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1
Journal Article
by Verdelho, Ana Madureira, Sofia Ferro, José M Basile, Anna-Maria Chabriat, Hugues Erkinjuntti, Timo Fazekas, Franz Hennerici, Michael O’Brien, John Pantoni, Leonardo Salvadori, Emilia Scheltens, Philip Visser, Marieke C Wahlund, Lars-Olof Waldemar, Gunhild Wallin, Anders Inzitari, Domenico Published in Journal of neurology, neurosurgery and psychiatry (01.12.2007)“...Background and purpose:Age related white matter changes (ARWMC) are frequent in non-demented old subjects and are associated with impaired cognitive function...”
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by Jokinen, Hanna Ryberg, Charlotte Kalska, Hely Ylikoski, Raija Rostrup, Egill Stegmann, Mikkel B Waldemar, Gunhild Madureira, Sofia Ferro, José M van Straaten, Elizabeth C W Scheltens, Philip Barkhof, Frederik Fazekas, Franz Schmidt, Reinhold Carlucci, Giovanna Pantoni, Leonardo Inzitari, Domenico Erkinjuntti, Timo Published in Journal of neurology, neurosurgery and psychiatry (01.05.2007)“...Background: Previous research has indicated that corpus callosum atrophy is associated with global cognitive decline in neurodegenerative diseases, but few...”
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3
Journal Article
“...White matter hyperintensities (WMHs) in the brain are the consequence of cerebral small vessel disease, and can easily be detected on MRI. Over the past three...”
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4
Journal Article
by Van Der Flier, Wiesje M Scheltens, Philip“...The Alzheimer center of the VU University Medical Center opened in 2000 and was initiated to combine both patient care and research. Together, to date, all...”
edited by Tabaton, Massimo Zhu, Xiongwei Perry, George Avila, Jesus
Published in Journal of Alzheimer's disease (01.01.2018)
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5
Journal Article
by Dubois, Bruno, MD Feldman, Howard H, MD Jacova, Claudia, PhD DeKosky, Steven T, MD Barberger-Gateau, Pascale, MD Cummings, Jeffrey, MD Delacourte, André, PhD Galasko, Douglas, MD Gauthier, Serge, MD Jicha, Gregory, MD Meguro, Kenichi, MD O'Brien, John, MD Pasquier, Florence, MD Robert, Philippe, MD Rossor, Martin, MD Salloway, Steven, MD Stern, Yaakov, PhD Visser, Pieter J, MD Scheltens, Philip, MD Published in Lancet neurology (2007)“...Summary The NINCDS–ADRDA and the DSM-IV-TR criteria for Alzheimer's disease (AD) are the prevailing diagnostic standards in research; however, they have now...”
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Journal Article
“...Background: Alzheimer's disease is a heterogenous disorder with multiple phenotypes and genotypes, although they eventually converge to a final common...”
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7
Journal Article
by Frisoni, G.B Fox, N.C Jack, C.R Scheltens, P Thompson, P.M Published in Nature reviews. Neurology (2010)“...Structural imaging based on magnetic resonance is an integral part of the clinical assessment of patients with suspected Alzheimer dementia. Prospective data...”
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8
Journal Article
“...North America, Europe/UK, Australia, China, Taiwan, and South Korea predominate, but Africa, India, South America, and Middle Eastern submissions and...”
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Journal Article
by Biessels, Geert Jan Staekenborg, Salka Brunner, Eric Brayne, Carol Scheltens, Philip Published in Lancet neurology (2006)“...The relation between diabetes and major types of dementia is controversial. This systematic review examines the incidence of dementia in people with diabetes...”
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10
Journal Article
by van der Flier, Wiesje M, PhD Pijnenburg, Yolande AL, MD Fox, Nick C, Prof Scheltens, Philip, Prof Published in Lancet neurology (2010)“...Summary Some patients with early-onset Alzheimer's disease (AD) present with a distinct phenotype. Typically, the first and most salient characteristic of AD...”
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11
Journal Article
by Cummings, Jeffrey Aisen, Paul S DuBois, Bruno Froelich, Lutz Jack, Clifford R., Jr Jones, Roy W Morris, John C Raskin, Joel Dowsett, Sherie A Scheltens, Philip Published in Alzheimer's research & therapy (20.09.2016)“...The global impact of Alzheimer’s disease (AD) continues to increase, and focused efforts are needed to address this immense public health challenge. National...”
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12
Journal Article
by Molinuevo, José Luis Ayton, Scott Batrla, Richard Bednar, Martin M Bittner, Tobias Cummings, Jeffrey Fagan, Anne M Hampel, Harald Mielke, Michelle M Mikulskis, Alvydas O’Bryant, Sid Scheltens, Philip Sevigny, Jeffrey Shaw, Leslie M Soares, Holly D Tong, Gary Trojanowski, John Q Zetterberg, Henrik Blennow, Kaj Published in Acta neuropathologica (01.12.2018)“...Alzheimer’s disease (AD) is a progressive neurodegenerative disease with a complex and heterogeneous pathophysiology. The number of people living with AD is...”
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13
Journal Article
by Cummings, Jeffrey Feldman, Howard H Scheltens, Philip Published in Alzheimer's research & therapy (31.08.2019)“...There is a high rate of failure in Alzheimer's disease (AD) drug development with 99% of trials showing no drug-placebo difference. This low rate of success...”
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14
Journal Article
by Dubois, Bruno, Prof Feldman, Howard H, Prof Jacova, Claudia, PhD Cummings, Jeffrey L, MD DeKosky, Steven T, Prof Barberger-Gateau, Pascale, MD Delacourte, André, PhD Frisoni, Giovanni, Prof Fox, Nick C, Prof Galasko, Douglas, Prof Gauthier, Serge, Prof Hampel, Harald, Prof Jicha, Gregory A, MD Meguro, Kenichi, MD O'Brien, John, DM Pasquier, Florence, Prof Robert, Philippe, Prof Rossor, Martin, Prof Salloway, Steven, Prof Sarazin, Marie, MD de Souza, Leonardo C, MD Stern, Yaakov, Prof Visser, Pieter J, MD Scheltens, Philip, Prof Published in Lancet neurology (2010)“...Summary Alzheimer's disease (AD) is classically defined as a dual clinicopathological entity. The recent advances in use of reliable biomarkers of AD that...”
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Journal Article
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Journal Article
by Biessels, Geert Jan Nobili, Flavio Teunissen, Charlotte E Simó, Rafael Scheltens, Philip Published in Lancet neurology (01.08.2020)“...People with type 2 diabetes are at an increased risk of cognitive impairment and dementia (including Alzheimer's disease), as well as subtle forms of cognitive...”
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17
Journal Article
“...Alzheimer's disease (AD) is the most common neurodegenerative disorder and the most prevalent cause of dementia with ageing. Pharmacological treatment of AD is...”
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18
Journal Article
by Ossenkoppele, Rik Jansen, Willemijn J Rabinovici, Gil D Knol, Dirk L van der Flier, Wiesje M van Berckel, Bart N. M Scheltens, Philip Visser, Pieter Jelle Verfaillie, Sander C. J Zwan, Marissa D Adriaanse, Sofie M Lammertsma, Adriaan A Barkhof, Frederik Jagust, William J Miller, Bruce L Rosen, Howard J Landau, Susan M Villemagne, Victor L Rowe, Christopher C Lee, Dong Y Na, Duk L Seo, Sang W Sarazin, Marie Roe, Catherine M Sabri, Osama Barthel, Henryk Koglin, Norman Hodges, John Leyton, Cristian E Vandenberghe, Rik van Laere, Koen Drzezga, Alexander Forster, Stefan Grimmer, Timo Sánchez-Juan, Pascual Carril, Jose M Mok, Vincent Camus, Vincent Klunk, William E Cohen, Ann D Meyer, Philipp T Hellwig, Sabine Newberg, Andrew Frederiksen, Kristian S Fleisher, Adam S Mintun, Mark A Wolk, David A Nordberg, Agneta Rinne, Juha O Chételat, Gaël Lleo, Alberto Blesa, Rafael Fortea, Juan Madsen, Karine Rodrigue, Karen M Brooks, David J Published in JAMA : the journal of the American Medical Association (19.05.2015)“...IMPORTANCE: Amyloid-β positron emission tomography (PET) imaging allows in vivo detection of fibrillar plaques, a core neuropathological feature of Alzheimer...”
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19
Journal Article
by Verberk, Inge M.W Slot, Rosalinde E Verfaillie, Sander C.J Heijst, Hans Prins, Niels D van Berckel, Bart N.M Scheltens, Philip Teunissen, Charlotte E van der Flier, Wiesje M Published in Annals of neurology (01.11.2018)“...Objective: We investigated the association of plasma amyloid beta (Abeta)40, Abeta42, and total tau (tTau) with the presence of Alzheimer pathological changes...”
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20
Journal Article
by Gouw, Alida A Seewann, Alexandra van der Flier, Wiesje M Barkhof, Frederik Rozemuller, Annemieke M Scheltens, Philip Geurts, Jeroen J G Published in Journal of neurology, neurosurgery and psychiatry (01.02.2011)“...BackgroundWhite matter hyperintensities (WMH), lacunes and microbleeds are regarded as typical MRI expressions of cerebral small vessel disease (SVD) and they...”
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