Petrosaspongiolides M-R: new potent and selective phospholipase A2 inhibitors from the New Caledonian marine sponge Petrosaspongia nigra

Five new bioactive sesterterpenes (1-5) have been isolated from the New Caledonian marine sponge Petrosaspongia nigra Bergquist and named petrosaspongiolides M-R. Their chemical structures were determined from 1D and 2D NMR studies and MS data. All compounds inhibited different preparations of phosp...

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Bibliographic details
Volume: 61
Main Author: Randazzo, A
Debitus, C
Minale, L
Pastor, P.G
Alcaraz, M.J
Paya, M
Gomez-Paloma, L
Format: Journal Article
Language: English
Place of publication: Washington, DC American Society of Pharmacognosy 01.05.1998
Glendale, AZ American Chemical Society
published in: Journal of natural products (Washington, D.C.) Vol. 61; no. 5; pp. 571 - 575
Data of publication: (May 1998)
ISSN: 0163-3864
1520-6025
EISSN: 1520-6025
Discipline: Chemistry
Biology
Pharmacy, Therapeutics, & Pharmacology
Bibliography: Q60
1997072710
L50
M01
Subjects:
Pig
Online Access: Fulltext
CODEN: JNPRDF
Database: AGRIS
Pascal-Francis
MEDLINE (Ovid)
PubMed
MEDLINE
MEDLINE
MEDLINE
Medline
MEDLINE - Academic
Database information Databases - DBIS