Regulatory role of phosphatidylinositol 3-kinase on TNF-α-induced cyclooxygenase 2 expression in colonic epithelial cells

Background & Aims: Cyclooxygenase (COX)-2 is up-regulated in most colonic cancers and in inflammatory bowel disease in which tumor necrosis factor (TNF)-α is believed to play a central role. There has been recent speculation on the activation of phosphatidylinositol 3-kinase (PI 3-kinase) by TNF...

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Bibliographic details
Volume: 120
Main Author: Weaver, Sean A
Russo, Maria Pia
Wright, Karen L
Kolios, George
Jobin, Christian
Robertson, Duncan A.F
Ward, Stephen G
Format: Journal Article
Language: English
Place of publication: PHILADELPHIA Elsevier Inc 01.04.2001
W B SAUNDERS CO
Elsevier
published in: Gastroenterology (New York, N.Y. 1943) Vol. 120; no. 5; pp. 1117 - 1127
ORCID: 0000-0002-2066-4782
0000-0002-6795-6002
0000-0003-0040-9247
Data of publication: April 2001
ISSN: 0016-5085
1528-0012
EISSN: 1528-0012
Discipline: Medicine
Subjects:
IL
IBD
COX
TNF
MAP
Th2
Online Access: available in Bonn?
CODEN: GASTAB
Database: Web of Knowledge
Science Citation Index Expanded
Web of Science
Web of Science - Science Citation Index Expanded - 2001
Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
Database information Databases - DBIS