A dietary isothiocyanate-enriched moringa (Moringa oleifera) seed extract improves glucose tolerance in a high-fat-diet mouse model and modulates the gut microbiome

[Display omitted] •Isothiocyanate-rich moringa seed extract improves metabolic health in obese mice.•Moringa seed extract modulates antioxidant and inflammatory gene expression.•Moringa seed extract drastically modulates the gut microbiota.•Two potential mechanisms for the anti-diabetic effects of m...

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Bibliographic details
Volume: 47
Main Author: Jaja-Chimedza, Asha
Zhang, Li
Wolff, Khea
Graf, Brittany L
Kuhn, Peter
Moskal, Kristin
Carmouche, Richard
Newman, Susan
Salbaum, J. Michael
Raskin, Ilya
Format: Journal Article
Language: English
Place of publication: AMSTERDAM Elsevier Ltd 01.08.2018
ELSEVIER SCIENCE BV
Elsevier
published in: Journal of functional foods Vol. 47; pp. 376 - 385
ORCID: 0000-0003-4014-0043
0000-0001-5814-5497
Data of publication: August 2018
ISSN: 1756-4646
2214-9414
EISSN: 2214-9414
Discipline: Anatomy & Physiology
Bibliography: Author Contributions: AJC contributed to the development of the project, execution of the experiments, analysis of data and writing the manuscript; IR contributed to the development of the project and writing the manuscript; LZ contributed to the evaluation, analysis and writing of microbiome data; KW and BLG contributed to execution of experiments and data analysis; PK and KM contributed to the development and execution of in vivo studies; RC, SN, MS contributed to execution and processing of microbiome data. Revisions of the manuscript were performed by all authors.
Subjects:
Online Access: Fulltext
Database: Web of Knowledge
Science Citation Index Expanded
Web of Science
Web of Science - Science Citation Index Expanded - 2018
PubMed
CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
Database information Databases - DBIS