Search Results - "Thai, Khac-Minh"

Journal Article

Identification of an Immune Gene Expression Signature for Predicting Lung Squamous Cell Carcinoma Prognosis

by Yan, Yubo Zhang, Minghui Xu, Shanqi Xu, Shidong
edited by Thai, Khac-Minh
Published in BioMed research international (28.06.2020)

“...Growing evidence indicates that immune-related biomarkers play an important role in tumor processes. This study investigates immune-related gene expression and...”

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Journal Article

Molecular Epidemiology of GI.3 Norovirus Outbreaks from Acute Gastroenteritis Surveillance System in Taiwan, 2015–2019

by Chiu, Shu-Chun Hsu, Jia-Kai Hu, Szu-Chieh Wu, Ching-Yi Wang, Ying-Chin Lin, Jih-Hui
edited by Thai, Khac-Minh
Published in BioMed research international (13.02.2020)

“...Norovirus is the leading cause of food-borne disease outbreaks. We conducted this study to examine the incidence and molecular characteristics of norovirus...”

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Journal Article

How Have Intravitreal Anti-VEGF and Dexamethasone Implant Been Used in Italy? A Multiregional, Population-Based Study in the Years 2010–2016

by Scondotto, Giulia Sultana, Janet Ientile, Valentina Ingrasciotta, Ylenia Fontana, Andrea Copetti, Massimiliano Mirabelli, Eliana Trombetta, Costantino J Rapisarda, Carlo Reibaldi, Michele Avitabile, Teresio Longo, Antonio Toro, Patricia Ibanez Vadalà, Maria Cillino, Salvatore Virgili, Gianni Gini, Rosa Leoni, Olivia Pollina Addario, Sebastiano Walter Cananzi, Pasquale La Cavera, Claudia Puzo, Maria Rosalia De Sarro, Giovambattista De Francesco, Adele Trifirò, Gianluca
edited by Thai, Khac-Minh
Published in BioMed research international (11.01.2020)

“...Purpose. To describe intravitreal anti-VEGF drug and dexamethasone use in four Italian regions. Methods. Four regional claims databases were used to measure...”

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Journal Article

Effect of Lonicera caerulea var. emphyllocalyx Fruit on Biofilm Formed by Porphyromonas gingivalis

by Minami, Masaaki Takase, Hiroshi Nakamura, Mineo Makino, Toshiaki
edited by Thai, Khac-Minh
Published in BioMed research international (10.12.2019)

“...Porphyromonas gingivalis is an important pathogenic anaerobic bacterium that causes aspiration pneumonia. This bacterium frequently forms biofilms in the oral...”

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Journal Article

Examining Socioeconomic and Computational Aspects of Vaccine Pharmacovigilance

by Soldatou, Vasiliki Soldatos, Anastasios Soldatos, Theodoros
edited by Thai, Khac-Minh
Published in BioMed research international (19.02.2019)

“...Background. Vaccine pharmacovigilance relates to the detection of adverse events, their assessment, understanding, and prevention, and communication of their...”

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Journal Article

Serum Human Epididymis Protein 4 is Associated with Renal Function and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus

by Zhang, Miaomiao Zhao, Bing Xie, Jing Liang, Yan Yang, Zaixing
edited by Thai, Khac-Minh
Published in BioMed research international (11.11.2019)

“...Human epididymis protein 4 (HE4) is an available tumor biomarker mainly for detecting ovarian cancer. However, it is unknown whether it can be a novel...”

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Journal Article

Cinnamide derivatives as mammalian arginase inhibitors: synthesis, biological evaluation and molecular docking

by Pham, Thanh-Nhat Bordage, Simon Pudlo, Marc Demougeot, Céline Thai, Khac-Minh Girard-Thernier, Corine Published in International journal of molecular sciences (29.09.2016)

“...Arginases are enzymes that are involved in many human diseases and have been targeted for new treatments. Here a series of cinnamides was designed, synthesized...”

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Journal Article

Synthesis and antibacterial activity of some heterocyclic chalcone analogues alone and in combination with antibiotics

by Tran, Thanh-Dao Nguyen, Thi-Thao-Nhu Do, Tuong-Ha Huynh, Thi-Ngoc-Phuong Tran, Cat-Dong Thai, Khac-Minh Published in Molecules (Basel, Switzerland) (01.06.2012)

“...A series of simple heterocyclic chalcone analogues have been synthesized by Claisen Schmidt condensation reactions between substituted benzaldehydes and...”

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Journal Article

Synthesis and Selective Cytotoxic Activities on Rhabdomyosarcoma and Noncancerous Cells of Some Heterocyclic Chalcones

by Do, Tuong-Ha Nguyen, Dai-Minh Truong, Van-Dat Do, Thi-Hong-Tuoi Le, Minh-Tri Pham, Thanh-Quan Thai, Khac-Minh Tran, Thanh-Dao Published in Molecules (Basel, Switzerland) (09.03.2016)

“...Chemically diverse heterocyclic chalcones were prepared and evaluated for cytotoxicity, aiming to push forward potency and selectivity. They were tested...”

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Journal Article

QSAR modeling on benzo[c]phenanthridine analogues as topoisomerase I inhibitors and anti-cancer agents

by Thai, Khac-Minh Bui, Quang-Huynh Tran, Thanh-Dao Huynh, Thi-Ngoc-Phuong Published in Molecules (Basel, Switzerland) (11.05.2012)

“...Benzo[c]phenanthridine (BCP) derivatives were identified as topoisomerase I (TOP-I) targeting agents with pronounced antitumor activity. In this study,...”

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Journal Article

Synthesis of Novel Chalcones as Acetylcholinesterase Inhibitors

by Tran, Thanh-Dao Nguyen, Thi-Cam-Vi Nguyen, Ngoc-Son Nguyen, Dai-Minh Nguyen, Thi-Thu-Ha Le, Minh-Tri Thai, Khac-Minh Published in Applied sciences (07.07.2016)

“...A new series of benzylaminochalcone derivatives with different substituents on ring B were synthesized and evaluated as inhibitors of acetylcholinesterase. The...”

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Journal Article

A Support Vector Machine Classification Model for Benzo[c]phenathridine Analogues with Topoisomerase-I Inhibitory Activity

by Thai, Khac-Minh Nguyen, Thuy-Quyen Ngo, Trieu-Du Tran, Thanh-Dao Huynh, Thi-Ngoc-Phuong Published in Molecules (Basel, Switzerland) (17.04.2012)

“...Benzo[c]phenanthridine (BCP) derivatives were identified as topoisomerase I (TOP-I) targeting agents with pronounced antitumor activity. In this study, a...”

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Journal Article

Design of Curcumin and Flavonoid Derivatives with Acetylcholinesterase and Beta-Secretase Inhibitory Activities Using in Silico Approaches

by Tran, Thai-Son Le, Minh-Tri Tran, Thanh-Dao Tran, The-Huan Thai, Khac-Minh Published in Molecules (Basel, Switzerland) (10.08.2020)

“...Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are the two crucial enzymes involved in the pathology of Alzheimer's disease. The former is responsible...”

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Journal Article

Synthesis, In Silico and In Vitro Evaluation for Acetylcholinesterase and BACE-1 Inhibitory Activity of Some N -Substituted-4-Phenothiazine-Chalcones

by Tran, Thai-Son Le, Minh-Tri Nguyen, Thi-Cam-Vi Tran, The-Huan Tran, Thanh-Dao Thai, Khac-Minh Published in Molecules (Basel, Switzerland) (27.08.2020)

“...Acetylcholinesterase (AChE) and beta-secretase (BACE-1) are two attractive targets in the discovery of novel substances that could control multiple aspects of...”

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Journal Article

Identification of Novel Ligands for the Z-DNA Binding Protein by Structure-Based Virtual Screening

by Kim, Yang-Gyun Thai, Khac-Minh Song, Jieun Kim, Kyeong Kyu Park, Hyun-Ju Published in Chemical & pharmaceutical bulletin (2007)

“...We describe the first discovery of small molecules that bind to the Z-DNA binding domain of human ADAR1 (Adenosine Deaminase Acting on RNA 1) by...”

Journal Article

Synthesis, In Silico and In Vitro Evaluation of Some Flavone Derivatives for Acetylcholinesterase and BACE-1 Inhibitory Activity

by Tran, Thai-Son Tran, Thanh-Dao Tran, The-Huan Mai, Thanh-Tan Nguyen, Ngoc-Le Thai, Khac-Minh Le, Minh-Tri Published in Molecules (Basel, Switzerland) (05.09.2020)

“...Acetylcholinesterase (AChE) and β-secretase (BACE-1) have become attractive therapeutic targets for Alzheimer's disease (AD). Flavones are flavonoid...”

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Journal Article

Computational assay of Zanamivir binding affinity with original and mutant influenza neuraminidase 9 using molecular docking

by Thai, Khac-Minh Le, Duy-Phong Tran, Nguyen-Viet-Khoa Nguyen, Thi-Thu-Ha Tran, Thanh-Dao Le, Minh-Tri Published in Journal of theoretical biology (21.11.2015)

“...Based upon molecular docking, this study aimed to find notable in silico neuraminidase 9 (NA9) point mutations of the avian influenza A H7N9 virus that possess...”

Journal Article

Computational predictive models for P-glycoprotein inhibition of in-house chalcone derivatives and drug-bank compounds

by Ngo, Trieu-Du Tran, Thanh-Dao Le, Minh-Tri Thai, Khac-Minh Published in Molecular diversity (01.11.2016)

“...The human P-glycoprotein (P-gp) efflux pump is of great interest for medicinal chemists because of its important role in multidrug resistance (MDR). Because of...”

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Journal Article

Prediction model of human ABCC2/MRP2 efflux pump inhibitors: a QSAR study

by Le, Minh-Tri Phan, Thien-Vy Tran-Nguyen, Viet-Khoa Tran, Thanh-Dao Thai, Khac-Minh Published in Molecular diversity (11.02.2020)

“...The overexpression of ABCC2/MRP2, an ATP-binding cassette transporter, contributes to multidrug resistance in cancer cells. In this study, a quantitative...”

Journal Article

Synthesis and phosphodiesterase 5 inhibitory activity of new sildenafil analogues containing a phosphonate group in the 5 ′ -sulfonamide moiety of phenyl ring

by KIM, Dae-Kee JU YOUNG LEE PARK, Hyun-Ju KHAC MINH THAI Published in Bioorganic & medicinal chemistry letters (2004)

“...Synthesis of new sildenafil analogues containing a phosphonate group in the 5(')-sulfonamide moiety of the phenyl ring, 12a-e, 13a-d, and 14a-d, and evaluation...”

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