Synthesis and pharmacological evaluation of like- and unlike-configured tetrahydro-2-benzazepines with the α-substituted benzyl moiety in the 5-positionCCDC 987538. For crystallographic data in CIF or other electronic format see DOI: 10.1039/c4ob00510d

A large set of tetrahydro-2-benzazepines with an α-hydroxy or α-(aryl)alkoxy substituted benzyl moiety in the 5-position was prepared according to the recently reported C 6 C 1 + C 3 N synthetic strategy. The Heck reaction of 2-iodobenzaldehyde acetal 4 and the subsequent Stetter reaction led to the...

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Bibliographic details
Volume: 12
Main Author: Hasebein, Peer
Frehland, Bastian
Lehmkuhl, Kirstin
Fröhlich, Roland
Schepmann, Dirk
Wünsch, Bernhard
Format: Journal Article
Language: English
Place of publication: 02.07.2014
Data of publication: 20140702
ISSN: 1477-0520
1477-0539
EISSN: 1477-0539
Discipline: Chemistry
Bibliography: CCDC
10.1039/c4ob00510d
987538
For crystallographic data in CIF or other electronic format see DOI
Online Access: available in Bonn?
Database: Database information not found
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