Rif1 Binding and Control of Chromosome-Internal DNA Replication Origins Is Limited by Telomere Sequestration

The Saccharomyces cerevisiae telomere-binding protein Rif1 plays an evolutionarily conserved role in control of DNA replication timing by promoting PP1-dependent dephosphorylation of replication initiation factors. However, ScRif1 binding outside of telomeres has never been detected, and it has thus...

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Bibliographic details
Volume:	23
Main Author:	Hafner, Lukas Lezaja, Aleksandra Zhang, Xu Lemmens, Laure Shyian, Maksym Albert, Benjamin Follonier, Cindy Nunes, Jose Manuel Lopes, Massimo Shore, David Mattarocci, Stefano
Format:	Journal Article
Language:	English
Place of publication:	United States Elsevier Inc 24.04.2018 Elsevier
published in:	Cell reports (Cambridge) Vol. 23; no. 4; pp. 983 - 992
Data of publication:	2018-04-24
ISSN:	2211-1247 2211-1247
EISSN:	2211-1247
Discipline:	Biology
Subjects:	DNA replication timing ChEC DNA replication origins Rif1 Rap1 Saccharomyces cerevisiae chromatin endogenous cleavage DNA replication timing ChEC DNA replication origins Rif1 Rap1 Saccharomyces cerevisiae chromatin endogenous cleavage
Online Access:	Fulltext
Database:	Elsevier:ScienceDirect:Open Access ScienceDirect Open Access Titles PubMed CrossRef MEDLINE - Academic Directory of Open Access Journals Database information Databases - DBIS