Search Results - "Shyian, Maksym"

Journal Article

Rif1 Controls DNA Replication Timing in Yeast through the PP1 Phosphatase Glc7

by Mattarocci, Stefano Shyian, Maksym Lemmens, Laure Damay, Pascal Altintas, Dogus Murat Shi, Tianlai Bartholomew, Clinton R Thomä, Nicolas H Hardy, Christopher F J Shore, David Published in Cell reports (Cambridge) (10.04.2014)

“...The Rif1 protein, originally identified as a telomere-binding factor in yeast, has recently been implicated in DNA replication control from yeast to metazoans...”

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Journal Article

Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends

by Mattarocci, Stefano Reinert, Julia K Bunker, Richard D Fontana, Gabriele A Shi, Tianlai Klein, Dominique Cavadini, Simone Faty, Mahamadou Shyian, Maksym Hafner, Lukas Shore, David Thomä, Nicolas H Rass, Ulrich Published in Nature structural & molecular biology (01.07.2017)

“...In yeast, Rif1 is part of the telosome, where it inhibits telomerase and checkpoint signaling at chromosome ends. In mammalian cells, Rif1 is not telomeric,...”

Journal Article

Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration

by Hafner, Lukas Lezaja, Aleksandra Zhang, Xu Lemmens, Laure Shyian, Maksym Albert, Benjamin Follonier, Cindy Nunes, Jose Manuel Lopes, Massimo Shore, David Mattarocci, Stefano Published in Cell reports (Cambridge) (24.04.2018)

“...The Saccharomyces cerevisiae telomere-binding protein Rif1 plays an evolutionarily conserved role in control of DNA replication timing by promoting...”

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Journal Article

Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication

by Shyian, Maksym Mattarocci, Stefano Albert, Benjamin Hafner, Lukas Lezaja, Aleksandra Costanzo, Michael Boone, Charlie Shore, David
edited by Branzei, Dana
Published in PLoS genetics (01.11.2016)

“...The Rif1 protein is a negative regulator of DNA replication initiation in eukaryotes. Here we show that budding yeast Rif1 inhibits DNA replication initiation...”

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Journal Article

Fork pausing complex engages topoisomerases at the replisome

by Shyian, Maksym Albert, Benjamin Zupan, Andreja Moset Ivanitsa, Vitalii Charbonnet, Gabriel Dilg, Daniel Shore, David Published in Genes & development (01.01.2020)

“...In this study, Shyian et al. set out to address mechanistically how the evolutionarily conserved fork pausing complex acts at proteinaceous replication fork...”

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Journal Article

Fork pausing complex engages topoisomerases at the replisome

by Shyian, Maksym Albert, Benjamin Zupan, Andreja Moset Ivanitsa, Vitalii Charbonnet, Gabriel Dilg, Daniel Shore, David Published in Genes & development (01.01.2020)

“...Replication forks temporarily or terminally pause at hundreds of hard-to-replicate regions around the genome. A conserved pair of budding yeast replisome...”

Journal Article

Rif1: A Conserved Regulator of DNA Replication and Repair Hijacked by Telomeres in Yeasts

by Mattarocci, Stefano Hafner, Lukas Lezaja, Aleksandra Shyian, Maksym Shore, David Published in Frontiers in genetics (2016-00-00)

“...Rap1-interacting factor 1 (Rif1) was originally identified in the budding yeast Saccharomyces cerevisiae as a telomere-binding protein that negatively...”

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Journal Article

Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration

by Hafner, Lukas Lezaja, Aleksandra Zhang, Xu Lemmens, Laure Shyian, Maksym Albert, Benjamin Follonier, Cindy Nunes, Jose Manuel Lopes, Massimo Shore, David Mattarocci, Stefano
24.04.2018

“...The Saccharomyces cerevisiae telomere-binding protein Rif1 plays an evolutionarily conserved role in control of DNA replication timing by promoting...”

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Journal Article

Preliminary study of thyroid and colon cancers-associated antigens and their cognate autoantibodies as potential cancer biomarkers

by Kiyamova, Ramziya Garifulin, Oleg Gryshkova, Vitalina Kostianets, Olga Shyian, Maksym Gout, Ivan Filonenko, Valeriy Published in Biomarkers (01.06.2012)

“...Background: Autoantibodies, which are produced against tumor-associated antigens, are potential tumor markers and attract a growing interest for cancer...”

Journal Article

Serological Analysis of SEREX-Defined Medullary Breast Carcinoma-Associated Antigens

by Kostianets, Olga Shyian, Maksym Sergiy, Demidov Antoniuk, Stepan Gout, Ivan Filonenko, Valeriy Kiyamova, Ramziya Published in Cancer investigation (24.07.2012)

“...Medullary breast carcinoma (MBC) despite anaplastic features and high grade has a good prognosis that can be related to prominent lymphocytic infiltration. We...”

Publication

On start and pause of replication fork

by Shyian, Maksym
01.01.2018

“...In my PhD thesis I describe the work I’ve done with my colleagues in Professor David Shore’s Lab that led to the next 3 main conclusions. (1) Conserved protein...”

Journal Article

Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication

by Shyian, Maksym Mattarocci, Stefano Albert, Benjamin Hafner, Lukas Lezaja, Aleksandra Costanzo, Michael Boone, Charlie Shore, David Published in PLoS Genetics (01.11.2016)

“...The Rif1 protein is a negative regulator of DNA replication initiation in eukaryotes. Here we show that budding yeast Rif1 inhibits DNA replication initiation...”

Journal Article

Rif1: A Conserved Regulator of DNA Replication and Repair Hijacked by Telomeres in Yeasts

by Mattarocci, Stefano Hafner, Lukas Lezaja, Aleksandra Shyian, Maksym Shore, David Published in Frontiers in Genetics (30.03.2016)

“...Rap1-interacting factor 1 (Rif1) was originally identified in the budding yeast Saccharomyces cerevisiae as a telomere-binding protein that negatively...”

Journal Article

Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration

“...The Saccharomyces cerevisiae telomere-binding protein Rif1 plays an evolutionarily conserved role in control of DNA replication timing by promoting...”

Publication

Referee report. For: Investigating the role of Rts1 in DNA replication initiation [version 1; referees: 2 approved]

by Shore, David Shyian, Maksym
01.01.2018

Data Set

Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication

by Shyian, Maksym Mattarocci, Stefano Albert, Benjamin Hafner, Lukas Lezaja, Aleksandra Costanzo, Michael Boone, Charlie Shore, David
01.01.2016

“...The Rif1 protein is a negative regulator of DNA replication initiation in eukaryotes. Here we show that budding yeast Rif1 inhibits DNA replication initiation...”

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