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3
Book
edited by Turner, Nicholas ¬[Hrsg.]
related Barbieri, Giovanni Francesco ¬[Ill.]
related Gabinetto Disegni e Stampe Florenz
2008
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4
Journal Article
“...Fibroblast growth factors (FGFs) and their receptors control a wide range of biological functions, regulating cellular proliferation, survival, migration and...”
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5
Journal Article
“...Enantiomerically pure chiral amines are valuable building blocks for the synthesis of pharmaceutical drugs and agrochemicals. Indeed it is estimated that...”
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6
Journal Article
“...Summary Despite the success of targeted therapies in the treatment of cancer, the development of resistance limits the ability to translate this method into a...”
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7
Journal Article
Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathwaysby France, Scott P Hepworth, Lorna J Turner, Nicholas J Flitsch, Sabine L Published in ACS catalysis (06.01.2017)“...The combination of sequential biocatalytic reactions, via non-natural synthetic cascades, is a rapidly developing field and leads to the generation of complex...”
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8
Journal Article
by Chetty, Raj Hendren, Nathaniel Kline, Patrick Saez, Emmanuel Turner, Nicholas Published in The American economic review (01.05.2014)“...We present new evidence on trends in intergenerational mobility in the United States using administrative earnings records. We find that percentile rank-based...”
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9
Journal Article
by Chetty, Raj Stepner, Michael Abraham, Sarah Lin, Shelby Scuderi, Benjamin Turner, Nicholas Bergeron, Augustin Cutler, David Published in JAMA : the journal of the American Medical Association (26.04.2016)“...IMPORTANCE: The relationship between income and life expectancy is well established but remains poorly understood. OBJECTIVES: To measure the level, time...”
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10
Journal Article
by Aleku, Godwin A France, Scott P Man, Henry Mangas-Sanchez, Juan Montgomery, Sarah L Sharma, Mahima Leipold, Friedemann Hussain, Shahed Grogan, Gideon Turner, Nicholas J Published in Nature chemistry (01.10.2017)“...Reductive amination is one of the most important methods for the synthesis of chiral amines. Here we report the discovery of an NADP(H)-dependent reductive...”
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11
Journal Article
by Köhler, Valentin Turner, Nicholas J Published in Chemical communications (Cambridge, England) (09.12.2014)“...The concurrent operation of multiple catalysts can lead to enhanced reaction features including (i) simultaneous linear multi-step transformations in a single...”
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12
Journal Article
by Turner, Nicholas J Published in Nature chemical biology (01.08.2009)“...Enzymes are increasingly being used as biocatalysts in the generation of products that have until now been derived using traditional chemical processes. Such...”
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13
Journal Article
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14
Journal Article
by Cristofanilli, Massimo, Prof Turner, Nicholas C, MD Bondarenko, Igor, Prof Ro, Jungsil, MD Im, Seock-Ah, MD Masuda, Norikazu, MD Colleoni, Marco, MD DeMichele, Angela, MD Loi, Sherene, MD Verma, Sunil, MD Iwata, Hiroji, MD Harbeck, Nadia, Prof Zhang, Ke, PhD Theall, Kathy Puyana, MD Jiang, Yuqiu, PhD Bartlett, Cynthia Huang, MD Koehler, Maria, MD Slamon, Dennis, Prof Published in The lancet oncology (2016)“...Summary Background In the PALOMA-3 study, the combination of the CDK4 and CDK6 inhibitor palbociclib and fulvestrant was associated with significant...”
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15
Journal Article
by Turner, Nicholas C, PhD Neven, Patrick, Prof Loibl, Sibylle, Prof Andre, Fabrice, Prof Published in The Lancet (British edition) (2016)“...Summary Oestrogen-receptor-positive breast cancer is the most common subtype of breast cancer. Endocrine therapies that target the dependence of this subtype...”
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16
Journal Article
by Sharma, Mahima Mangas‐Sanchez, Juan Turner, Nicholas J Grogan, Gideon Published in Advanced synthesis & catalysis (19.06.2017)“...Asymmetric reductive aminations are some of the most important reactions in the preparation of active pharmaceuticals, as chiral amines feature in many of the...”
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17
Journal Article
by Turner, Nicholas A Sharma-Kuinkel, Batu K Maskarinec, Stacey A Eichenberger, Emily M Shah, Pratik P Carugati, Manuela Holland, Thomas L Fowler, Jr, Vance G Published in Nature reviews. Microbiology (01.04.2019)“...Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern pathogens. The same organism that lives as a commensal and is...”
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18
Journal Article
by Mutti, F.G Knaus, T Scrutton, N.S Breuer, M Turner, N.J Published in Science (American Association for the Advancement of Science) (25.09.2015)“...α-Chiral amines are key intermediates for the synthesis of a plethora of chemical compounds at industrial scale. We present a biocatalytic hydrogen-borrowing...”
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19
Journal Article
by Turner, Nicholas C Ro, Jungsil André, Fabrice Loi, Sherene Verma, Sunil Iwata, Hiroji Harbeck, Nadia Loibl, Sibylle Huang Bartlett, Cynthia Zhang, Ke Giorgetti, Carla Randolph, Sophia Koehler, Maria Cristofanilli, Massimo Published in The New England journal of medicine (16.07.2015)“...In women with hormone-receptor–positive metastatic breast cancer that had progressed after endocrine therapy, palbociclib plus fulvestrant was associated with...”
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20
Journal Article
by O'Leary, Ben Hrebien, Sarah Morden, James P Beaney, Matthew Fribbens, Charlotte Huang, Xin Liu, Yuan Bartlett, Cynthia Huang Koehler, Maria Cristofanilli, Massimo Garcia-Murillas, Isaac Bliss, Judith M Turner, Nicholas C Published in Nature communications (01.03.2018)“...CDK4/6 inhibition substantially improves progression-free survival (PFS) for women with advanced estrogen receptor-positive breast cancer, although there are...”
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