Conformationally constrained ethylenediamines: Synthesis and receptor binding of 6,8-diazabicyclo[3.2.2]nonanes

The synthesis and receptor affinity of 6,8-diazabicyclo[3,2,2]nonanes representing conformationally constrained ethylenediamines are described. The Dieckmann analogous cyclization of the (piperazin-2-yl)propionate 9 provided the bicyclononane 10 only, when the first cyclization product was trapped w...

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Bibliographic details
Volume: 10
Main Author: Weigl, M
Bedurftig, S
Maier, CA
Wunsch, B
Format: Journal Article
Language: English
Zielgruppe: Academic
Place of publication: OXFORD PERGAMON-ELSEVIER SCIENCE LTD 01.07.2002
Elsevier Science
Elsevier B.V
published in: Bioorganic & medicinal chemistry Vol. 10; no. 7; pp. 2245 - 2257
Data of publication: 2002-07-01
ISSN: 0968-0896
1464-3391
EISSN: 1464-3391
Discipline: Medicine
Anatomy & Physiology
Chemistry
Subjects:
Rat
Online Access: Fulltext
Database: Web of Science - Science Citation Index Expanded - 2002
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