool in mitigating against the consequences of ischemia in surgery, stroke, cardiac arrest and organ preservation...”

Publication

Giardia duodenalis arginine deiminase and its role in host-parasite interplay

by Marek, Stefanie
01.01.2014

“...Infektionen mit dem intestinalen Parasiten Giardia duodenalis, verursachen weltweit eine der häufigsten humanen Parasitosen. Bislang konnten keine eindeutigen...”

Journal Article

Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis

by Piplani, Honit Marek-Iannucci, Stefanie Sin, Jon Hou, Jean Takahashi, Toshimasa Sharma, Ankush de Freitas Germano, Juliana Waldron, Richard T Saadaeijahromi, Hannaneh Song, Yang Gulla, Aiste Wu, Bechien Lugea, Aurelia Andres, Allen M Gaisano, Herbert Y Gottlieb, Roberta A Pandol, Stephen J Published in Biochimica et biophysica acta. Molecular basis of disease (01.11.2019)

“...During pancreatitis, autophagy is activated, but lysosomal degradation of dysfunctional organelles including mitochondria is impaired, resulting in acinar cell...”

Journal Article

Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis

Published in JCI insight (22.09.2021)

Dissertation

Giardia duodenalis arginine deiminase and its role in host-parasite interplay

by Marek, Stefanie

“...Infektionen mit dem intestinalen Parasiten Giardia duodenalis, verursachen weltweit eine der häufigsten humanen Parasitosen. Bislang konnten keine eindeutigen...”

Journal Article

Abstract 16892: Cold Exposure Induces Drp1-Mediated Mitochondrial Elongation in Cardiomyocytes and is Associated With Sustained Respiratory Suppression

by Taylor, David Marek-Iannucci, Stefanie Gottlieb, Roberta A Published in Circulation (New York, N.Y.) (06.11.2018)

“...IntroductionThe effects of cold exposure on the heart are poorly understood. Cardiac hypothermia arises exclusively in the context of coincident ischemia,...”

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Journal Article

Abstract 12638: Autophagy-mitophagy Induction Improves Cardiovascular Inflammation in a Murine Model of Kawasaki Disease Vasculitis

by Marek-iannucci, Stefanie Gomez, Angela Moreira, Debbie Lane, Malcolm Porritt, Rebecca Lee, Youngho Shimada, Kenichi Crother, Timothy R Noval Rivas, Magali Arditi, Moshe Published in Circulation (New York, N.Y.) (17.11.2020)

“...Kawasaki Disease (KD), an acute febrile illness and systemic vasculitis of unknown etiology, is the leading cause of acquired heart disease among children...”

Journal Article

Recruitment of pro-IL-1[alpha] to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation

“...The balance between NLRP3 inflammasome activation and mitophagy is essential for homeostasis and cellular health, but this relationship remains poorly...”

Web Resource

Giardia duodenalis arginine deiminase and its role in host-parasite interplay

by Marek, Stefanie

“...Provider: Deutsche Digitale Bibliothek - Institution: Deutsche Nationalbibliothek - Data provided by Europeana Collections- Berlin, Humboldt Universität zu...”

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Journal Article

Decrease of Cardiac Parkin Protein in Obese Mice

by Thomas, Amandine Marek-Iannucci, Stefanie Tucker, Kyle C Andres, Allen M Gottlieb, Roberta A Published in Frontiers in Cardiovascular Medicine (01.01.2020)

“...Mitophagy plays a major role in heart physiology. Impairment of Parkin-dependent mitophagy in heart is known to be deleterious. Obesity is a known...”

Publication

Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression

by Kumar, Ashutosh Lewin, Astrid Rani, Pittu Sandhya Qureshi, Insaf A Devi, Savita Majid, Mohammad Kamal, Elisabeth Marek, Stefanie Hasnain, Seyed E Ahmed, Niyaz
29.06.2013

“...Mycobacterium tuberculosis, the cause of tuberculosis in humans, is present approximately in one third of the world’s population, mostly in a dormant state...”

Journal Article

Dormancy Associated Translation Inhibitor (DATIN/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression

“...Mycobacterium tuberculosis, the cause of tuberculosis in humans, is present approximately in one third of the world’s population, mostly in a dormant state...”

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