Search Results - "Turner, Nicholas"

Book

The paintings of Guercino: a revised and expanded catalogue raisonné

by Turner, Nicholas ¬[Zusammenstellender]
2017

Description of contents

Holdings Uni Bonn

Book

Florentine drawings of the sixteenth century

by Turner, Nicholas
1986

Description of contents

Holdings Uni Bonn

Journal Article

Fibroblast growth factor signalling: from development to cancer

by Grose, Richard Turner, Nicholas Published in Nature reviews. Cancer (01.02.2010)

“...Fibroblast growth factors (FGFs) and their receptors control a wide range of biological functions, regulating cellular proliferation, survival, migration and...”

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Journal Article

Biocatalytic Approaches to the Synthesis of Enantiomerically Pure Chiral Amines

by Ghislieri, Diego Ghislieri, Diego Turner, Nicholas J Turner, Nicholas J Published in Topics in catalysis (01.03.2014)

“...Enantiomerically pure chiral amines are valuable building blocks for the synthesis of pharmaceutical drugs and agrochemicals. Indeed it is estimated that...”

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Journal Article

Genetic heterogeneity and cancer drug resistance

by Turner, Nicholas C, PhD Reis-Filho, Jorge S, Prof Published in The lancet oncology (2012)

“...Summary Despite the success of targeted therapies in the treatment of cancer, the development of resistance limits the ability to translate this method into a...”

Book

Guercino - la scuola, la maniera: i disegni agli Uffizi ; [Gabinetto Disegni e Stampe degli Uffizi (17 dicembre 2008 - 2 febbraio 2009), Berna, Kunstmuseum (11 settembre - 22 novem...

edited by Turner, Nicholas ¬[Hrsg.]
related Barbieri, Giovanni Francesco ¬[Ill.]
related Gabinetto Disegni e Stampe Florenz

2008

Description of contents

Holdings Uni Bonn

Journal Article

Constructing Biocatalytic Cascades: In Vitro and in Vivo Approaches to de Novo Multi-Enzyme Pathways

by France, Scott P Hepworth, Lorna J Turner, Nicholas J Flitsch, Sabine L Published in ACS catalysis (06.01.2017)

“...The combination of sequential biocatalytic reactions, via non-natural synthetic cascades, is a rapidly developing field and leads to the generation of complex...”

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Journal Article

The Association Between Income and Life Expectancy in the United States, 2001-2014

by Chetty, Raj Stepner, Michael Abraham, Sarah Lin, Shelby Scuderi, Benjamin Turner, Nicholas Bergeron, Augustin Cutler, David Published in JAMA : the journal of the American Medical Association (26.04.2016)

“...IMPORTANCE: The relationship between income and life expectancy is well established but remains poorly understood. OBJECTIVES: To measure the level, time...”

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Journal Article

Is the United States Still a Land of Opportunity? Recent Trends in Intergenerational Mobility

by Raj Chetty Nathaniel Hendren Patrick Kline Emmanuel Saez Nicholas Turner Published in The American economic review (01.05.2014)

“...We present new evidence on trends in intergenerational mobility in the United States using administrative earnings records. We find that percentile rank-based...”

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Journal Article

Artificial concurrent catalytic processes involving enzymes

by Köhler, Valentin Turner, Nicholas J Published in Chemical communications (Cambridge, England) (09.12.2014)

“...The concurrent operation of multiple catalysts can lead to enhanced reaction features including (i) simultaneous linear multi-step transformations in a single...”

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Journal Article

Endocrine-based therapy versus chemotherapy in advanced breast cancer

by Robert, Marie Turner, Nicholas Published in The lancet oncology (01.12.2019)

Journal Article

Directed evolution drives the next generation of biocatalysts

by Turner, Nicholas J Published in Nature Chemical Biology (01.08.2009)

“...Enzymes are increasingly being used as biocatalysts in the generation of products that have until now been derived using traditional chemical processes. Such...”

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Journal Article

Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrin...

by Cristofanilli, Massimo, Prof Turner, Nicholas C, MD Bondarenko, Igor, Prof Ro, Jungsil, MD Im, Seock-Ah, MD Masuda, Norikazu, MD Colleoni, Marco, MD DeMichele, Angela, MD Loi, Sherene, MD Verma, Sunil, MD Iwata, Hiroji, MD Harbeck, Nadia, Prof Zhang, Ke, PhD Theall, Kathy Puyana, MD Jiang, Yuqiu, PhD Bartlett, Cynthia Huang, MD Koehler, Maria, MD Slamon, Dennis, Prof Published in The lancet oncology (2016)

“...Summary Background In the PALOMA-3 study, the combination of the CDK4 and CDK6 inhibitor palbociclib and fulvestrant was associated with significant...”

Journal Article

A reductive aminase from Aspergillus oryzae

by Aleku, Godwin A France, Scott P Man, Henry Mangas-Sanchez, Juan Montgomery, Sarah L Sharma, Mahima Leipold, Friedemann Hussain, Shahed Grogan, Gideon Turner, Nicholas J Published in Nature chemistry (01.10.2017)

“...Reductive amination is one of the most important methods for the synthesis of chiral amines. Here we report the discovery of an NADP(H)-dependent reductive...”

Journal Article

Advances in the treatment of advanced oestrogen-receptor-positive breast cancer

by Turner, Nicholas C, PhD Neven, Patrick, Prof Loibl, Sibylle, Prof Andre, Fabrice, Prof Published in The Lancet (British edition) (2016)

“...Summary Oestrogen-receptor-positive breast cancer is the most common subtype of breast cancer. Endocrine therapies that target the dependence of this subtype...”

Journal Article

NAD(P)H‐Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application

by Sharma, Mahima Mangas‐Sanchez, Juan Turner, Nicholas J Grogan, Gideon Published in Advanced synthesis & catalysis (19.06.2017)

“...Asymmetric reductive aminations are some of the most important reactions in the preparation of active pharmaceuticals, as chiral amines feature in many of the...”

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Journal Article

Conversion of alcohols to enantiopure amines through dual-enzyme hydrogen-borrowing cascades

by Francesco G. Mutti Tanja Knaus Nigel S. Scrutton Michael Breuer Nicholas J. Turner Published in Science (American Association for the Advancement of Science) (25.09.2015)

“...α-Chiral amines are key intermediates for the synthesis of a plethora of chemical compounds at industrial scale. We present a biocatalytic hydrogen-borrowing...”

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Journal Article

Bacterial Anabaena variabilis phenylalanine ammonia lyase: A biocatalyst with broad substrate specificity

by Lovelock, Sarah L Turner, Nicholas J Published in Bioorganic & medicinal chemistry (15.10.2014)

“...Phenylalanine ammonia lyases (PALs) catalyse the regio- and stereoselective hydroamination of cinnamic acid analogues to yield optically enriched α-amino...”

Journal Article

Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer

by Turner, Nicholas C Ro, Jungsil André, Fabrice Loi, Sherene Verma, Sunil Iwata, Hiroji Harbeck, Nadia Loibl, Sibylle Huang Bartlett, Cynthia Zhang, Ke Giorgetti, Carla Randolph, Sophia Koehler, Maria Cristofanilli, Massimo Published in The New England journal of medicine (16.07.2015)

“...In women with hormone-receptor–positive metastatic breast cancer that had progressed after endocrine therapy, palbociclib plus fulvestrant was associated with...”

Journal Article

Hallmarks of 'BRCAness' in sporadic cancers

by Ashworth, Alan Turner, Nicholas Tutt, Andrew Published in Nature reviews. Cancer (01.10.2004)

“...Germline mutations in the BRCA1, BRCA2 and Fanconi anaemia genes confer cancer susceptibility, and the proteins encoded by these genes have distinct functions...”

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