Development of a selective competitive receptor binding assay for the determination of the affinity to NR2B containing NMDA receptors

A selective, rapid and efficient competitive binding assay for the determination of the affinity of compounds towards the ifenprodil binding site of NR2B subunit containing NMDA receptors has been developed. In the assay system, [ 3H]ifenprodil was used as radioligand and membrane homogenates from L...

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Bibliographic details
Volume: 53
Main Author: Schepmann, Dirk
Frehland, Bastian
Lehmkuhl, Kirstin
Tewes, Bastian
Wünsch, Bernhard
Format: Journal Article
Language: English
Zielgruppe: Academic
Place of publication: AMSTERDAM Elsevier B.V 2010
ELSEVIER SCIENCE BV
Elsevier
published in: Journal of pharmaceutical and biomedical analysis Vol. 53; no. 3; pp. 603 - 608
ORCID: 0000-0002-4725-5428
Data of publication: 2010
ISSN: 0731-7085
1873-264X
EISSN: 1873-264X
Discipline: Pharmacy, Therapeutics, & Pharmacology
Chemistry
Subjects:
Online Access: available in Bonn?
CODEN: JPBADA
Database: Web of Knowledge
Science Citation Index Expanded
Web of Science
Web of Science - Science Citation Index Expanded - 2010
Pascal-Francis
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