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  • Your search results: "Nevado-Holgado, Alejo J"
Showing 1 - 20 results of 96 for search '"Nevado-Holgado, Alejo J"', query time: 1.90s Narrow search
  • 1
    Cover Image Journal Article
    Conditions for the Generation of Beta Oscillations in the Subthalamic Nucleus-Globus Pallidus Network
    by Holgado, Alejo J Nevado   Terry, John R   Bogacz, Rafal Published in The Journal of neuroscience (15.09.2010)
    “...The advance of Parkinson's disease is associated with the existence of abnormal oscillations within the basal ganglia with frequencies in the beta band (13-30...”
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  • 2
    Cover Image Journal Article
    Effective connectivity of the subthalamic nucleus–globus pallidus network during Parkinsonian oscillations
    by Nevado‐Holgado, Alejo J   Mallet, Nicolas   Magill, Peter J   Bogacz, Rafal Published in The Journal of physiology (01.04.2014)
    “...Key points The firing of subthalamic nucleus (STN) neurons and two types of external globus pallidus (GP) neuron becomes excessively and rhythmically...”
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  • 3
    Cover Image Journal Article
    Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer’s disease
    by Winchester, Laura M   Powell, John   Lovestone, Simon   Nevado-Holgado, Alejo J Published in Genome medicine (28.06.2018)
    “...Studies have shown that low haemoglobin and anaemia are associated with poor cognition, and anaemia is known to be associated with Alzheimer's disease (AD),...”
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  • 4
    Cover Image Journal Article
    The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer’s pathology
    by Westwood, Sarah   Liu, Benjamine   Baird, Alison L   Anand, Sneha   Nevado-Holgado, Alejo J   Newby, Danielle   Pikkarainen, Maria   Hallikainen, Merja   Kuusisto, Johanna   Streffer, Johannes R   Novak, Gerald   Blennow, Kaj   Andreasson, Ulf   Zetterberg, Henrik   Smith, Ulf   Laakso, Markku   Soininen, Hilkka   Lovestone, Simon Published in Alzheimer's research & therapy (26.04.2017)
    “...Insulin resistance (IR) has previously been associated with an increased risk of developing Alzheimer's disease (AD), although the relationship between IR and...”
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  • 5
    Cover Image Journal Article
    NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology
    by Rojo, Ana I   Pajares, Marta   Rada, Patricia   Nuñez, Angel   Nevado-Holgado, Alejo J   Killik, Richard   Van Leuven, Fred   Ribe, Elena   Lovestone, Simon   Yamamoto, Masayuki   Cuadrado, Antonio Published in Redox biology (01.10.2017)
    “...Failure to translate successful neuroprotective preclinical data to a clinical setting in Alzheimer's disease (AD) indicates that amyloidopathy and tauopathy...”
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  • 6
    Cover Image Journal Article
    Characterising the dynamics of EEG waveforms as the path through parameter space of a neural mass model: Application to epilepsy seizure evolution
    by Nevado-Holgado, Alejo J   Marten, Frank   Richardson, Mark P   Terry, John R Published in NeuroImage (Orlando, Fla.) (01.02.2012)
    “...In this paper we propose that the dynamic evolution of EEG activity during epileptic seizures may be characterised as a path through parameter space of a...”
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  • 7
    Cover Image Journal Article
    EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE
    by Winchester, Laura   Nevado-Holgado, Alejo J   Lovestone, Simon Published in Alzheimer's & dementia (01.07.2017)
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  • 8
    Cover Image Journal Article
    Cross-sectional and longitudinal analyses of outdoor air pollution exposure and cognitive function in UK Biobank
    by Cullen, Breda   Newby, Danielle   Lee, Duncan   Lyall, Donald M   Nevado-Holgado, Alejo J   Evans, Jonathan J   Pell, Jill P   Lovestone, Simon   Cavanagh, Jonathan Published in Scientific reports (14.08.2018)
    “...Observational studies have shown consistently increased likelihood of dementia or mild cognitive impairment diagnoses in people with higher air pollution...”
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  • 9
    Cover Image Journal Article
    A PARKINSON’S DISEASE PROTEIN BIOMARKER PANEL USING THE SOMAMER ASSAY AND MACHINE LEARNING
    by Barber, Imelda S   Nevado-Holgado, Alejo J   Lovestone, Simon Published in Alzheimer's & dementia (01.07.2017)
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  • 10
    Cover Image Journal Article
    Commonly prescribed drugs associate with cognitive function: a cross-sectional study in UK Biobank
    by Nevado-Holgado, Alejo J   Kim, Chi-Hun   Winchester, Laura   Gallacher, John   Lovestone, Simon Published in BMJ open (01.11.2016)
    “...ObjectiveTo investigate medications associated with cognitive function.DesignPopulation-based cross-sectional cohort study.SettingUK Biobank.ParticipantsUK...”
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  • 11
    Cover Image Journal Article
    Determining the Molecular Pathways Underlying the Protective Effect of Non-Steroidal Anti-Inflammatory Drugs for Alzheimer's Disease: A Bioinformatics Approach
    by Nevado-Holgado, Alejo J   Lovestone, Simon Published in Computational and structural biotechnology journal (2017)
    “...Alzheimer's disease (AD) represents a substantial unmet need, due to increasing prevalence in an ageing society and the absence of a disease modifying therapy...”
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  • 12
    Cover Image Journal Article
    NOMINATION OF JAK-STAT SIGNALLING AS A TARGET FOR AD THERAPY THROUGH CLINICAL AND MOLECULAR INFORMATICS
    by Nevado-Holgado, Alejo J   Ribe, Elena M   Kim, Chi-Hun   Furlong, Laura   Mayer, Miguel-Angel   Lovestone, Simon Published in Alzheimer's & dementia (01.07.2017)
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  • 13
    Cover Image Journal Article
    LEVELS OF BLOOD PRESSURE, BODY MASS INDEX AND TOTAL SERUM CHOLESTEROL AT DIFFERENT TIME POINTS PRIOR TO DEMENTIA DIAGNOSIS: A CASE CONTROL STUDY OF OVER 28 MILLION ELECTRONIC HEALT...
    by Perera, Gayan   Gungabissoon, Usha   Alexander, Myriam   Ansel, David   Avillach, Paul   Salles, Talita Duarte   Gordon, Mark Forrest   Nevado-Holgado, Alejo J   Novak, Gerald P   Pasqua, Alessandro   Pedersen, Lars   Ponjoan, Anna   Rijnbeek, Peter   Van Der Lei, Johan   Stewart, Robert Published in Alzheimer's & dementia (01.07.2017)
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  • 14
    Cover Image Journal Article
    A MASS SPECTROMETRY-BASED DISCOVERY AND REPLICATION OF A MULTI-ANALYTE CLASSIFIER FOR NEOCORTICAL AMYLOID PATHOLOGY
    by Ashton, Nicholas J   Nevado-Holgado, Alejo J   Lynham, Steven   Ward, Malcolm   Gupta, Veer Bala   Chatterjee, Pratishtha   Gooze, Kathryn   Hone, Eugene   Pedrini, Steve   Bush, Ashley I   Rowe, Christopher C   Villemagne, Victor L.L   Ames, David   Masters, Colin L   Aarsland, Dag   Lovestone, Simon   Martins, Ralph N   Hye, Abdul Published in Alzheimer's & dementia (01.07.2017)
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  • 15
    Cover Image Journal Article
    Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study
    by Newby, Danielle   Prieto-Alhambra, Daniel   Duarte-Salles, Talita   Ansell, David   Pedersen, Lars   van der Lei, Johan   Mosseveld, Mees   Rijnbeek, Peter   James, Glen   Alexander, Myriam   Egger, Peter   Podhorna, Jana   Stewart, Robert   Perera, Gayan   Avillach, Paul   Grosdidier, Solène   Lovestone, Simon   Nevado-Holgado, Alejo J Published in Alzheimer's research & therapy (06.04.2020)
    “...Inflammatory processes have been shown to play a role in dementia. To understand this role, we selected two anti-inflammatory drugs (methotrexate and...”
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  • 16
    Cover Image Journal Article
    Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result
    by Westwood, Sarah   Baird, Alison L   Hye, Abdul   Ashton, Nicholas J   Nevado-Holgado, Alejo J   Anand, Sneha N   Liu, Benjamine   Newby, Danielle   Bazenet, Chantal   Kiddle, Steven J   Ward, Malcolm   Newton, Ben   Desai, Keyur   Tan Hehir, Cristina   Zanette, Michelle   Galimberti, Daniela   Parnetti, Lucilla   Lleó, Alberto   Baker, Susan   Narayan, Vaibhav A   van der Flier, Wiesje M   Scheltens, Philip   Teunissen, Charlotte E   Visser, Pieter Jelle   Lovestone, Simon Published in Frontiers in aging neuroscience (2018)
    “...Background: Blood biomarkers may aid in recruitment to clinical trials of Alzheimer's disease (AD) modifying therapeutics by triaging potential trials...”
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  • 17
    Cover Image Journal Article
    Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer's Disease Therapeutic Development
    by Nevado-Holgado, Alejo J   Ribe, Elena   Thei, Laura   Furlong, Laura   Mayer, Miguel-Angel   Quan, Jie   Richardson, Jill C   Cavanagh, Jonathan   Consortium, Nima   Lovestone, Simon Published in Cells (Basel, Switzerland) (08.05.2019)
    “...As genome-wide association studies (GWAS) have grown in size, the number of genetic variants that have been associated per disease has correspondingly...”
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  • 18
    Cover Image Journal Article
    Mental disorders and intimate partner violence perpetrated by men towards women: A Swedish population-based longitudinal study
    by Yu, Rongqin   Nevado-Holgado, Alejo J   Molero, Yasmina   D'Onofrio, Brian M   Larsson, Henrik   Howard, Louise M   Fazel, Seena   Moyer, Caitlin
    edited by Hay, Phillipa J
    Published in PLoS medicine (17.12.2019)
    “...Using Swedish nationwide registries, we identified men from 9 diagnostic groups over 1998-2013, with sample sizes ranging from 9,529 with autism to 88,182 with...”
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  • 19
    Cover Image Journal Article
    Oscillatory Activity in the Medial Prefrontal Cortex and Nucleus Accumbens Correlates with Impulsivity and Reward Outcome
    by Donnelly, Nicholas A   Holtzman, Tahl   Rich, P Dylan   Nevado-Holgado, Alejo J   Fernando, Anushka B P   Van Dijck, Gert   Holzhammer, Tobias   Paul, Oliver   Ruther, Patrick   Paulsen, Ole   Robbins, Trevor W   Dalley, Jeffrey W
    edited by Tort, Adriano B. L
    Published in PloS one (2014-00-00)
    “...Actions expressed prematurely without regard for their consequences are considered impulsive. Such behaviour is governed by a network of brain regions...”
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  • 20
    Cover Image Journal Article
    Comparing multiple clustering approaches to understand proteomic datasets for improved biomarker detection
    by Winchester, Laura   Shi, Liu   Kormilitzin, Andrey   Nevado‐Holgado, Alejo J Published in Alzheimer's & dementia (01.12.2020)
    “...Background Development of reproducible blood‐based protein biomarker for Alzheimer’s Disease would allow clinicians and researchers to diagnose and potentially...”
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