Comprehensive genome-wide analysis of routine non-invasive test data allows cancer prediction: A single-center retrospective analysis of over 85,000 pregnancies

Implausible false positive results in non-invasive prenatal testing (NIPT) have been occasionally associated with the detection of occult maternal malignancies. Hence, there is a need for approaches allowing accurate prediction of whether the NIPT result is pointing to an underlying malignancy, as w...

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Bibliographic details
Volume: 35
Main Author: Lenaerts, Liesbeth
Brison, Nathalie
Maggen, Charlotte
Vancoillie, Leen
Che, Huiwen
Vandenberghe, Peter
Dierickx, Daan
Michaux, Lucienne
Dewaele, Barbara
Neven, Patrick
Floris, Giuseppe
Tousseyn, Thomas
Lannoo, Lore
Jatsenko, Tatjana
Bempt, Isabelle Vanden
Van Calsteren, Kristel
Vandecaveye, Vincent
Dehaspe, Luc
Devriendt, Koenraad
Legius, Eric
Bogaert, Kris Van Den
Vermeesch, Joris Robert
Amant, Frédéric
Format: Journal Article
Language: English
Place of publication: Elsevier Ltd 01.05.2021
published in: EClinicalMedicine Vol. 35; p. 100856
ORCID: 0000-0002-5452-4905
Data of publication: May 2021
ISSN: 2589-5370
EISSN: 2589-5370
Discipline: Medicine
Online Access: Fulltext
Database: ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
MEDLINE - Academic
DOAJ Directory of Open Access Journals
Database information Databases - DBIS