A systematic review of currently available pharmacological neuroprotective agents as a sole intervention before anticipated or induced cardiac arrest

We conducted a Medline search for controlled studies evaluating currently available drugs for pharmacological neuroprotection. They had to be administered prior to transient global cerebral ischaemia without further non-pharmacological measures. We deliberately excluded focal ischaemia since its pat...

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Bibliographic details

Volume:	65
Main Author:	Weigl, Manuela Tenze, Giacomo Steinlechner, Barbara Skhirtladze, Keso Reining, Georg Bernardo, Mario Pedicelli, Elisa Dworschak, Martin
Format:	Journal Article
Language:	English
Place of publication:	CLARE Elsevier Ireland Ltd 2005 ELSEVIER IRELAND LTD Elsevier
published in:	Resuscitation Vol. 65; no. 1; pp. 21 - 39
Data of publication:	2005
ISSN:	0300-9572 1873-1570
EISSN:	1873-1570
Discipline:	Medicine
Subjects:	Prevention Neurologic dysfunction Brain ischaemia Drug therapy Outcome Cardiac arrest Emergency Medicine Life Sciences & Biomedicine Critical Care Medicine General & Internal Medicine Science & Technology Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Transfusions. Complications. Transfusion reactions. Cell and gene therapy Biological and medical sciences Intensive care medicine Medical sciences Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Central Nervous System Agents - therapeutic use Dopamine - therapeutic use Neuroprotective Agents - therapeutic use Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors Estradiol - therapeutic use Humans Immunosuppressive Agents - therapeutic use Brain Ischemia - prevention & control Brain Ischemia - etiology Enzyme Inhibitors - therapeutic use Magnesium - therapeutic use Progesterone - therapeutic use Cardiovascular Agents - therapeutic use Animals Neurotransmitter Agents - therapeutic use Heart Arrest - prevention & control Potassium Channels - agonists Heart Arrest - complications Disease Models, Animal Prevention Neurologic dysfunction Brain ischaemia Drug therapy Outcome Cardiac arrest IN-VIVO MICRODIALYSIS PROTECTION MECHANISM NIMODIPINE cardiac arrest DAMAGE HIPPOCAMPUS drug therapy neurologic dysfunction NEURONAL DEATH ESTROGEN GLOBAL CEREBRAL-ISCHEMIA outcome prevention BRAIN brain ischaemia Cardiocirculatory arrest Intensive care Outcorne; Prevention Treatment Ischemia Brain ischaemia; Cardiac arrest; Drug therapy; Neurologic dysfunction Central nervous system Cardiovascular disease Neuroprotective agent Resuscitation Encephalon
Online Access:	available in Bonn?
CODEN:	RSUSBS
Database:	Web of Knowledge Science Citation Index Expanded Web of Science - Science Citation Index Expanded - 2005 Web of Science Pascal-Francis MEDLINE (Ovid) PubMed MEDLINE MEDLINE MEDLINE Medline CrossRef Database information Databases - DBIS