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1by Holgado, Alejo J Nevado Terry, John R Bogacz, Rafal Published in The Journal of neuroscience (15.09.2010)“...The advance of Parkinson's disease is associated with the existence of abnormal oscillations within the basal ganglia with frequencies in the beta band (13-30...”
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2by Nevado‐Holgado, Alejo J Mallet, Nicolas Magill, Peter J Bogacz, Rafal Published in The Journal of physiology (01.04.2014)“...Key points The firing of subthalamic nucleus (STN) neurons and two types of external globus pallidus (GP) neuron becomes excessively and rhythmically...”
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3by Winchester, Laura M Powell, John Lovestone, Simon Nevado-Holgado, Alejo J Published in Genome medicine (28.06.2018)“...Studies have shown that low haemoglobin and anaemia are associated with poor cognition, and anaemia is known to be associated with Alzheimer's disease (AD),...”
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4by Westwood, Sarah Liu, Benjamine Baird, Alison L Anand, Sneha Nevado-Holgado, Alejo J Newby, Danielle Pikkarainen, Maria Hallikainen, Merja Kuusisto, Johanna Streffer, Johannes R Novak, Gerald Blennow, Kaj Andreasson, Ulf Zetterberg, Henrik Smith, Ulf Laakso, Markku Soininen, Hilkka Lovestone, Simon Published in Alzheimer's research & therapy (26.04.2017)“...Insulin resistance (IR) has previously been associated with an increased risk of developing Alzheimer's disease (AD), although the relationship between IR and...”
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5by Rojo, Ana I Pajares, Marta Rada, Patricia Nuñez, Angel Nevado-Holgado, Alejo J Killik, Richard Van Leuven, Fred Ribe, Elena Lovestone, Simon Yamamoto, Masayuki Cuadrado, Antonio Published in Redox biology (01.10.2017)“...Failure to translate successful neuroprotective preclinical data to a clinical setting in Alzheimer's disease (AD) indicates that amyloidopathy and tauopathy...”
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6by Nevado-Holgado, Alejo J Marten, Frank Richardson, Mark P Terry, John R Published in NeuroImage (Orlando, Fla.) (01.02.2012)“...In this paper we propose that the dynamic evolution of EEG activity during epileptic seizures may be characterised as a path through parameter space of a...”
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8by Cullen, Breda Newby, Danielle Lee, Duncan Lyall, Donald M Nevado-Holgado, Alejo J Evans, Jonathan J Pell, Jill P Lovestone, Simon Cavanagh, Jonathan Published in Scientific reports (14.08.2018)“...Observational studies have shown consistently increased likelihood of dementia or mild cognitive impairment diagnoses in people with higher air pollution...”
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10by Nevado-Holgado, Alejo J Kim, Chi-Hun Winchester, Laura Gallacher, John Lovestone, Simon Published in BMJ open (01.11.2016)“...ObjectiveTo investigate medications associated with cognitive function.DesignPopulation-based cross-sectional cohort study.SettingUK Biobank.ParticipantsUK...”
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11by Nevado-Holgado, Alejo J Lovestone, Simon Published in Computational and structural biotechnology journal (2017)“...Alzheimer's disease (AD) represents a substantial unmet need, due to increasing prevalence in an ageing society and the absence of a disease modifying therapy...”
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13by Perera, Gayan Gungabissoon, Usha Alexander, Myriam Ansel, David Avillach, Paul Salles, Talita Duarte Gordon, Mark Forrest Nevado-Holgado, Alejo J Novak, Gerald P Pasqua, Alessandro Pedersen, Lars Ponjoan, Anna Rijnbeek, Peter Van Der Lei, Johan Stewart, Robert Published in Alzheimer's & dementia (01.07.2017)
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14by Ashton, Nicholas J Nevado-Holgado, Alejo J Lynham, Steven Ward, Malcolm Gupta, Veer Bala Chatterjee, Pratishtha Gooze, Kathryn Hone, Eugene Pedrini, Steve Bush, Ashley I Rowe, Christopher C Villemagne, Victor L.L Ames, David Masters, Colin L Aarsland, Dag Lovestone, Simon Martins, Ralph N Hye, Abdul Published in Alzheimer's & dementia (01.07.2017)
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15by Newby, Danielle Prieto-Alhambra, Daniel Duarte-Salles, Talita Ansell, David Pedersen, Lars van der Lei, Johan Mosseveld, Mees Rijnbeek, Peter James, Glen Alexander, Myriam Egger, Peter Podhorna, Jana Stewart, Robert Perera, Gayan Avillach, Paul Grosdidier, Solène Lovestone, Simon Nevado-Holgado, Alejo J Published in Alzheimer's research & therapy (06.04.2020)“...Inflammatory processes have been shown to play a role in dementia. To understand this role, we selected two anti-inflammatory drugs (methotrexate and...”
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16by Westwood, Sarah Baird, Alison L Hye, Abdul Ashton, Nicholas J Nevado-Holgado, Alejo J Anand, Sneha N Liu, Benjamine Newby, Danielle Bazenet, Chantal Kiddle, Steven J Ward, Malcolm Newton, Ben Desai, Keyur Tan Hehir, Cristina Zanette, Michelle Galimberti, Daniela Parnetti, Lucilla Lleó, Alberto Baker, Susan Narayan, Vaibhav A van der Flier, Wiesje M Scheltens, Philip Teunissen, Charlotte E Visser, Pieter Jelle Lovestone, Simon Published in Frontiers in aging neuroscience (2018)“...Background: Blood biomarkers may aid in recruitment to clinical trials of Alzheimer's disease (AD) modifying therapeutics by triaging potential trials...”
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17by Nevado-Holgado, Alejo J Ribe, Elena Thei, Laura Furlong, Laura Mayer, Miguel-Angel Quan, Jie Richardson, Jill C Cavanagh, Jonathan Consortium, Nima Lovestone, Simon Published in Cells (Basel, Switzerland) (08.05.2019)“...As genome-wide association studies (GWAS) have grown in size, the number of genetic variants that have been associated per disease has correspondingly...”
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18by Yu, Rongqin Nevado-Holgado, Alejo J Molero, Yasmina D'Onofrio, Brian M Larsson, Henrik Howard, Louise M Fazel, Seena Moyer, Caitlin“...Using Swedish nationwide registries, we identified men from 9 diagnostic groups over 1998-2013, with sample sizes ranging from 9,529 with autism to 88,182 with...”
edited by Hay, Phillipa J
Published in PLoS medicine (17.12.2019)
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19by Donnelly, Nicholas A Holtzman, Tahl Rich, P Dylan Nevado-Holgado, Alejo J Fernando, Anushka B P Van Dijck, Gert Holzhammer, Tobias Paul, Oliver Ruther, Patrick Paulsen, Ole Robbins, Trevor W Dalley, Jeffrey W“...Actions expressed prematurely without regard for their consequences are considered impulsive. Such behaviour is governed by a network of brain regions...”
edited by Tort, Adriano B. L
Published in PloS one (2014-00-00)
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20by Winchester, Laura Shi, Liu Kormilitzin, Andrey Nevado‐Holgado, Alejo J Published in Alzheimer's & dementia (01.12.2020)“...Background Development of reproducible blood‐based protein biomarker for Alzheimer’s Disease would allow clinicians and researchers to diagnose and potentially...”