Search Results - "Mismatch"

Journal Article

Insights from a decade of biophysical studies on MutL: Roles in strand discrimination and mismatch removal

by Guarné, Alba Charbonnier, Jean-Baptiste Published in Progress in biophysics and molecular biology (01.03.2015)

“...DNA mismatch repair (MMR) is a conserved pathway that safeguards genome integrity by correcting replication errors. The coordinated actions of two proteins...”

Journal Article

β Clamp Directs Localization of Mismatch Repair in Bacillus subtilis

by Simmons, Lyle A Davies, Bryan W Grossman, Alan D Walker, Graham C Published in Molecular cell (2008)

“...MutS homologs function in several cellular pathways including mismatch repair (MMR), the process by which mismatches introduced during DNA replication are...”

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Journal Article

Importance of base-pair opening for mismatch recognition

by Bouchal, Tomáš Durník, Ivo Illík, Viktor Réblová, Kamila Kulhánek, Petr Published in Nucleic acids research (18.11.2020)

“...Mismatch repair is a highly conserved cellular pathway responsible for repairing mismatched dsDNA. Errors are detected by the MutS enzyme, which most likely...”

Journal Article

Balancing repair and tolerance of DNA damage caused by alkylating agents

by Fu, Dragony Calvo, Jennifer A Samson, Leona D Published in Nature reviews. Cancer (12.01.2012)

“...Alkylating agents constitute a major class of frontline chemotherapeutic drugs that inflict cytotoxic DNA damage as their main mode of action, in addition to...”

Journal Article

Conservation, mismatch and the research-implementation gap

by Jarvis, R. M Borrelle, S. B Breen, B. Bollard Towns, D. R Published in Pacific conservation biology (2015-00-00)

“...Despite calls to better link research and practice, the gap between knowing and doing continues to limit conservation success. Here we report on the outcomes...”

Journal Article

ATP Alters the Diffusion Mechanics of MutS on Mismatched DNA

by Cho, Won-Ki Jeong, Cherlhyun Kim, Daehyung Chang, Minhyeok Song, Kyung-Mi Hanne, Jeungphill Ban, Changill Fishel, Richard Lee, Jong-Bong Published in Structure (London) (03.07.2012)

“...The mismatch repair (MMR) initiation protein MutS forms at least two types of sliding clamps on DNA: a transient mismatch searching clamp (∼1 s) and an...”

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Journal Article

Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops

by Gupta, Shikha Gellert, Martin Yang, Wei Published in Nature structural & molecular biology (18.12.2011)

“...DNA mismatch repair corrects replication errors, thus reducing mutation rates and microsatellite instability. Genetic defects in this pathway cause Lynch...”

Journal Article

Mismatch unemployment

by Sahin, Aysegül Song, Joseph Topa, Giorgio Violante, Giovanni L Published in The American economic review (2014)

“...We develop a framework where mismatch between vacancies and job seekers across sectors translates into higher unemployment by lowering the aggregate...”

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Journal Article

Mechanism of formation of a toroid around DNA by the mismatch sensor protein

by Nirwal, Shivlee Kulkarni, Dhananjaya S Sharma, Amit Rao, Desirazu N Nair, Deepak T Published in Nucleic acids research (09.01.2018)

“...Abstract The DNA mismatch repair (MMR) pathway removes errors that appear during genome replication. MutS is the primary mismatch sensor and forms an...”

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Journal Article

Design of frequency-interleaved ADC with mismatch compensation

by Qiu, L Zheng, Y.J Siek, L Published in Electronics letters (24.04.2014)

“...A frequency-interleaving-based multichannel analogue-to-digitial converter (ADC) with mismatch compensation is presented, which is immune from the time skew...”

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Journal Article

Postreplicative mismatch repair

by Jiricny, Josef Published in Cold Spring Harbor perspectives in biology (01.04.2013)

“...The mismatch repair (MMR) system detects non-Watson-Crick base pairs and strand misalignments arising during DNA replication and mediates their removal by...”

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