Cefuroxime plasma and tissue concentrations in patients undergoing elective cardiac surgery: Continuous vs bolus application. A pilot study

Aims Surgical site infections contribute to morbidity and mortality after surgery. The authors hypothesized that higher antibiotic tissue concentrations can be reached for a prolonged time span by continuous administration of prophylactic cefuroxime compared to bolus administration. Methods Twelve p...

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Bibliographic details
Volume: 85
Main Author: Skhirtladze‐Dworschak, Keso
Hutschala, Doris
Reining, Georg
Dittrich, Peter
Bartunek, Anna
Dworschak, Martin
Tschernko, Edda M
Format: Journal Article
Language: English
Zielgruppe: Academic
Place of publication: HOBOKEN WILEY 01.04.2019
Wiley Subscription Services, Inc
John Wiley and Sons Inc
published in: British journal of clinical pharmacology Vol. 85; no. 4; pp. 818 - 826
ORCID: 0000-0002-7790-7829
0000-0002-4074-2266
Data of publication: April 2019
ISSN: 0306-5251
1365-2125
EISSN: 1365-2125
Alternate Title: Skhirtladze‐Dworschak et al
Discipline: Pharmacy, Therapeutics, & Pharmacology
Bibliography: The authors confirm that the PI for this paper is Edda M. Tschernko and that she had direct clinical responsibility for patients.
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Online Access: Fulltext
Database: Wiley Free Content
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