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1by Bharadwaj, Prashant Wijesekara, Nadeeja Liyanapathirana, Milindu Newsholme, Philip Ittner, Lars Fraser, Paul Verdile, Giuseppe Published in Journal of Alzheimer's disease (2017-00-00)“...A wealth of evidence indicates a strong link between type 2 diabetes (T2D) and neurodegenerative diseases such as Alzheimer's disease (AD). Although the...”
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2by Giuseppe Verdile Kevin N. Keane Vinicius F. Cruzat Sandra Medic Miheer Sabale Joanne Rowles Nadeeja Wijesekara Ralph N. Martins Paul E. Fraser Philip Newsholme“...Type 2 diabetes (T2DM), Alzheimer’s disease (AD), and insulin resistance are age-related conditions and increased prevalence is of public concern. Recent...”
edited by Macciò, Antonio
Published in Mediators of inflammation (01.12.2015)
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3by Wijesekara, Nadeeja Ahrens, Rosemary Sabale, Miheer Wu, Ling Ha, Kathy Verdile, Giuseppe Fraser, Paul E Published in The FASEB journal (01.12.2017)“...ABSTRACT Alzheimer’s disease (AD) and type 2 diabetes (T2D) present a significant risk to each other. AD and T2D are characterized by deposition of cerebral...”
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4by Kaur, Achint Patankar, Jay V de Haan, Willeke Ruddle, Piers Wijesekara, Nadeeja Groen, Albert K Verchere, C. Bruce Singaraja, Roshni R Hayden, Michael R Published in Diabetes (New York, N.Y.) (01.04.2015)“...Besides their role in facilitating lipid absorption, bile acids are increasingly being recognized as signaling molecules that activate cell-signaling...”
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5by Tamara J. Nicolson Elisa A. Bellomo Nadeeja Wijesekara Merewyn K. Loder Jocelyn M. Baldwin Armen V. Gyulkhandanyan Vasilij Koshkin Andrei I. Tarasov Raffaella Carzaniga Katrin Kronenberger Tarvinder K. Taneja Gabriela da Silva Xavier Sarah Libert Philippe Froguel Raphael Scharfmann Volodymir Stetsyuk Philippe Ravassard Helen Parker Fiona M. Gribble Frank Reimann Robert Sladek Stephen J. Hughes Paul R.V. Johnson Myriam Masseboeuf Remy Burcelin Stephen A. Baldwin Ming Liu Roberto Lara-Lemus Peter Arvan Frans C. Schuit Michael B. Wheeler Fabrice Chimienti Guy A. Rutter Published in Diabetes (New York, N.Y.) (01.09.2009)“...Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes–Associated Variants Tamara J...”
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6by Gonçalves, Rafaella Araujo Wijesekara, Nadeeja Fraser, Paul E De Felice, Fernanda G Published in Frontiers in cellular neuroscience (2019-00-00)“...The microtubule-associated protein tau (MAPT) is mainly identified as a tubulin binding protein essential for microtubule dynamics and assembly and for neurite...”
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7by Wijesekara, Nadeeja Kaur, Achint Westwell-Roper, Clara Nackiewicz, Dominika Soukhatcheva, Galina Hayden, Michael R Verchere, C Bruce Published in Diabetologia (01.06.2016)“...Islet amyloid, a pathological feature of type 2 diabetes, forms from the aggregation of islet amyloid polypeptide (IAPP), a beta cell peptide that is produced...”
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8by Nadeeja Wijesekara Amanda Tung Farah Thong Amira Klip Published in American Journal of Physiology - Endocrinology And Metabolism (01.06.2006)“...Contracting skeletal muscle increases glucose uptake to sustain energy demand. This is achieved through a gain in GLUT4 at the membrane, but the traffic...”
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9by Laws, Simon M Gaskin, Scott Woodfield, Amy Srikanth, Velandai Bruce, David Fraser, Paul E Porter, Tenielle Newsholme, Philip Wijesekara, Nadeeja Burnham, Samantha Doré, Vincent Li, Qiao-Xin Maruff, Paul Masters, Colin L Rainey-Smith, Stephanie Rowe, Christopher C Salvado, Olivier Villemagne, Victor L Martins, Ralph N Verdile, Giuseppe Published in Scientific reports (29.08.2017)“...Growing evidence supports the hypothesis that type 2 diabetes (T2D) increases the risk of developing dementia. Experimental evidence from mouse models...”
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10by Gonçalves, Rafaella Araujo Wijesekara, Nadeeja Fraser, Paul E De Felice, Fernanda G Published in Frontiers in endocrinology (Lausanne) (2020-00-00)“...Microtubule-associated protein tau assists in stabilizing microtubules and has been particularly implicated in Alzheimer's disease (AD). Given the importance...”
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11by Nadeeja Wijesekara Daniel Konrad Mohamed Eweida Craig Jefferies Nicole Liadis Adria Giacca Mike Crackower Akira Suzuki Tak W. Mak C. Ronald Kahn Amira Klip Minna Woo Published in Molecular and Cellular Biology (01.02.2005)“...Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley...”
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12by Kruit, Janine K Wijesekara, Nadeeja Westwell-Roper, Clara Vanmierlo, Tim de Haan, Willeke Bhattacharjee, Alpana Tang, Renmei Wellington, Cheryl L LutJohann, Dieter Johnson, James D Brunham, Liam R Verchere, C. Bruce Hayden, Michael R Published in Diabetes (New York, N.Y.) (01.03.2012)“...Cellular cholesterol homeostasis is important for normal [beta]-cell function. Disruption of cholesterol transport by decreased function of the ATP-binding...”
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13by Hongfang Lu Ying Yang Emma M. Allister Nadeeja Wijesekara Michael B. Wheeler Published in Molecular & cellular proteomics (01.08.2008)“...Type 2 diabetes (T2D) arises when pancreatic β-cells fail to compensate for systemic insulin resistance with appropriate insulin secretion. However, the link...”
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14by Wijesekara, Nadeeja Gonçalves, Rafaella Araujo De Felice, Fernanda G Fraser, Paul E Published in Neuropharmacology (01.07.2018)“...Alzheimer's disease (AD) is the most common type of dementia. Recent studies suggest that metabolic disturbances, particularly type 2 diabetes (T2D) increase...”
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15by Wijesekara, Nadeeja Krishnamurthy, Mansa Bhattacharjee, Alpana Suhail, Aamir Sweeney, Gary Wheeler, Michael B Published in The Journal of biological chemistry (29.10.2010)“...The functional impact of adiponectin on pancreatic beta cells is so far poorly understood. Although adiponectin receptors (AdipoR1/2) were identified, their...”
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16by Lu, Hongfang Yang, Ying Allister, Emma M Wijesekara, Nadeeja Wheeler, Michael B Published in Molecular & cellular proteomics (01.08.2008)“...Type 2 diabetes (T2D) arises when pancreatic beta-cells fail to compensate for systemic insulin resistance with appropriate insulin secretion. However, the...”
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17by Wijesekara, Nadeeja Gonçalves, Rafaella Araujo Ahrens, Rosemary De Felice, Fernanda G Fraser, Paul E Published in The FASEB journal (01.06.2018)“...ABSTRACT The microtubule‐associated protein tau is highly expressed in pancreatic islets. Abnormally phosphorylated tau aggregates assemble into...”
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18Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145by Kang, Martin H Zhang, Lin-Hua Wijesekara, Nadeeja de Haan, Willeke Butland, Stefanie Bhattacharjee, Alpana Hayden, Michael R Published in Arteriosclerosis, thrombosis, and vascular biology (01.12.2013)“...OBJECTIVE—The ATP-binding cassette transporter A1 (ABCA1) protein maintains cellular cholesterol homeostasis in several different tissues. In the liver, ABCA1...”
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19by WIJESEKARA, Nadeeja ZHANG, Lin-Hua KANG, Martin H ABRAHAM, Thomas BHATTACHARJEE, Alpana WARNOCK, Garth L VERCHERE, C. Bruce HAYDEN, Michael R Published in Diabetes (New York, N.Y.) (2012)“...Changes in cellular cholesterol affect insulin secretion, and β-cell-specific deletion or loss-of-function mutations in the cholesterol efflux transporter...”
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