Isothiocyanate-enriched moringa seed extract alleviates ulcerative colitis symptoms in mice

Moringa (Moringa oleifera Lam.) seed extract (MSE) has anti-inflammatory and antioxidant activities. We investigated the effects of MSE enriched in moringa isothiocyanate-1 (MIC-1), its putative bioactive, on ulcerative colitis (UC) and its anti-inflammatory/antioxidant mechanism likely mediated thr...

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Volume: 12
Main Author: Kim, Youjin
Wu, Alex G
Jaja-Chimedza, Asha
Graf, Brittany L
Waterman, Carrie
Verzi, Michael P
Raskin, Ilya
Format: Journal Article
Language: English
Zielgruppe: Academic
Place of publication: SAN FRANCISCO PUBLIC LIBRARY SCIENCE 18.09.2017
Public Library of Science
Public Library of Science (PLoS)
published in: PloS one Vol. 12; no. 9; p. e0184709
Editor: Hsieh, Yi-Hsien
ORCID: 0000-0001-8960-3489
Data of publication: 2017-09-18
ISSN: 1932-6203
1932-6203
EISSN: 1932-6203
Alternate Title: Moringa seed extract alleviates ulcerative colitis
Discipline: Sciences (General)
Bibliography: Competing Interests: YK is employed by Nutrasorb, LLC, which has licensed the patent application from its owner - Rutgers University. The funder provided supports in the form of salaries for YK, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section. IR receives consulting income from Nutrasorb, LLC. IR and CW are inventors on a pending US patent application No. 14683730 titled: Extracts from Plants of the Moringaceae Family and Methods of Making. This does not alter our adherence to PLOS ONE policies on sharing data and materials.
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